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Clock gene dysfunction in patients with obstructive sleep apnoea syndrome

The European respiratory journal, 2008-07, Vol.32 (1), p.105-112

2008

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Effects of herbal extracts on the function of human organic anion-transporting polypeptide OATP-B

Drug metabolism and disposition, 2006-04, Vol.34 (4), p.577-582

2006

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Dosing time dependency of doxorubicin-induced cardiotoxicity and bone marrow toxicity in rats

Journal of pharmacy and pharmacology, 2003-06, Vol.55 (6), p.803-810

2003

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Chrono-drug-delivery focused on biological clock: intra- and inter-individual variability of molecular clock

Advanced drug delivery reviews, 2010-07, Vol.62 (9), p.857-858

2010

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Accumulation of sorbitol in the sciatic nerve modulates circadian properties of diabetes-induced neuropathic pain hypersensitivity in a diabetic mouse model

Biochemical and biophysical research communications, 2018-09, Vol.503 (1), p.181-187

2018

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Ternary catalytic α-deuteration of carboxylic acids

Nature Synthesis, 2022-10, Vol.1 (10), p.824-830

2022

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A molecular mechanism regulating circadian expression of vascular endothelial growth factor in tumor cells

Cancer research (Chicago, Ill.), 2003-11, Vol.63 (21), p.7277-7283

2003

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Adrenergic Regulation of Clock Gene Expression in Mouse Liver

Proceedings of the National Academy of Sciences - PNAS, 2003-05, Vol.100 (11), p.6795-6800

2003

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Influence of feeding schedule on the chronopharmacological aspects of sodium valproate in mice

The Journal of pharmacology and experimental therapeutics, 1996-07, Vol.278 (1), p.74

1996

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Changes in toxicity and effectiveness with timing of drug administration: Implications for drug safety

Drug safety, 2003-01, Vol.26 (14), p.999-1010

OHDO, Shigehiro

2003

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Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P‐glycoprotein

Clinical pharmacology and therapeutics, 2002-08, Vol.72 (2), p.209-219

2002

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Population pharmacokinetics of Digoxin in Japanese patients : A 2-compartment pharmacokinetic model

Clinical pharmacokinetics, 2001, Vol.40 (10), p.773-781

2001

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Population pharmacokinetics of haloperidol using Routine clinical pharmacokinetic data in Japanese patients

Clinical pharmacokinetics, 2002, Vol.41 (2), p.153-159

2002

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Effect of Dosing Schedule on Pharmacokinetics of Alpha Interferon and Anti-Alpha Interferon Neutralizing Antibody in Mice

Antimicrobial Agents and Chemotherapy, 2001-01, Vol.45 (1), p.176-180

2001

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Population-based investigation of relative clearance of digoxin in Japanese neonates and infants by multiple-trough screen analysis

European journal of clinical pharmacology, 2001-04, Vol.57 (1), p.19-24

2001

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Changing the dosing schedule minimizes the disruptive effects of interferon on clock function

Nature medicine, 2001-03, Vol.7 (3), p.356-360

2001

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Chronobiological disturbances with hyperthermia and hypercortisolism induced by chronic mild stress in rats

Behavioural brain research, 2006-10, Vol.173 (2), p.326-330

2006

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Chronic Treatment with Prednisolone Represses the Circadian Oscillation of Clock Gene Expression in Mouse Peripheral Tissues

Molecular endocrinology (Baltimore, Md.), 2006-03, Vol.20 (3), p.573-583

2006

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Alteration of Intrinsic Biological Rhythms during Interferon Treatment and Its Possible Mechanism

Molecular pharmacology, 2002-12, Vol.62 (6), p.1393-1399

2002

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Detection of a drug-drug interaction on population-based phenobarbitone clearance using nonlinear mixed-effects modeling

European journal of clinical pharmacology, 1998-03, Vol.54 (1), p.69-74

1998

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IL-6 receptor is a possible target against growth of metastasized lung tumor cells in the brain

International journal of molecular sciences, 2012-12, Vol.14 (1), p.515-526

2012

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Lithium carbonate

Nihon rinshō, 1999-09, Vol.57 Suppl, p.383

1999

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Influence of feeding schedule on 24-h rhythm of hepatotoxicity induced by acetaminophen in mice

The Journal of pharmacology and experimental therapeutics, 2004-11, Vol.311 (2), p.594-600

2004

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Daily expression of clock genes in whole blood cells in healthy subjects and a patient with circadian rhythm sleep disorder

American journal of physiology. Regulatory, integrative and comparative physiology, 2005-11, Vol.289 (5), p.R1273-R1279

2005

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Influence of age and comedication on steady-state clonazepam serum level-dose ratios in Japanese epileptic patients

Journal of clinical pharmacy and therapeutics, 2001-10, Vol.26 (5), p.375-379

2001

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Clock gene dysfunction in patients with obstructive sleep apnoea syndrome

Effects of herbal extracts on the function of human organic anion-transporting polypeptide OATP-B

Dosing time dependency of doxorubicin-induced cardiotoxicity and bone marrow toxicity in rats

Chrono-drug-delivery focused on biological clock: intra- and inter-individual variability of molecular clock

Accumulation of sorbitol in the sciatic nerve modulates circadian properties of diabetes-induced neuropathic pain hypersensitivity in a diabetic mouse model

Ternary catalytic α-deuteration of carboxylic acids

A molecular mechanism regulating circadian expression of vascular endothelial growth factor in tumor cells

Adrenergic Regulation of Clock Gene Expression in Mouse Liver

Influence of feeding schedule on the chronopharmacological aspects of sodium valproate in mice

Changes in toxicity and effectiveness with timing of drug administration: Implications for drug safety

Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P‐glycoprotein

Population pharmacokinetics of Digoxin in Japanese patients : A 2-compartment pharmacokinetic model

Population pharmacokinetics of haloperidol using Routine clinical pharmacokinetic data in Japanese patients

Effect of Dosing Schedule on Pharmacokinetics of Alpha Interferon and Anti-Alpha Interferon Neutralizing Antibody in Mice

Population-based investigation of relative clearance of digoxin in Japanese neonates and infants by multiple-trough screen analysis

Changing the dosing schedule minimizes the disruptive effects of interferon on clock function

Chronobiological disturbances with hyperthermia and hypercortisolism induced by chronic mild stress in rats

Chronic Treatment with Prednisolone Represses the Circadian Oscillation of Clock Gene Expression in Mouse Peripheral Tissues

Alteration of Intrinsic Biological Rhythms during Interferon Treatment and Its Possible Mechanism

Detection of a drug-drug interaction on population-based phenobarbitone clearance using nonlinear mixed-effects modeling

IL-6 receptor is a possible target against growth of metastasized lung tumor cells in the brain

Lithium carbonate

Influence of feeding schedule on 24-h rhythm of hepatotoxicity induced by acetaminophen in mice

Daily expression of clock genes in whole blood cells in healthy subjects and a patient with circadian rhythm sleep disorder

Influence of age and comedication on steady-state clonazepam serum level-dose ratios in Japanese epileptic patients

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