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Distinguishing genetic correlation from causation across 52 diseases and complex traits

Nature genetics, 2018-12, Vol.50 (12), p.1728-1734

2018

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The distribution of common-variant effect sizes

Nature genetics, 2021-08, Vol.53 (8), p.1243-1249

O’Connor, Luke J.

2021

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Quantifying genetic effects on disease mediated by assayed gene expression levels

Nature genetics, 2020-06, Vol.52 (6), p.626-633

2020

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Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity

Nature genetics, 2022-06, Vol.54 (6), p.827-836

2022

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Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection

Nature communications, 2019-02, Vol.10 (1), p.790-790, Article 790

2019

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Extreme Polygenicity of Complex Traits Is Explained by Negative Selection

American journal of human genetics, 2019-09, Vol.105 (3), p.456-476

2019

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Functionally informed fine-mapping and polygenic localization of complex trait heritability

Nature genetics, 2020-12, Vol.52 (12), p.1355-1363

2020

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Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank

Journal of allergy and clinical immunology, 2020-02, Vol.145 (2), p.537-549

2020

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Shared components of heritability across genetically correlated traits

American journal of human genetics, 2022-06, Vol.109 (6), p.989-1006

2022

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Polygenic architecture of rare coding variation across 394,783 exomes

Nature (London), 2023-02, Vol.614 (7948), p.492-499

2023

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Extremely sparse models of linkage disequilibrium in ancestrally diverse association studies

Nature genetics, 2023-09, Vol.55 (9), p.1494-1502

2023

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Role of multiparametric prostate MRI in the management of prostate cancer

World journal of urology, 2021-03, Vol.39 (3), p.651-659

2021

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HAPNEST: efficient, large-scale generation and evaluation of synthetic datasets for genotypes and phenotypes

Bioinformatics (Oxford, England), 2023-09, Vol.39 (9)

2023

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Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits

Nature genetics, 2018-07, Vol.50 (7), p.1041-1047

2018

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Partitioning gene-mediated disease heritability without eQTLs

American journal of human genetics, 2022-03, Vol.109 (3), p.405-416

2022

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Supramolecular Tuning of Exciton Transport in Pi-Peptide Assemblies

Journal of physical chemistry. C, 2023-01, Vol.127 (3), p.1310-1319

2023

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Functional Architectures of Local and Distal Regulation of Gene Expression in Multiple Human Tissues

American journal of human genetics, 2017-04, Vol.100 (4), p.605-616

2017

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High-dimensional phenotyping to define the genetic basis of cellular morphology

Nature communications, 2024-01, Vol.15 (1), p.347-12, Article 347

2024

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Making a case “for” focal therapy of the prostate in intermediate risk prostate cancer: current perspective and ongoing trials

World journal of urology, 2021-03, Vol.39 (3), p.729-739

2021

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‘Case of the Month’ from the National Cancer Institute, Bethesda, MD, USA: investigating genetic aberrations in a patient with high‐risk prostate cancer

BJU international, 2021-02, Vol.127 (2), p.171-174

2021

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Exciton Transfer Between Extended Electronic States in Conjugated Inter-Polyelectrolyte Complexes

ACS applied materials & interfaces, 2024-01, Vol.16 (16), p.19995-20010

2024

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The Risk of Prostate Cancer Progression in Active Surveillance Patients with Bilateral Disease Detected by Combined Magnetic Resonance Imaging-Fusion and Systematic Biopsy

The Journal of urology, 2021-11, Vol.206 (5), p.1157-1165

2021

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What is an appropriate dose of voriconazole for the treatment of aspergillosis in African grey parrots (Psittacus erithacus)?

Veterinary record, 2018-07, Vol.183 (4), p.131-132

2018

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Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk

Nature genetics, 2018-10, Vol.50 (10), p.1483-1493

2018

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Magnetic Resonance Imaging-Targeted and Systematic Biopsy for Detection of Grade Progression in Patients on Active Surveillance for Prostate Cancer

The Journal of urology, 2021-05, Vol.205 (5), p.1352-1360

2021

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Distinguishing genetic correlation from causation across 52 diseases and complex traits

The distribution of common-variant effect sizes

Quantifying genetic effects on disease mediated by assayed gene expression levels

Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity

Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection

Extreme Polygenicity of Complex Traits Is Explained by Negative Selection

Functionally informed fine-mapping and polygenic localization of complex trait heritability

Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank

Shared components of heritability across genetically correlated traits

Polygenic architecture of rare coding variation across 394,783 exomes

Extremely sparse models of linkage disequilibrium in ancestrally diverse association studies

Role of multiparametric prostate MRI in the management of prostate cancer

HAPNEST: efficient, large-scale generation and evaluation of synthetic datasets for genotypes and phenotypes

Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits

Partitioning gene-mediated disease heritability without eQTLs

Supramolecular Tuning of Exciton Transport in Pi-Peptide Assemblies

Functional Architectures of Local and Distal Regulation of Gene Expression in Multiple Human Tissues

High-dimensional phenotyping to define the genetic basis of cellular morphology

Making a case “for” focal therapy of the prostate in intermediate risk prostate cancer: current perspective and ongoing trials

‘Case of the Month’ from the National Cancer Institute, Bethesda, MD, USA: investigating genetic aberrations in a patient with high‐risk prostate cancer

Exciton Transfer Between Extended Electronic States in Conjugated Inter-Polyelectrolyte Complexes

The Risk of Prostate Cancer Progression in Active Surveillance Patients with Bilateral Disease Detected by Combined Magnetic Resonance Imaging-Fusion and Systematic Biopsy

What is an appropriate dose of voriconazole for the treatment of aspergillosis in African grey parrots (Psittacus erithacus)?

Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk

Magnetic Resonance Imaging-Targeted and Systematic Biopsy for Detection of Grade Progression in Patients on Active Surveillance for Prostate Cancer

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