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Adoptive T cell immunotherapy for cancer

Rambam Maimonides medical journal, 2015-01, Vol.6 (1), p.e0004-e0004

2015

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Selective Effects of mTOR Inhibitor Sirolimus on Naïve and CMV-Specific T Cells Extending Its Applicable Range Beyond Immunosuppression

Frontiers in immunology, 2018-12, Vol.9, p.2953-2953

2018

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Ovarian Cancer-associated Ascites Demonstrates Altered Immune Environment: Implications for Antitumor Immunity

Anticancer research, 2009-08, Vol.29 (8), p.2875-2884

2009

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396 Artificial Immune Modulation (AIM) nanoparticles expand antigen specific CD8 T cells from both naïve and memory T cell populations

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A444-A444

2023

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Molecular Identification of GD3 as a Suppressor of the Innate Immune Response in Ovarian Cancer

Cancer research (Chicago, Ill.), 2012-08, Vol.72 (15), p.3744-3752

2012

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1139 Efficacy of injectable antigen presenting nanoparticles (AIM INJ), in solid tumor models

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1253-A1253

2023

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202 In vivo and in vitro characterization of AIM ACT, a novel nanoparticle-based technology, expanded MART-1 specific T cells

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A213-A213

2021

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395 Enhancement of bispecific T cell engagers (bispecific TCE) killing potency in AML with the neximmune artificial immune modulation (AIM™) adoptive cell therapy (ACT) T cells

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A443-A443

2023

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Dietary fatty acids modulate antigen presentation to hepatic NKT cells in nonalcoholic fatty liver disease[S]

Journal of lipid research, 2010-07, Vol.51 (7), p.1696-1703

2010

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AIM™ platform: A new immunotherapy approach for viral diseases

Frontiers in medicine, 2022-12, Vol.9, p.1070529-1070529

2022

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T-cell memory responses elicited by yellow fever vaccine are targeted to overlapping epitopes containing multiple HLA-I and -II binding motifs

PLoS neglected tropical diseases, 2013-01, Vol.7 (1), p.e1938-e1938

2013

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Dynamic regulation of functionally distinct virus-specific T cells

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (8), p.3669-3674

2010

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Heat shock protein 70/peptide complexes: potent mediators for the generation of antiviral T cells particularly with regard to low precursor frequencies

Journal of translational medicine, 2011-10, Vol.9 (1), p.175-175, Article 175

2011

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Ascites Specific Inhibition of CD1d-Mediated Activation of Natural Killer T Cells

Clinical cancer research, 2008-12, Vol.14 (23), p.7652-7658

2008

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Differential Innate Immune Cell Activation and Proinflammatory Response in Anaplasma phagocytophilum Infection

Infection and Immunity, 2007-06, Vol.75 (6), p.3124-3130

2007

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Decline of influenza-specific CD8+ T cell repertoire in healthy geriatric donors

Immunity & ageing, 2011-08, Vol.8 (1), p.6-6, Article 6

2011

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Development of an Artificial-Antigen-Presenting-Cell-Based Assay for the Detection of Low-Frequency Virus-Specific CD8+ T Cells in Whole Blood, with Application for Measles Virus

Clinical and Vaccine Immunology, 2009-07, Vol.16 (7), p.1066-1073

2009

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Enrichment and Expansion with Nanoscale Artificial Antigen Presenting Cells for Adoptive Immunotherapy

ACS nano, 2015-07, Vol.9 (7), p.6861-6871

2015

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An analysis of a first-in-human study of NEXI-001 donor-derived antigen-specific CD8+ T-cell treatment of relapsed AML after allogeneic hematopoietic cell transplantation (HCT)

Journal of clinical oncology, 2023-06, Vol.41 (16_suppl), p.7043-7043

2023

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Rapid Expansion of Highly Functional Antigen-Specific T Cells from Patients with Melanoma by Nanoscale Artificial Antigen-Presenting Cells

Clinical cancer research, 2020-07, Vol.26 (13), p.3384-3396

2020

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Multi-Antigen Primed T Cells Promote Apoptosis of Acute Myeloid Leukemia (AML)

Blood, 2021-11, Vol.138 (Supplement 1), p.4794-4794

2021

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Phase 1/2 Study of Nexi-002 Autologous Multi-Antigen-Specific CD8+ T Cells for the Treatment of Relapsed or Refractory Multiple Myeloma

Blood, 2021-11, Vol.138 (Supplement 1), p.2824-2824

2021

Volltextzugriff (PDF)

Generation and Purification of CD8+ Melan-A-specific Cytotoxic T Lymphocytes for Adoptive Transfer in Tumor Immunotherapy

Clinical cancer research, 2000-05, Vol.6 (5), p.1997-2005

2000

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Soluble MHC class I complexes for targeted immunotherapy

Life sciences (1973), 2018-09, Vol.209, p.255-258

2018

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Cord blood–derived T cells allow the generation of a more naïve tumor‐reactive cytotoxic T‐cell phenotype

Transfusion (Philadelphia, Pa.), 2018-01, Vol.58 (1), p.88-99

2018

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Adoptive T cell immunotherapy for cancer

Selective Effects of mTOR Inhibitor Sirolimus on Naïve and CMV-Specific T Cells Extending Its Applicable Range Beyond Immunosuppression

Ovarian Cancer-associated Ascites Demonstrates Altered Immune Environment: Implications for Antitumor Immunity

396 Artificial Immune Modulation (AIM) nanoparticles expand antigen specific CD8 T cells from both naïve and memory T cell populations

Molecular Identification of GD3 as a Suppressor of the Innate Immune Response in Ovarian Cancer

1139 Efficacy of injectable antigen presenting nanoparticles (AIM INJ), in solid tumor models

202 In vivo and in vitro characterization of AIM ACT, a novel nanoparticle-based technology, expanded MART-1 specific T cells

395 Enhancement of bispecific T cell engagers (bispecific TCE) killing potency in AML with the neximmune artificial immune modulation (AIM™) adoptive cell therapy (ACT) T cells

Dietary fatty acids modulate antigen presentation to hepatic NKT cells in nonalcoholic fatty liver disease[S]

AIM™ platform: A new immunotherapy approach for viral diseases

T-cell memory responses elicited by yellow fever vaccine are targeted to overlapping epitopes containing multiple HLA-I and -II binding motifs

Dynamic regulation of functionally distinct virus-specific T cells

Heat shock protein 70/peptide complexes: potent mediators for the generation of antiviral T cells particularly with regard to low precursor frequencies

Ascites Specific Inhibition of CD1d-Mediated Activation of Natural Killer T Cells

Differential Innate Immune Cell Activation and Proinflammatory Response in Anaplasma phagocytophilum Infection

Decline of influenza-specific CD8+ T cell repertoire in healthy geriatric donors

Development of an Artificial-Antigen-Presenting-Cell-Based Assay for the Detection of Low-Frequency Virus-Specific CD8+ T Cells in Whole Blood, with Application for Measles Virus

Enrichment and Expansion with Nanoscale Artificial Antigen Presenting Cells for Adoptive Immunotherapy

An analysis of a first-in-human study of NEXI-001 donor-derived antigen-specific CD8+ T-cell treatment of relapsed AML after allogeneic hematopoietic cell transplantation (HCT)

Rapid Expansion of Highly Functional Antigen-Specific T Cells from Patients with Melanoma by Nanoscale Artificial Antigen-Presenting Cells

Multi-Antigen Primed T Cells Promote Apoptosis of Acute Myeloid Leukemia (AML)

Phase 1/2 Study of Nexi-002 Autologous Multi-Antigen-Specific CD8+ T Cells for the Treatment of Relapsed or Refractory Multiple Myeloma

Generation and Purification of CD8+ Melan-A-specific Cytotoxic T Lymphocytes for Adoptive Transfer in Tumor Immunotherapy

Soluble MHC class I complexes for targeted immunotherapy

Cord blood–derived T cells allow the generation of a more naïve tumor‐reactive cytotoxic T‐cell phenotype

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