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Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response

Nature reviews. Cancer, 2015-12, Vol.15 (12), p.712-729

2015

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Obesity and the tumor microenvironment

Science (American Association for the Advancement of Science), 2017-12, Vol.358 (6367), p.1130-1131

2017

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Dysregulated haematopoietic stem cell behaviour in myeloid leukaemogenesis

Nature reviews. Cancer, 2020-07, Vol.20 (7), p.365-382

2020

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Made to order: emergency myelopoiesis and demand-adapted innate immune cell production

Nature reviews. Immunology, 2024-08, Vol.24 (8), p.596-613

2024

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Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy

Cancer research (Chicago, Ill.), 2015-09, Vol.75 (17), p.3479-3491

2015

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CSF-1R inhibition alters macrophage polarization and blocks glioma progression

Nature medicine, 2013-10, Vol.19 (10), p.1264-1272

2013

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Obesity alters the lung myeloid cell landscape to enhance breast cancer metastasis through IL5 and GM-CSF

Nature cell biology, 2017-08, Vol.19 (8), p.974-987

2017

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Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer

Genes & development, 2011-12, Vol.25 (23), p.2465-2479

2011

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Tumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic Agents

Cell reports (Cambridge), 2017-04, Vol.19 (1), p.101-113

2017

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Normal Hematopoiesis Is a Balancing Act of Self-Renewal and Regeneration

Cold Spring Harbor perspectives in medicine, 2020-12, Vol.10 (12), p.a035519

2020

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Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing

Nature cell biology, 2023-01, Vol.25 (1), p.30-41

2023

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Inflammatory Monocytes Promote Perineural Invasion via CCL2-Mediated Recruitment and Cathepsin B Expression

Cancer research (Chicago, Ill.), 2017-11, Vol.77 (22), p.6400-6414

2017

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Microenvironment-mediated resistance to anticancer therapies

Cell research, 2013-02, Vol.23 (2), p.179-181

2013

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Secretory MPP3 reinforce myeloid differentiation trajectory and amplify myeloid cell production

The Journal of experimental medicine, 2023-08, Vol.220 (8)

2023

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TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors

Cell reports (Cambridge), 2016-08, Vol.16 (6), p.1762-1773

2016

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Definition of a Conserved Immunodominant Domain on Hepatitis C Virus E2 Glycoprotein by Neutralizing Human Monoclonal Antibodies

Journal of Virology, 2008-06, Vol.82 (12), p.6061-6066

2008

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A splicing twist on metastasis

Science translational medicine, 2013-01, Vol.5 (169), p.169fs2

2013

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3169 – EPIGENETIC PERTURBATIONS IN HEMATOPOIETIC STEM AND PROGENITOR CELLS LACKING TET2 CAUSE RESISTANCE TO EMERGENCY MYELOPOIESIS

Experimental hematology, 2024-08, Vol.137, p.104489, Article 104489

2024

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A Point Mutation Leading to Hepatitis C Virus Escape from Neutralization by a Monoclonal Antibody to a Conserved Conformational Epitope

Journal of Virology, 2008-06, Vol.82 (12), p.6067-6072

2008

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3143 – GLUTAMINOLYSIS FUELS EMERGENCY MYELOPOIESIS

Experimental hematology, 2024-08, Vol.137, p.104464, Article 104464

2024

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3007 – GLUTAMINOLYSIS FUELS EMERGENCY MYELOPOIESIS

Experimental hematology, 2023, Vol.124, p.S54

2023

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3108 – METABOLIC ADAPTATION IN HEMATOPOIETIC STEM AND PROGENITOR CELLS DURING EMERGENCY MYELOPOIESIS

Experimental hematology, 2021-08, Vol.100, p.S94-S94

2021

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3026 – METABOLIC ADAPTATION IN HEMATOPOIETIC STEM AND PROGENITOR CELLS DURING EMERGENCY MYELOPOIESIS

Experimental hematology, 2020-08, Vol.88, p.S46-S46

2020

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Abstract 549: Sensitization to chemotherapy by inhibition of cathepsin proteases in a mouse model of metastatic breast cancer

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.549-549

2011

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Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response

Obesity and the tumor microenvironment

Dysregulated haematopoietic stem cell behaviour in myeloid leukaemogenesis

Made to order: emergency myelopoiesis and demand-adapted innate immune cell production

Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

Obesity alters the lung myeloid cell landscape to enhance breast cancer metastasis through IL5 and GM-CSF

Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer

Tumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic Agents

Normal Hematopoiesis Is a Balancing Act of Self-Renewal and Regeneration

Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing

Inflammatory Monocytes Promote Perineural Invasion via CCL2-Mediated Recruitment and Cathepsin B Expression

An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis

Microenvironment-mediated resistance to anticancer therapies

Secretory MPP3 reinforce myeloid differentiation trajectory and amplify myeloid cell production

TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors

Definition of a Conserved Immunodominant Domain on Hepatitis C Virus E2 Glycoprotein by Neutralizing Human Monoclonal Antibodies

A splicing twist on metastasis

3169 – EPIGENETIC PERTURBATIONS IN HEMATOPOIETIC STEM AND PROGENITOR CELLS LACKING TET2 CAUSE RESISTANCE TO EMERGENCY MYELOPOIESIS

A Point Mutation Leading to Hepatitis C Virus Escape from Neutralization by a Monoclonal Antibody to a Conserved Conformational Epitope

3143 – GLUTAMINOLYSIS FUELS EMERGENCY MYELOPOIESIS

3007 – GLUTAMINOLYSIS FUELS EMERGENCY MYELOPOIESIS

3108 – METABOLIC ADAPTATION IN HEMATOPOIETIC STEM AND PROGENITOR CELLS DURING EMERGENCY MYELOPOIESIS

3026 – METABOLIC ADAPTATION IN HEMATOPOIETIC STEM AND PROGENITOR CELLS DURING EMERGENCY MYELOPOIESIS

Abstract 549: Sensitization to chemotherapy by inhibition of cathepsin proteases in a mouse model of metastatic breast cancer

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