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Host response to nontuberculous mycobacterial infections of current clinical importance

Infection and immunity, 2014-09, Vol.82 (9), p.3516-3522

2014

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Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

Nature immunology, 2008-12, Vol.9 (12), p.1399-1406

2008

Volltextzugriff (PDF)

Mycobacterium tuberculosis nucleoside diphosphate kinase inactivates small GTPases leading to evasion of innate immunity

PLoS pathogens, 2013-07, Vol.9 (7), p.e1003499-e1003499

2013

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A recombinant Mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis

Nature medicine, 2011-10, Vol.17 (10), p.1261-1268

2011

Volltextzugriff (PDF)

Evidence for oxidative stress and defective antioxidant response in guinea pigs with tuberculosis

PloS one, 2011-10, Vol.6 (10), p.e26254

2011

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Differential polarization of alveolar macrophages and bone marrow-derived monocytes following chemically and pathogen-induced chronic lung inflammation

Journal of leukocyte biology, 2010-07, Vol.88 (1), p.159-168

2010

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The Hypervirulent Mycobacterium tuberculosis Strain HN878 Induces a Potent TH1 Response followed by Rapid Down-Regulation

Journal of Immunology, 2007-07, Vol.179 (1), p.522-531

2007

Volltextzugriff (PDF)

Gr1(int)CD11b+ myeloid-derived suppressor cells in Mycobacterium tuberculosis infection

PloS one, 2013, Vol.8 (11), p.e80669-e80669

2013

Volltextzugriff (PDF)

The Efficacy of the BCG Vaccine against Newly Emerging Clinical Strains of Mycobacterium tuberculosis

PloS one, 2015-09, Vol.10 (9), p.e0136500-e0136500

2015

Volltextzugriff (PDF)

Location of Persisting Mycobacteria in a Guinea Pig Model of Tuberculosis Revealed by R207910

Antimicrobial Agents and Chemotherapy, 2007-09, Vol.51 (9), p.3338-3345

2007

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Enhanced priming of adaptive immunity by a proapoptotic mutant of Mycobacterium tuberculosis

The Journal of clinical investigation, 2007-08, Vol.117 (8), p.2279-2288

2007

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Preclinical Testing of the Nitroimidazopyran PA-824 for Activity against Mycobacterium tuberculosis in a Series of In Vitro and In Vivo Models

Antimicrobial Agents and Chemotherapy, 2005-06, Vol.49 (6), p.2294-2301

2005

Volltextzugriff (PDF)

Trying to See the Forest through the Trees: Deciphering the Nature of Memory Immunity to Mycobacterium tuberculosis

Frontiers in immunology, 2018-03, Vol.9, p.461-461

2018

Volltextzugriff (PDF)

Host immune response to rapidly growing mycobacteria, an emerging cause of chronic lung disease

American journal of respiratory cell and molecular biology, 2010-10, Vol.43 (4), p.387-393

2010

Volltextzugriff (PDF)

A new unifying theory of the pathogenesis of tuberculosis

Tuberculosis (Edinburgh, Scotland), 2014-01, Vol.94 (1), p.8-14

Orme, Ian M

2014

Volltextzugriff (PDF)

The balance between protective and pathogenic immune responses in the TB-infected lung

Nature immunology, 2015-01, Vol.16 (1), p.57

2015

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Uptake and accumulation of oxidized low-density lipoprotein during Mycobacterium tuberculosis infection in guinea pigs

PloS one, 2012-03, Vol.7 (3), p.e34148-e34148

2012

Volltextzugriff (PDF)

Comparative Studies Evaluating Mouse Models Used for Efficacy Testing of Experimental Drugs against Mycobacterium tuberculosis

Antimicrobial Agents and Chemotherapy, 2011-03, Vol.55 (3), p.1237-1247

2011

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Virulent clinical isolates of Mycobacterium tuberculosis grow rapidly and induce cellular necrosis but minimal apoptosis in murine macrophages

Journal of leukocyte biology, 2006-01, Vol.79 (1), p.80-86

2006

Volltextzugriff (PDF)

Vaccine Development for Tuberculosis: Current Progress

Drugs (New York, N.Y.), 2013-07, Vol.73 (10), p.1015-1024

Orme, Ian M.

2013

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Defined tuberculosis vaccine, Mtb72F/AS02A, evidence of protection in cynomolgus monkeys

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (7), p.2301-2306

2009

Volltextzugriff (PDF)

Evaluation of Standard Chemotherapy in the Guinea Pig Model of Tuberculosis

Antimicrobial Agents and Chemotherapy, 2010-05, Vol.54 (5), p.1820-1833

2010

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Mycobacterium tuberculosis universal stress protein Rv2623 regulates bacillary growth by ATP-Binding: requirement for establishing chronic persistent infection

PLoS pathogens, 2009-05, Vol.5 (5), p.e1000460

2009

Volltextzugriff (PDF)

Phenotypic Definition of Effector and Memory T-Lymphocyte Subsets in Mice Chronically Infected with Mycobacterium tuberculosis

Clinical and Vaccine Immunology, 2010-04, Vol.17 (4), p.618-625

2010

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The formation of the granuloma in tuberculosis infection

Seminars in immunology, 2014-12, Vol.26 (6), p.601-609

2014

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Host response to nontuberculous mycobacterial infections of current clinical importance

Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

Mycobacterium tuberculosis nucleoside diphosphate kinase inactivates small GTPases leading to evasion of innate immunity

A recombinant Mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis

Evidence for oxidative stress and defective antioxidant response in guinea pigs with tuberculosis

Differential polarization of alveolar macrophages and bone marrow-derived monocytes following chemically and pathogen-induced chronic lung inflammation

The Hypervirulent Mycobacterium tuberculosis Strain HN878 Induces a Potent TH1 Response followed by Rapid Down-Regulation

Gr1(int)CD11b+ myeloid-derived suppressor cells in Mycobacterium tuberculosis infection

The Efficacy of the BCG Vaccine against Newly Emerging Clinical Strains of Mycobacterium tuberculosis

Location of Persisting Mycobacteria in a Guinea Pig Model of Tuberculosis Revealed by R207910

Enhanced priming of adaptive immunity by a proapoptotic mutant of Mycobacterium tuberculosis

Preclinical Testing of the Nitroimidazopyran PA-824 for Activity against Mycobacterium tuberculosis in a Series of In Vitro and In Vivo Models

Trying to See the Forest through the Trees: Deciphering the Nature of Memory Immunity to Mycobacterium tuberculosis

Host immune response to rapidly growing mycobacteria, an emerging cause of chronic lung disease

A new unifying theory of the pathogenesis of tuberculosis

The balance between protective and pathogenic immune responses in the TB-infected lung

Uptake and accumulation of oxidized low-density lipoprotein during Mycobacterium tuberculosis infection in guinea pigs

Comparative Studies Evaluating Mouse Models Used for Efficacy Testing of Experimental Drugs against Mycobacterium tuberculosis

Virulent clinical isolates of Mycobacterium tuberculosis grow rapidly and induce cellular necrosis but minimal apoptosis in murine macrophages

Vaccine Development for Tuberculosis: Current Progress

Defined tuberculosis vaccine, Mtb72F/AS02A, evidence of protection in cynomolgus monkeys

Evaluation of Standard Chemotherapy in the Guinea Pig Model of Tuberculosis

Mycobacterium tuberculosis universal stress protein Rv2623 regulates bacillary growth by ATP-Binding: requirement for establishing chronic persistent infection

Phenotypic Definition of Effector and Memory T-Lymphocyte Subsets in Mice Chronically Infected with Mycobacterium tuberculosis

The formation of the granuloma in tuberculosis infection

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