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Coenzyme A: to make it or uptake it?

Nature reviews. Molecular cell biology, 2016-10, Vol.17 (10), p.605-606

2016

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Impairment of Drosophila orthologs of the human orphan protein C19orf12 induces bang sensitivity and neurodegeneration

PloS one, 2014-02, Vol.9 (2), p.e89439-e89439

2014

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Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility

eLife, 2019-02, Vol.8

2019

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Pantethine rescues a Drosophila model for pantothenate kinase-associated neurodegeneration

Proceedings of the National Academy of Sciences - PNAS, 2010-04, Vol.107 (15), p.6988-6993

2010

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Extracellular 4'-phosphopantetheine is a source for intracellular coenzyme A synthesis

Nature chemical biology, 2015-10, Vol.11 (10), p.784-792

2015

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Activation of Histone Deacetylase-6 Induces Contractile Dysfunction Through Derailment of α-Tubulin Proteostasis in Experimental and Human Atrial Fibrillation

Circulation (New York, N.Y.), 2014-01, Vol.129 (3), p.346-358

2014

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Drosophila Vps13 Is Required for Protein Homeostasis in the Brain

PloS one, 2017-01, Vol.12 (1), p.e0170106-e0170106

2017

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The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity

ACS chemical biology, 2021-11, Vol.16 (11), p.2401-2414

2021

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HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones

Human molecular genetics, 2010-12, Vol.19 (23), p.4677-4693

2010

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Endoplasmic Reticulum Stress Is Associated With Autophagy and Cardiomyocyte Remodeling in Experimental and Human Atrial Fibrillation

Journal of the American Heart Association, 2017-10, Vol.6 (10), p.n/a

2017

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PKAN pathogenesis and treatment

Molecular genetics and metabolism, 2022-11, Vol.137 (3), p.283-291

2022

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De novo CoA biosynthesis is required to maintain DNA integrity during development of the Drosophila nervous system

Human molecular genetics, 2008-07, Vol.17 (13), p.2058-2069

2008

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Thermosensory perception regulates speed of movement in response to temperature changes in Drosophila melanogaster

Journal of experimental biology, 2018-05, Vol.221 (10), p.jeb174151-jeb174151

2018

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Coenzyme A levels influence protein acetylation, CoAlation and 4′-phosphopantetheinylation: Expanding the impact of a metabolic nexus molecule

Biochimica et biophysica acta. Molecular cell research, 2021-04, Vol.1868 (4), p.118965-118965, Article 118965

2021

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Coenzyme A and its derivatives: renaissance of a textbook classic

Biochemical Society transactions, 2014-08, Vol.42 (4), p.1025-1032

2014

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Polarised asymmetric inheritance of accumulated protein damage in higher eukaryotes

PLoS biology, 2006-12, Vol.4 (12), p.e417-e417

2006

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CoA‐dependent activation of mitochondrial acyl carrier protein links four neurodegenerative diseases

EMBO molecular medicine, 2019-12, Vol.11 (12), p.e10488-n/a

2019

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Specific protein homeostatic functions of small heat‐shock proteins increase lifespan

Aging cell, 2016-04, Vol.15 (2), p.217-226

2016

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Guanine quadruplex structures localize to heterochromatin

Nucleic acids research, 2016-01, Vol.44 (1), p.152-163

2016

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4′‐Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN

EMBO molecular medicine, 2019-12, Vol.11 (12), p.e10489-n/a

2019

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A high throughput experimental approach to identify miRNA targets in human cells

Nucleic acids research, 2009-11, Vol.37 (20), p.e137-e137

2009

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Coenzyme A precursors flow from mother to zygote and from microbiome to host

Molecular cell, 2022-07, Vol.82 (14), p.2650-2665.e12

2022

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Coenzyme A, more than 'just' a metabolic cofactor

Biochemical Society transactions, 2014-08, Vol.42 (4), p.1075-1079

2014

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Astrocytic expression of the chaperone DNAJB6 results in non-cell autonomous protection in Huntington’s disease

Neurobiology of disease, 2019-04, Vol.124, p.108-117

2019

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Coenzyme A: to make it or uptake it?

Impairment of Drosophila orthologs of the human orphan protein C19orf12 induces bang sensitivity and neurodegeneration

Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility

Pantethine rescues a Drosophila model for pantothenate kinase-associated neurodegeneration

Extracellular 4'-phosphopantetheine is a source for intracellular coenzyme A synthesis

Activation of Histone Deacetylase-6 Induces Contractile Dysfunction Through Derailment of α-Tubulin Proteostasis in Experimental and Human Atrial Fibrillation

Drosophila Vps13 Is Required for Protein Homeostasis in the Brain

The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity

HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones

Endoplasmic Reticulum Stress Is Associated With Autophagy and Cardiomyocyte Remodeling in Experimental and Human Atrial Fibrillation

PKAN pathogenesis and treatment

De novo CoA biosynthesis is required to maintain DNA integrity during development of the Drosophila nervous system

Thermosensory perception regulates speed of movement in response to temperature changes in Drosophila melanogaster

Coenzyme A levels influence protein acetylation, CoAlation and 4′-phosphopantetheinylation: Expanding the impact of a metabolic nexus molecule

Coenzyme A and its derivatives: renaissance of a textbook classic

Polarised asymmetric inheritance of accumulated protein damage in higher eukaryotes

CoA‐dependent activation of mitochondrial acyl carrier protein links four neurodegenerative diseases

Specific protein homeostatic functions of small heat‐shock proteins increase lifespan

Guanine quadruplex structures localize to heterochromatin

4′‐Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN

A high throughput experimental approach to identify miRNA targets in human cells

Coenzyme A precursors flow from mother to zygote and from microbiome to host

Coenzyme A, more than 'just' a metabolic cofactor

Mutations in PPCS, Encoding Phosphopantothenoylcysteine Synthetase, Cause Autosomal-Recessive Dilated Cardiomyopathy

Astrocytic expression of the chaperone DNAJB6 results in non-cell autonomous protection in Huntington’s disease

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