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RIPK3 in cell death and inflammation: the good, the bad, and the ugly

Immunological reviews, 2017-05, Vol.277 (1), p.102-112

2017

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Comparing the effects of different cell death programs in tumor progression and immunotherapy

Cell death and differentiation, 2019-01, Vol.26 (1), p.115-129

2019

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Oligodendrocyte-derived IL-33 functions as a microglial survival factor during neuroinvasive flavivirus infection

PLoS pathogens, 2023-11, Vol.19 (11), p.e1011350-e1011350

2023

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The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons

Immunity (Cambridge, Mass.), 2019-01, Vol.50 (1), p.64-76.e4

2019

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Catalytic activity of the caspase―8―FLIPL complex inhibits RIPK3-dependent necrosis

Nature (London), 2011-03, Vol.471 (7338), p.363-367

2011

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Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (42), p.17396-17401

2011

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Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3

Nature communications, 2015-06, Vol.6 (1), p.7515-7515, Article 7515

2015

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Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death

Molecular cell, 2015-03, Vol.57 (5), p.860-872

2015

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Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity

Science immunology, 2019-06, Vol.4 (36)

2019

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Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling

Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (20), p.7385-7390

2014

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Survival Function of the FADD-CASPASE-8-cFLIPL Complex

Cell reports (Cambridge), 2012-05, Vol.1 (5), p.401-407

2012

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RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity

Cell reports (Cambridge), 2019-08, Vol.28 (9), p.2275-2287.e5

2019

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Death in the fast lane: what's next for necroptosis?

The FEBS journal, 2016-07, Vol.283 (14), p.2616-2625

Oberst, Andrew

2016

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Widespread Mitochondrial Depletion via Mitophagy Does Not Compromise Necroptosis

Cell reports (Cambridge), 2013-11, Vol.5 (4), p.878-885

2013

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FLIPL induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity

Biochemical journal, 2011-02, Vol.433 (3), p.447-457

2011

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RIPK1 and RIPK3 regulate TNFα-induced β-cell death in concert with caspase activity

Molecular metabolism (Germany), 2022-11, Vol.65, p.101582-101582, Article 101582

2022

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Inducible Dimerization and Inducible Cleavage Reveal a Requirement for Both Processes in Caspase-8 Activation

The Journal of biological chemistry, 2010-05, Vol.285 (22), p.16632-16642

2010

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Autophagy controls the kinetics and extent of mitochondrial apoptosis by regulating PUMA levels

Cell reports (Cambridge), 2014-04, Vol.7 (1), p.45-52

2014

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STING is required for host defense against neuropathological West Nile virus infection

PLoS pathogens, 2019-08, Vol.15 (8), p.e1007899-e1007899

2019

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Mito-priming as a method to engineer Bcl-2 addiction

Nature communications, 2016-02, Vol.7 (1), p.10538-10538, Article 10538

2016

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NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus

The Journal of cell biology, 2017-06, Vol.216 (6), p.1795-1810

2017

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MK2 balances inflammation and cell death

Nature cell biology, 2017-10, Vol.19 (10), p.1150

Oberst, Andrew

2017

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Protective Roles for Caspase-8 and cFLIP in Adult Homeostasis

Cell reports (Cambridge), 2013-10, Vol.5 (2), p.340-348

2013

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Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death

PLoS pathogens, 2016-10, Vol.12 (10), p.e1005910-e1005910

2016

Volltextzugriff (PDF)

Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity

Autophagy, 2014-12, Vol.10 (12), p.2269-2278

2014

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RIPK3 in cell death and inflammation: the good, the bad, and the ugly

Comparing the effects of different cell death programs in tumor progression and immunotherapy

Oligodendrocyte-derived IL-33 functions as a microglial survival factor during neuroinvasive flavivirus infection

The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons

Catalytic activity of the caspase―8―FLIPL complex inhibits RIPK3-dependent necrosis

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3

Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death

Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity

Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling

Survival Function of the FADD-CASPASE-8-cFLIPL Complex

RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity

Death in the fast lane: what's next for necroptosis?

Widespread Mitochondrial Depletion via Mitophagy Does Not Compromise Necroptosis

FLIPL induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity

RIPK1 and RIPK3 regulate TNFα-induced β-cell death in concert with caspase activity

Inducible Dimerization and Inducible Cleavage Reveal a Requirement for Both Processes in Caspase-8 Activation

Autophagy controls the kinetics and extent of mitochondrial apoptosis by regulating PUMA levels

STING is required for host defense against neuropathological West Nile virus infection

Mito-priming as a method to engineer Bcl-2 addiction

NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus

MK2 balances inflammation and cell death

Protective Roles for Caspase-8 and cFLIP in Adult Homeostasis

Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death

Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity

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