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Interaction of Cytochrome P450 3A4 and UDP-Glucuronosyltransferase 2B7: Evidence for Protein-Protein Association and Possible Involvement of CYP3A4 J-Helix in the Interaction

Molecular pharmacology, 2009-04, Vol.75 (4), p.956-964

2009

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Inhibition of UDP-glucuronosyltransferase 2b7-catalyzed morphine glucuronidation by ketoconazole: dual mechanisms involving a novel noncompetitive mode

Drug metabolism and disposition, 2006-08, Vol.34 (8), p.1277-1282

2006

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Induction of the hepatic cytochrome P450 2B subfamily by xenobiotics: research history, evolutionary aspect, relation to tumorigenesis, and mechanism

Current drug metabolism, 2006-05, Vol.7 (4), p.397-409

2006

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Modulation of UDP-Glucuronosyltransferase Function by Cytochrome P450: Evidence for the Alteration of UGT2B7-Catalyzed Glucuronidation of Morphine by CYP3A4

Molecular pharmacology, 2005-03, Vol.67 (3), p.665-672

2005

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SIMULTANEOUS EXPRESSION OF GUINEA PIG UDP-GLUCURONOSYLTRANSFERASE 2B21 (UGT2B21) AND 2B22 IN COS-7 CELLS ENHANCES UGT2B21-CATALYZED CHLORAMPHENICOL GLUCURONIDATION

Drug metabolism and disposition, 2004-10, Vol.32 (10), p.1057-1060

2004

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Suppression of Carbonic Anhydrase III mRNA Level by an Aryl Hydrocarbon Receptor Ligand in Primary Cultured Hepatocytes of Rat

Biological and Pharmaceutical Bulletin, 2005, Vol.28(6), pp.1087-1090

2005

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Cytochrome P450 1A1 (CYP1A1) Inhibitor α-Naphthoflavone Interferes with UDP-Glucuronosyltransferase (UGT) Activity in Intact but Not in Permeabilized Hepatic Microsomes from 3-Methylcholanthrene-Treated Rats: Possible Involvement of UGT–P450 Interactions

Biological and Pharmaceutical Bulletin, 2004, Vol.27(1), pp.56-60

2004

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Simultaneous Expression of Guinea Pig UDP-Glucuronosyltransferase 2B21 and 2B22 in COS-7 Cells enhances UDP-Glucuronosyltransferase 2B21-Catalyzed Morphine-6-Glucuronide Formation

Molecular pharmacology, 2001-11, Vol.60 (5), p.1040-1048

2001

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Modulation of UDP-Glucuronosyltransferase 2B7 Function by Cytochrome P450s in Vitro: Differential Effects of CYP1A2, CYP2C9 and CYP3A4

Biological and Pharmaceutical Bulletin, 2005, Vol.28(10), pp.2026-2027

2005

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Reduction of the Toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Mice Using an Antiulcer Drug, Geranylgeranylacetone

Biological and Pharmaceutical Bulletin, 2004, Vol.27(9), pp.1397-1402

2004

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Characteristic glucuronidation pattern of physiologic concentration of morphine in rat brain

Life sciences (1973), 2000-10, Vol.67 (20), p.2453-2464

2000

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Estrogen-Dependent Regulation of the Expression of Hepatic Cyp2b and 3a Isoforms: Assessment Using Aromatase-Deficient Mice

Toxicology and applied pharmacology, 2002-04, Vol.180 (1), p.1-10

2002

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Effects of dioxins on stress-responsive systems and their relevance to toxicity

Journal of dermatological science. Supplement, 2005-04, Vol.1 (1), p.S105-S112

2005

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A Highly Toxic Coplanar Polychlorinated Biphenyl Compound Suppresses Δ5 and Δ6 Desaturase Activities Which Play Key Roles in Arachidonic Acid Synthesis in Rat Liver

Chemical research in toxicology, 1999-12, Vol.12 (12), p.1158-1165

1999

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Metabolism of Drugs of Abuse: Its Contribution to the Toxicity and the Inter-Individual Differences in Drug Sensitivity

Journal of health science (Tokyo, Japan), 2005, Vol.51 (1), p.1-7

2005

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Enhancement of Acetaminophen Cytotoxicity in Selenium-binding Protein-overexpressed COS-1 Cells

DRUG METABOLISM AND PHARMACOKINETICS, 2004, Vol.19 (4), p.290-296

2004

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FORMATION OF HIGHLY ANALGESIC MORPHINE-6-GLUCURONIDE FOLLOWING PHYSIOLOGIC CONCENTRATION OF MORPHINE IN HUMAN BRAIN

The Journal of Toxicological Sciences, 2003, Vol.28(5), pp.395-401

2003

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Liver Proteins that are Sensitive to a Dioxin-Like Toxic Compound, Coplanar Polychlorinated Biphenyl, 3,3',4,4',5-Pentachlorobiphenyl

Journal of health science (Tokyo, Japan), 2002-01, Vol.48 (2), p.97-105

2002

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A highly toxic PCB produces unusual changes in the fatty acid composition of rat liver

Toxicology letters, 1997-04, Vol.91 (2), p.99-104

1997

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Effect of a ligand selective for peripheral benzodiazepine receptors on the expression of rat hepatic P-450 cytochromes: assessment of the effect in vivo and in a hepatocyte culture system

Drug metabolism and disposition, 1999-11, Vol.27 (11), p.1242

1999

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Suppression of Carbonic Anhydrase III in Rat Liver by a Dioxin-Related Toxic Compound, Coplanar Polychlorinated Biphenyl, 3,3′,4,4′,5-Pentachlorobiphenyl

Archives of biochemistry and biophysics, 2000-08, Vol.380 (1), p.159-164

2000

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FORMATION OF HIGHLY ANALGESIC MORPHINE-6-GLUCURONIDE FOLLOWING PHYSIOLOGIC CONCENTRATION OF MORPHINE IN HUMAN BRAIN

Journal of toxicological sciences, 2003-12, Vol.28 (5), p.395-401

2003

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Sequence analyses of CYP2B genes and catalytic profiles for P450s in Qdj:Sprague-dawley rats that lack response to the phenobarbital-mediated induction of CYP2B2

The Journal of pharmacology and experimental therapeutics, 2000-12, Vol.295 (3), p.986

2000

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The Induction of Hepatic Selenium-Binding Protein by Aryl Hydrocarbon (Ah)-Receptor Ligands in Rats

Journal of health science (Tokyo, Japan), 2002-01, Vol.48 (1), p.62-68

2002

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Changes in the hepatic glutathione peroxidase redox system produced by coplanar polychlorinated biphenyls in Ah-responsive and -less-responsive strains of mice: mechanism and implications for toxicity

Environmental toxicology and pharmacology, 1997-09, Vol.3 (4), p.267-275

1997

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Interaction of Cytochrome P450 3A4 and UDP-Glucuronosyltransferase 2B7: Evidence for Protein-Protein Association and Possible Involvement of CYP3A4 J-Helix in the Interaction

Inhibition of UDP-glucuronosyltransferase 2b7-catalyzed morphine glucuronidation by ketoconazole: dual mechanisms involving a novel noncompetitive mode

Induction of the hepatic cytochrome P450 2B subfamily by xenobiotics: research history, evolutionary aspect, relation to tumorigenesis, and mechanism

Modulation of UDP-Glucuronosyltransferase Function by Cytochrome P450: Evidence for the Alteration of UGT2B7-Catalyzed Glucuronidation of Morphine by CYP3A4

SIMULTANEOUS EXPRESSION OF GUINEA PIG UDP-GLUCURONOSYLTRANSFERASE 2B21 (UGT2B21) AND 2B22 IN COS-7 CELLS ENHANCES UGT2B21-CATALYZED CHLORAMPHENICOL GLUCURONIDATION

Suppression of Carbonic Anhydrase III mRNA Level by an Aryl Hydrocarbon Receptor Ligand in Primary Cultured Hepatocytes of Rat

Cytochrome P450 1A1 (CYP1A1) Inhibitor α-Naphthoflavone Interferes with UDP-Glucuronosyltransferase (UGT) Activity in Intact but Not in Permeabilized Hepatic Microsomes from 3-Methylcholanthrene-Treated Rats: Possible Involvement of UGT–P450 Interactions

Simultaneous Expression of Guinea Pig UDP-Glucuronosyltransferase 2B21 and 2B22 in COS-7 Cells enhances UDP-Glucuronosyltransferase 2B21-Catalyzed Morphine-6-Glucuronide Formation

Modulation of UDP-Glucuronosyltransferase 2B7 Function by Cytochrome P450s in Vitro: Differential Effects of CYP1A2, CYP2C9 and CYP3A4

Reduction of the Toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Mice Using an Antiulcer Drug, Geranylgeranylacetone

Characteristic glucuronidation pattern of physiologic concentration of morphine in rat brain

Estrogen-Dependent Regulation of the Expression of Hepatic Cyp2b and 3a Isoforms: Assessment Using Aromatase-Deficient Mice

Effects of dioxins on stress-responsive systems and their relevance to toxicity

A Highly Toxic Coplanar Polychlorinated Biphenyl Compound Suppresses Δ5 and Δ6 Desaturase Activities Which Play Key Roles in Arachidonic Acid Synthesis in Rat Liver

Metabolism of Drugs of Abuse: Its Contribution to the Toxicity and the Inter-Individual Differences in Drug Sensitivity

Enhancement of Acetaminophen Cytotoxicity in Selenium-binding Protein-overexpressed COS-1 Cells

FORMATION OF HIGHLY ANALGESIC MORPHINE-6-GLUCURONIDE FOLLOWING PHYSIOLOGIC CONCENTRATION OF MORPHINE IN HUMAN BRAIN

Liver Proteins that are Sensitive to a Dioxin-Like Toxic Compound, Coplanar Polychlorinated Biphenyl, 3,3',4,4',5-Pentachlorobiphenyl

A highly toxic PCB produces unusual changes in the fatty acid composition of rat liver

Effect of a ligand selective for peripheral benzodiazepine receptors on the expression of rat hepatic P-450 cytochromes: assessment of the effect in vivo and in a hepatocyte culture system

Suppression of Carbonic Anhydrase III in Rat Liver by a Dioxin-Related Toxic Compound, Coplanar Polychlorinated Biphenyl, 3,3′,4,4′,5-Pentachlorobiphenyl

FORMATION OF HIGHLY ANALGESIC MORPHINE-6-GLUCURONIDE FOLLOWING PHYSIOLOGIC CONCENTRATION OF MORPHINE IN HUMAN BRAIN

Sequence analyses of CYP2B genes and catalytic profiles for P450s in Qdj:Sprague-dawley rats that lack response to the phenobarbital-mediated induction of CYP2B2

The Induction of Hepatic Selenium-Binding Protein by Aryl Hydrocarbon (Ah)-Receptor Ligands in Rats

Changes in the hepatic glutathione peroxidase redox system produced by coplanar polychlorinated biphenyls in Ah-responsive and -less-responsive strains of mice: mechanism and implications for toxicity

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