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Rational targeting of Notch signaling in cancer

Oncogene, 2008-09, Vol.27 (38), p.5124-5131

2008

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Osteopontin mediates an MZF1–TGF-β1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer

Oncogene, 2015-09, Vol.34 (37), p.4821-4833

2015

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Osteopontin mediates an MZF1-TGF- beta 1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer

Oncogene, 2015-09, Vol.34 (37), p.4821-4833

2015

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Targeting both Notch and ErbB-2 signalling pathways is required for prevention of ErbB-2-positive breast tumour recurrence

British journal of cancer, 2011-09, Vol.105 (6), p.796-806

2011

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ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a γ-secretase inhibitor

Oncogene, 2008-08, Vol.27 (37), p.5019-5032

2008

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Paradoxical action of fulvestrant in estradiol-induced regression of tamoxifen-stimulated breast cancer

JNCI : Journal of the National Cancer Institute, 2003-11, Vol.95 (21), p.1597-1608

2003

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Notch-1 activates estrogen receptor-α-dependent transcription via IKKα in breast cancer cells

Oncogene, 2010-01, Vol.29 (2), p.201-213

2010

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Estrogen-induced apoptosis in a breast cancer model resistant to long-term estrogen withdrawal

Journal of steroid biochemistry and molecular biology, 2005-02, Vol.94 (1), p.131-141

2005

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Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells

Oncogenesis (New York, NY), 2013-08, Vol.2 (8), p.e60-e60

2013

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Abstract P3-06-15: Notch3 as a predictor of GSI sensitivity in distinct subtypes of triple negative breast cancer

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.P3-P3-06-15

2016

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Gamma secretase inhibitors of Notch signaling

OncoTargets and therapy, 2013-01, Vol.6, p.943-955

2013

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Notch-1 activates ErbB-2 through a PEA3-dependent mechansim

Cancer research (Chicago, Ill.), 2009-01, Vol.69 (2_Supplement), p.6015

2009

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Cross-talk between Notch and the Estrogen Receptor in Breast Cancer Suggests Novel Therapeutic Approaches

Cancer research (Chicago, Ill.), 2008-07, Vol.68 (13), p.5226-5235

2008

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Intrinsic Mechanism of Estradiol-Induced Apoptosis in Breast Cancer Cells Resistant to Estrogen Deprivation

JNCI : Journal of the National Cancer Institute, 2005-12, Vol.97 (23), p.1746-1759

2005

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Regulation of Estrogen Target Genes and Growth by Selective Estrogen-Receptor Modulators in Endometrial Cancer Cells

Gynecologic oncology, 2002-06, Vol.85 (3), p.498-506

2002

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Abstract P5-04-10: The role of DAXX on enrichment of breast cancer stem cells from ER+ breast cancer

Cancer research (Chicago, Ill.), 2019-02, Vol.79 (4_Supplement), p.P5-P5-04-10

2019

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Abstract P6-05-25: Ratio of notch receptors is critical for response to notch inhibition by a gamma-secretase inhibitor in triple negative breast cancer cells

Cancer research (Chicago, Ill.), 2013-12, Vol.73 (24_Supplement), p.P6-P6-05-25

2013

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Abstract PD7-04: Metabolic syndrome increases risk of recurrence and impacts immune pathways in invasive lobular carcinoma

Cancer research (Chicago, Ill.), 2019-02, Vol.79 (4_Supplement), p.PD7-04-PD7-04

2019

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Abstract P4-08-06: Notch-dependent Regulation of Novel Genes Associated with Trastuzumab Resistance

Cancer research (Chicago, Ill.), 2012-12, Vol.72 (24_Supplement), p.P4-P4-08-06

2012

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Apoptotic action of 17β-estradiol in raloxifene-resistant MCF-7 cells in vitro and in vivo

JNCI : Journal of the National Cancer Institute, 2003-11, Vol.95 (21), p.1586-1597

2003

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Changing role of the oestrogen receptor in the life and death of breast cancer cells

Breast (Edinburgh), 2003-12, Vol.12 (6), p.432-441

2003

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Abstract P2-05-15: Assessment of Notch Signaling Pathway Components as Biomarkers for Triple Negative Breast Cancer: Comparison of Triple Negative Breast Cancer Cell Lines and Human Breast Cancer Samples

Cancer research (Chicago, Ill.), 2012-12, Vol.72 (24_Supplement), p.P2-P2-05-15

2012

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Osteopontin mediates an MZF1-TGF-[beta]1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer

Oncogene, 2015-09, Vol.34 (37), p.4821

2015

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6 INVITED Notch as a potential therapeutic target in cancer

European journal of cancer supplements, 2008, Vol.6 (12), p.4-4

2008

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Notch-1 Confers Resistance to ErbB-2 Targeted Inhibition by Regulating PTEN, p27, and IGF-1R

Cancer research (Chicago, Ill.), 2009-12, Vol.69 (24_Supplement), p.3123-3123

2009

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Rational targeting of Notch signaling in cancer

Osteopontin mediates an MZF1–TGF-β1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer

Osteopontin mediates an MZF1-TGF- beta 1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer

Targeting both Notch and ErbB-2 signalling pathways is required for prevention of ErbB-2-positive breast tumour recurrence

ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a γ-secretase inhibitor

Paradoxical action of fulvestrant in estradiol-induced regression of tamoxifen-stimulated breast cancer

Notch-1 activates estrogen receptor-α-dependent transcription via IKKα in breast cancer cells

Estrogen-induced apoptosis in a breast cancer model resistant to long-term estrogen withdrawal

Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells

Abstract P3-06-15: Notch3 as a predictor of GSI sensitivity in distinct subtypes of triple negative breast cancer

Gamma secretase inhibitors of Notch signaling

Notch-1 activates ErbB-2 through a PEA3-dependent mechansim

Cross-talk between Notch and the Estrogen Receptor in Breast Cancer Suggests Novel Therapeutic Approaches

Intrinsic Mechanism of Estradiol-Induced Apoptosis in Breast Cancer Cells Resistant to Estrogen Deprivation

Regulation of Estrogen Target Genes and Growth by Selective Estrogen-Receptor Modulators in Endometrial Cancer Cells

Abstract P5-04-10: The role of DAXX on enrichment of breast cancer stem cells from ER+ breast cancer

Abstract P6-05-25: Ratio of notch receptors is critical for response to notch inhibition by a gamma-secretase inhibitor in triple negative breast cancer cells

Abstract PD7-04: Metabolic syndrome increases risk of recurrence and impacts immune pathways in invasive lobular carcinoma

Abstract P4-08-06: Notch-dependent Regulation of Novel Genes Associated with Trastuzumab Resistance

Apoptotic action of 17β-estradiol in raloxifene-resistant MCF-7 cells in vitro and in vivo

Changing role of the oestrogen receptor in the life and death of breast cancer cells

Abstract P2-05-15: Assessment of Notch Signaling Pathway Components as Biomarkers for Triple Negative Breast Cancer: Comparison of Triple Negative Breast Cancer Cell Lines and Human Breast Cancer Samples

Osteopontin mediates an MZF1-TGF-[beta]1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer

6 INVITED Notch as a potential therapeutic target in cancer

Notch-1 Confers Resistance to ErbB-2 Targeted Inhibition by Regulating PTEN, p27, and IGF-1R

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