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The SGLT2 inhibitor dapagliflozin promotes systemic FFA mobilization, enhances hepatic β-oxidation, and induces ketosis

Journal of lipid research, 2022-03, Vol.63 (3), p.100176-100176, Article 100176

2022

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Uptake and tissue accretion of orally administered free carboxylic acid as compared to ethyl ester form of docosahexaenoic acid (DHA) in the rat

PloS one, 2018-08, Vol.13 (8), p.e0201367-e0201367

2018

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Nicotinic acid timed to feeding reverses tissue lipid accumulation and improves glucose control in obese Zucker rats[S]

Journal of lipid research, 2017-01, Vol.58 (1), p.31-41

2017

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Dosing profile profoundly influences nicotinic acid's ability to improve metabolic control in rats

Journal of lipid research, 2015-09, Vol.56 (9), p.1679-1690

2015

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Pharmacological PPARα activation markedly alters plasma turnover of the amino acids glycine, serine and arginine in the rat

PloS one, 2014-12, Vol.9 (12), p.e113328-e113328

2014

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Thiazolidinediones Increase Plasma-Adipose Tissue FFA Exchange Capacity and Enhance Insulin-Mediated Control of Systemic FFA Availability

Diabetes (New York, N.Y.), 2001-05, Vol.50 (5), p.1158-1165

2001

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Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding

Diabetes (New York, N.Y.), 1997-11, Vol.46 (11), p.1768-1774

1997

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Chronotherapy with a glucokinase activator profoundly improves metabolism in obese Zucker rats

Science translational medicine, 2022-10, Vol.14 (668), p.eabh1316

2022

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193-OR: Chronotherapy with the Glucokinase Activator AZD1656 Greatly Affects Its Ability to Improve Metabolism in Obese Zucker Rats

Diabetes (New York, N.Y.), 2022-06, Vol.71 (Supplement_1)

2022

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The PPARα/γ Agonist, Tesaglitazar, Improves Insulin Mediated Switching of Tissue Glucose and Free Fatty Acid Utilization In Vivo in the Obese Zucker Rat

PPAR Research, 2013-01, Vol.2013 (2013), p.45-58

2013

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Cardiac metabolism in mice: tracer method developments and in vivo application revealing profound metabolic inflexibility in diabetes

American journal of physiology: endocrinology and metabolism, 2006-05, Vol.290 (5), p.E870-E881

2006

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Roles of Fatty Acid Oversupply and Impaired Oxidation in Lipid Accumulation in Tissues of Obese Rats

Journal of Lipids, 2013-01, Vol.2013 (2013), p.77-88

2013

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A new antidiabetic agent, BRL 49653, reduces lipid availability and improves insulin action and glucoregulation in the rat

Diabetes (New York, N.Y.), 1994-10, Vol.43 (10), p.1203-1210

1994

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Involvement of the metabolic sensor GPR81 in cardiovascular control

JCI insight, 2017-10, Vol.2 (19)

2017

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Modeling of free fatty acid dynamics: insulin and nicotinic acid resistance under acute and chronic treatments

Journal of pharmacokinetics and pharmacodynamics, 2017-06, Vol.44 (3), p.203-222

2017

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AZ 242, a novel PPARα/γ agonist with beneficial effects on insulin resistance and carbohydrate and lipid metabolism in ob/ob mice and obese Zucker rats

Journal of lipid research, 2002-11, Vol.43 (11), p.1855-1863

2002

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Development and initial evaluation of a novel method for assessing tissue-specific plasma free fatty acid utilization in vivo using (R)-2-bromopalmitate tracer

Journal of lipid research, 1999-06, Vol.40 (6), p.1155-1169

1999

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Peroxisome Proliferator-Activated Receptor (PPAR) Activation Induces Tissue-Specific Effects on Fatty Acid Uptake and Metabolism in Vivo—A Study Using the Novel PPARα/γ Agonist Tesaglitazar

Endocrinology (Philadelphia), 2004-07, Vol.145 (7), p.3158-3164

2004

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Alterations in the expression and cellular localization of protein kinase C isozymes epsilon and theta are associated with insulin resistance in skeletal muscle of the high-fat-fed rat

Diabetes (New York, N.Y.), 1997-02, Vol.46 (2), p.169-178

1997

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PPARγ agonist induced cardiac enlargement is associated with reduced fatty acid and increased glucose utilization in myocardium of Wistar rats

European journal of pharmacology, 2006-05, Vol.538 (1), p.195-206

2006

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Evaluation of Free Fatty Acid Metabolism in Vivo

Annals of the New York Academy of Sciences, 2002-06, Vol.967 (1), p.158-175

2002

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Uptake and tissue accretion of orally administered free carboxylic acid as compared to ethyl ester form of docosahexaenoic acid

PloS one, 2018-08, Vol.13 (8), p.e0201367

2018

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Reversal of chronic alterations of skeletal muscle protein kinase C from fat-fed rats by BRL-49653

American journal of physiology: endocrinology and metabolism, 1997-11, Vol.273 (5), p.E915-E921

1997

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Pharmacological PPAR[alpha] Activation Markedly Alters Plasma Turnover of the Amino Acids Glycine, Serine and Arginine in the Rat

PloS one, 2014-12, Vol.9 (12)

2014

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Syndromes of insulin resistance in the rat. Inducement by diet and amelioration with benfluorex

Diabetes (New York, N.Y.), 1993-03, Vol.42 (3), p.457-462

1993

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The SGLT2 inhibitor dapagliflozin promotes systemic FFA mobilization, enhances hepatic β-oxidation, and induces ketosis

Uptake and tissue accretion of orally administered free carboxylic acid as compared to ethyl ester form of docosahexaenoic acid (DHA) in the rat

Nicotinic acid timed to feeding reverses tissue lipid accumulation and improves glucose control in obese Zucker rats[S]

Dosing profile profoundly influences nicotinic acid's ability to improve metabolic control in rats

Pharmacological PPARα activation markedly alters plasma turnover of the amino acids glycine, serine and arginine in the rat

Thiazolidinediones Increase Plasma-Adipose Tissue FFA Exchange Capacity and Enhance Insulin-Mediated Control of Systemic FFA Availability

Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding

Chronotherapy with a glucokinase activator profoundly improves metabolism in obese Zucker rats

193-OR: Chronotherapy with the Glucokinase Activator AZD1656 Greatly Affects Its Ability to Improve Metabolism in Obese Zucker Rats

The PPARα/γ Agonist, Tesaglitazar, Improves Insulin Mediated Switching of Tissue Glucose and Free Fatty Acid Utilization In Vivo in the Obese Zucker Rat

Cardiac metabolism in mice: tracer method developments and in vivo application revealing profound metabolic inflexibility in diabetes

Roles of Fatty Acid Oversupply and Impaired Oxidation in Lipid Accumulation in Tissues of Obese Rats

A new antidiabetic agent, BRL 49653, reduces lipid availability and improves insulin action and glucoregulation in the rat

Involvement of the metabolic sensor GPR81 in cardiovascular control

Modeling of free fatty acid dynamics: insulin and nicotinic acid resistance under acute and chronic treatments

AZ 242, a novel PPARα/γ agonist with beneficial effects on insulin resistance and carbohydrate and lipid metabolism in ob/ob mice and obese Zucker rats

Development and initial evaluation of a novel method for assessing tissue-specific plasma free fatty acid utilization in vivo using (R)-2-bromopalmitate tracer

Peroxisome Proliferator-Activated Receptor (PPAR) Activation Induces Tissue-Specific Effects on Fatty Acid Uptake and Metabolism in Vivo—A Study Using the Novel PPARα/γ Agonist Tesaglitazar

Alterations in the expression and cellular localization of protein kinase C isozymes epsilon and theta are associated with insulin resistance in skeletal muscle of the high-fat-fed rat

PPARγ agonist induced cardiac enlargement is associated with reduced fatty acid and increased glucose utilization in myocardium of Wistar rats

Evaluation of Free Fatty Acid Metabolism in Vivo

Uptake and tissue accretion of orally administered free carboxylic acid as compared to ethyl ester form of docosahexaenoic acid

Reversal of chronic alterations of skeletal muscle protein kinase C from fat-fed rats by BRL-49653

Pharmacological PPAR[alpha] Activation Markedly Alters Plasma Turnover of the Amino Acids Glycine, Serine and Arginine in the Rat

Syndromes of insulin resistance in the rat. Inducement by diet and amelioration with benfluorex

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