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Activities of antifolate, antiviral, and other drugs in an immunosuppressed rat model of Pneumocystis carinii pneumonia

Antimicrobial Agents and Chemotherapy, 1992-09, Vol.36 (9), p.1935-1942

1992

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5-Ethoxy-2'-deoxyuridine, a novel substrate for thymidine phosphorylase, potentiates the antitumor activity of 5-fluorouracil when used in combination with interferon, an inducer of thymidine phosphorylase expression

Cancer research (Chicago, Ill.), 1995-08, Vol.55 (16), p.3543-3550

1995

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Potentiation of the antitumor activity of 5-fluorouracil in colon carcinoma cells by the combination of interferon and deoxyribonucleosides results from complementary effects on thymidine phosphorylase

Cancer research (Chicago, Ill.), 1994-03, Vol.54 (6), p.1472-1478

1994

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Guanylhydrazones in therapy of Pneumocystis carinii pneumonia in immunosuppressed rats

Antimicrobial Agents and Chemotherapy, 1994-11, Vol.38 (11), p.2572-2576

1994

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Effects of modifications in the pentose moiety and conformational changes on the binding of nucleoside ligands to uridine phosphorylase from Toxoplasma gondii

Biochemical pharmacology, 1996-06, Vol.51 (12), p.1687-1700

1996

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Effect of the N-glycosidic bond conformation and modifications in the pentose moiety on the binding of nucleoside ligands to uridine phosphorylase

Molecular pharmacology, 1988-08, Vol.34 (2), p.104-110

1988

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4-aza-7,9-dideazaadenosine, a new cytotoxic synthetic C-nucleoside analogue of adenosine

Tetrahedron letters, 1994-07, Vol.35 (30), p.5339-5342

1994

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Synthesis and in vitro cytotoxicity of 6-vinyluridine and related compounds

Bioorganic & medicinal chemistry letters, 1994-02, Vol.4 (3), p.469-472

1994

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Synthesis of pyrrolo[2,1-f][1,2,4]triazine congeners of nucleic acid purines via the N-amination of 2-substituted pyrroles

Journal of heterocyclic chemistry, 1994-07, Vol.31 (4), p.781-786

1994

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A corrected structure for pyrrolosine

Journal of the American Chemical Society, 1992-01, Vol.114 (2), p.668-671

1992

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Synthesis of some new thieno[3,4-d]pyrimidines and their C-nucleosides

Journal of heterocyclic chemistry, 1993-03, Vol.30 (2), p.509-515

1993

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The synthesis of 6,6′-cyclo-6′-deoxyhexofuranosyluracils via a diazomethane-promoted ring-enlargement reaction

Journal of heterocyclic chemistry, 1987-09, Vol.24 (5), p.1439-1444

1987

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Synthesis of furo[3,2- [formula omitted]]pyrimidine nucleosides: A novel c-nucleoside isostere of adenosine

Tetrahedron letters, 1986, Vol.27 (7), p.815-818

1986

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The chemistry of 4-pyrimidinones: Acetylation and ring-opening reactions

Journal of heterocyclic chemistry, 1986-07, Vol.23 (4), p.1239-1243

1986

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Synthesis and NMR studies of some imidazo[4,5-d]pyridazine nucleosides

Journal of heterocyclic chemistry, 1984-03, Vol.21 (2), p.481-489

1984

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Nucleosides. 58. Transformations of pyrimidine nucleosides in alkaline media. 3. The conversion of 5-halogenouridines into imidazoline and barbituric acid nucleosides

Journal of organic chemistry, 1969-05, Vol.34 (5), p.1390-1396

1969

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A novel stereospecific radical cyclization of 2′,3′- O-isopropylideneuridine and -adenosine 5′-aldehyde to the corresponding 6,5′-cyclodihydrouridine and 8,5′-cycloadenosine derivatives

Tetrahedron letters, 1988, Vol.29 (1), p.75-78

1988

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Studies on the Synthesis of Furo[3,2-d]pyrimidine C-Nucleosides: New Inosine Analogues with Antiprotozoan Activity

Nucleosides & nucleotides, 1990-12, Vol.9 (8), p.1021-1043

1990

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Nucleophilic Substitution Reactions of 5-Bromo-6-methyluridines

Nucleosides & nucleotides, 1994-03, Vol.13 (1-3), p.369-378

1994

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A machine learning approach reveals features related to clinicians' diagnosis of clinically relevant knee osteoarthritis

Rheumatology (Oxford, England), 2023-08, Vol.62 (8), p.2732-2739

2023

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Nucleosides and nucleotides. CIIX: Synthesis and optical properties of syn-fixed carbon-briged pyrimidine cyclonucleosides

Chemical & pharmaceutical bulletin, 1992, Vol.40 (7), p.1761-1769

1992

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Synthesis of the Pyrido[4,3-D]pyrimidine Congeners of Inosine and of Adenosine - A New Class of 6:6 Bicyclic C-Ribofuranosides

Nucleosides & nucleotides, 1992-01, Vol.11 (1), p.61-83

1992

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Studies on the chemistry of 5-propynyloxy- and 5-propynylthiopyrimidines: New syntheses of furo- and thieno[3,2-d]pyrimidines

Journal of heterocyclic chemistry, 1989-11, Vol.26 (6), p.1851-1857

1989

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Nucleosides and Nucleotides. 108. Synthesis and Optical Properties of Syn-Fixed Carbon-Bridged Pyrimidine Cyclonucleosides

Chemical and Pharmaceutical Bulletin, 1992/07/25, Vol.40(7), pp.1761-1769

1992

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C-Glycosylation of substituted heterocycles under Friedel-Crafts conditions. I: A two-step synthesis of the thieno[3,4-d]pyrimidine C-nucleoside analog of inosine

Tetrahedron letters, 1988, Vol.29 (29), p.3537-3540

1988

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Activities of antifolate, antiviral, and other drugs in an immunosuppressed rat model of Pneumocystis carinii pneumonia

5-Ethoxy-2'-deoxyuridine, a novel substrate for thymidine phosphorylase, potentiates the antitumor activity of 5-fluorouracil when used in combination with interferon, an inducer of thymidine phosphorylase expression

Potentiation of the antitumor activity of 5-fluorouracil in colon carcinoma cells by the combination of interferon and deoxyribonucleosides results from complementary effects on thymidine phosphorylase

Guanylhydrazones in therapy of Pneumocystis carinii pneumonia in immunosuppressed rats

Effects of modifications in the pentose moiety and conformational changes on the binding of nucleoside ligands to uridine phosphorylase from Toxoplasma gondii

Effect of the N-glycosidic bond conformation and modifications in the pentose moiety on the binding of nucleoside ligands to uridine phosphorylase

4-aza-7,9-dideazaadenosine, a new cytotoxic synthetic C-nucleoside analogue of adenosine

Synthesis and in vitro cytotoxicity of 6-vinyluridine and related compounds

Synthesis of pyrrolo[2,1-f][1,2,4]triazine congeners of nucleic acid purines via the N-amination of 2-substituted pyrroles

A corrected structure for pyrrolosine

Synthesis of some new thieno[3,4-d]pyrimidines and their C-nucleosides

The synthesis of 6,6′-cyclo-6′-deoxyhexofuranosyluracils via a diazomethane-promoted ring-enlargement reaction

Synthesis of furo[3,2- [formula omitted]]pyrimidine nucleosides: A novel c-nucleoside isostere of adenosine

The chemistry of 4-pyrimidinones: Acetylation and ring-opening reactions

Synthesis and NMR studies of some imidazo[4,5-d]pyridazine nucleosides

Nucleosides. 58. Transformations of pyrimidine nucleosides in alkaline media. 3. The conversion of 5-halogenouridines into imidazoline and barbituric acid nucleosides

A novel stereospecific radical cyclization of 2′,3′- O-isopropylideneuridine and -adenosine 5′-aldehyde to the corresponding 6,5′-cyclodihydrouridine and 8,5′-cycloadenosine derivatives

Studies on the Synthesis of Furo[3,2-d]pyrimidine C-Nucleosides: New Inosine Analogues with Antiprotozoan Activity

Nucleophilic Substitution Reactions of 5-Bromo-6-methyluridines

A machine learning approach reveals features related to clinicians' diagnosis of clinically relevant knee osteoarthritis

Nucleosides and nucleotides. CIIX: Synthesis and optical properties of syn-fixed carbon-briged pyrimidine cyclonucleosides

Synthesis of the Pyrido[4,3-D]pyrimidine Congeners of Inosine and of Adenosine - A New Class of 6:6 Bicyclic C-Ribofuranosides

Studies on the chemistry of 5-propynyloxy- and 5-propynylthiopyrimidines: New syntheses of furo- and thieno[3,2-d]pyrimidines

Nucleosides and Nucleotides. 108. Synthesis and Optical Properties of Syn-Fixed Carbon-Bridged Pyrimidine Cyclonucleosides

C-Glycosylation of substituted heterocycles under Friedel-Crafts conditions. I: A two-step synthesis of the thieno[3,4-d]pyrimidine C-nucleoside analog of inosine

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