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P53-dependent upregulation of neutral sphingomyelinase-2: role in doxorubicin-induced growth arrest

Cell death & disease, 2015-10, Vol.6 (10), p.e1947-e1947

2015

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Alkaline ceramidase 3 deficiency aggravates colitis and colitis-associated tumorigenesis in mice by hyperactivating the innate immune system

Cell death & disease, 2016-03, Vol.7 (3), p.e2124-e2124

2016

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Selective hydrolysis of a mitochondrial pool of sphingomyelin induces apoptosis

The FASEB journal, 2001-12, Vol.15 (14), p.2669-2679

2001

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P38 delta MAPK promotes breast cancer progression and lung metastasis by enhancing cell proliferation and cell detachment

Oncogene, 2017-11, Vol.36 (47), p.6649-6657

2017

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Programmed Cell Death Induced by Ceramide

Science (American Association for the Advancement of Science), 1993-03, Vol.259 (5102), p.1769-1771

1993

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Defining a role for sphingosine kinase 1 in p53-dependent tumors

Oncogene, 2012-03, Vol.31 (9), p.1166-1175

2012

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Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide

The Journal of biological chemistry, 1993-12, Vol.268 (35), p.26226-26232

1993

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Role of ceramide-activated protein phosphatase in ceramide-mediated signal transduction

The Journal of biological chemistry, 1994-07, Vol.269 (30), p.19605-19609

1994

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Bcl-2 Interrupts the Ceramide-Mediated Pathway of Cell Death

Proceedings of the National Academy of Sciences - PNAS, 1996-05, Vol.93 (11), p.5325-5328

1996

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Tumor necrosis factor-alpha (TNF-alpha) signal transduction through ceramide. Dissociation of growth inhibitory effects of TNF-alpha from activation of nuclear factor-kappa B

The Journal of biological chemistry, 1993-08, Vol.268 (24), p.17762-17766

1993

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Regulation of Cyclin-Dependent Kinase 2 Activity by Ceramide

Experimental cell research, 2000-12, Vol.261 (2), p.303-311

2000

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De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1

The Journal of biological chemistry, 2002-04, Vol.277 (15), p.12587-12595

2002

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Selective regulation of expression of protein kinase C (PKC) isoenzymes in multidrug-resistant MCF-7 cells. Functional significance of enhanced expression of PKC alpha

The Journal of biological chemistry, 1993-01, Vol.268 (1), p.658-664

1993

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Ceramide and the eukaryotic stress response

Biochemical Society transactions, 1997-11, Vol.25 (4), p.1171

1997

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Retinoblastoma Gene Product as a Downstream Target for a Ceramide-Dependent Pathway of Growth Arrest

Proceedings of the National Academy of Sciences - PNAS, 1995-02, Vol.92 (5), p.1347-1351

1995

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Role of Human Sphingosine-1-phosphate Phosphatase 1 in the Regulation of Intra- and Extracellular Sphingosine-1-phosphate Levels and Cell Viability

The Journal of biological chemistry, 2003-09, Vol.278 (36), p.34541-34547

2003

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Effects of sphingosine and other sphingolipids on protein kinase C

Methods in Enzymology, 2000, Vol.312, p.361-373

2000

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Rapid Shortening of Telomere Length in Response to Ceramide Involves the Inhibition of Telomere Binding Activity of Nuclear Glyceraldehyde-3-phosphate Dehydrogenase

The Journal of biological chemistry, 2004-02, Vol.279 (7), p.6152-6162

2004

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Down-regulation of sphingosine kinase-1 by DNA damage: dependence on proteases and p53

The Journal of biological chemistry, 2004-05, Vol.279 (19), p.20546-20554

2004

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Glutathione Regulation of Neutral Sphingomyelinase in Tumor Necrosis Factor-α-induced Cell Death

The Journal of biological chemistry, 1998-05, Vol.273 (18), p.11313-11320

1998

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Identification of a defect in the phospholipase D/diacylglycerol pathway in cellular senescence

The Journal of biological chemistry, 1994-10, Vol.269 (42), p.26040-26044

1994

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Thioredoxin Peroxidase Is a Novel Inhibitor of Apoptosis with a Mechanism Distinct from That of Bcl-2

The Journal of biological chemistry, 1997-12, Vol.272 (49), p.30615-30618

1997

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Ceramide: an intracellular signal for apoptosis

Trends in Biochemical Sciences, 1995-02, Vol.20 (2), p.73-77

1995

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Cloning of an alkaline ceramidase from Saccharomyces cerevisiae. An enzyme with reverse (CoA-independent) ceramide synthase activity

The Journal of biological chemistry, 2000-03, Vol.275 (10), p.6876-6884

2000

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Transcriptional regulation of protein kinase C by 1,25-dihydroxyvitamin D3 in HL-60 cells

The Journal of biological chemistry, 1990-02, Vol.265 (4), p.2370-2374

1990

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P53-dependent upregulation of neutral sphingomyelinase-2: role in doxorubicin-induced growth arrest

Alkaline ceramidase 3 deficiency aggravates colitis and colitis-associated tumorigenesis in mice by hyperactivating the innate immune system

Selective hydrolysis of a mitochondrial pool of sphingomyelin induces apoptosis

P38 delta MAPK promotes breast cancer progression and lung metastasis by enhancing cell proliferation and cell detachment

Programmed Cell Death Induced by Ceramide

Defining a role for sphingosine kinase 1 in p53-dependent tumors

Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide

Role of ceramide-activated protein phosphatase in ceramide-mediated signal transduction

Bcl-2 Interrupts the Ceramide-Mediated Pathway of Cell Death

Tumor necrosis factor-alpha (TNF-alpha) signal transduction through ceramide. Dissociation of growth inhibitory effects of TNF-alpha from activation of nuclear factor-kappa B

Regulation of Cyclin-Dependent Kinase 2 Activity by Ceramide

De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1

Selective regulation of expression of protein kinase C (PKC) isoenzymes in multidrug-resistant MCF-7 cells. Functional significance of enhanced expression of PKC alpha

Ceramide and the eukaryotic stress response

Retinoblastoma Gene Product as a Downstream Target for a Ceramide-Dependent Pathway of Growth Arrest

Role of Human Sphingosine-1-phosphate Phosphatase 1 in the Regulation of Intra- and Extracellular Sphingosine-1-phosphate Levels and Cell Viability

Effects of sphingosine and other sphingolipids on protein kinase C

Rapid Shortening of Telomere Length in Response to Ceramide Involves the Inhibition of Telomere Binding Activity of Nuclear Glyceraldehyde-3-phosphate Dehydrogenase

Down-regulation of sphingosine kinase-1 by DNA damage: dependence on proteases and p53

Glutathione Regulation of Neutral Sphingomyelinase in Tumor Necrosis Factor-α-induced Cell Death

Identification of a defect in the phospholipase D/diacylglycerol pathway in cellular senescence

Thioredoxin Peroxidase Is a Novel Inhibitor of Apoptosis with a Mechanism Distinct from That of Bcl-2

Ceramide: an intracellular signal for apoptosis

Cloning of an alkaline ceramidase from Saccharomyces cerevisiae. An enzyme with reverse (CoA-independent) ceramide synthase activity

Transcriptional regulation of protein kinase C by 1,25-dihydroxyvitamin D3 in HL-60 cells

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