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Analgesic Mechanisms of Antidepressants for Neuropathic Pain

International journal of molecular sciences, 2017-11, Vol.18 (11), p.2483

Obata, Hideaki

2017

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Strategies to Treat Chronic Pain and Strengthen Impaired Descending Noradrenergic Inhibitory System

International journal of molecular sciences, 2019-02, Vol.20 (4), p.822

2019

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Repeated Administration of Amitriptyline in Neuropathic Pain: Modulation of the Noradrenergic Descending Inhibitory System

Anesthesia and analgesia, 2017-10, Vol.125 (4), p.1281-1288

2017

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Repeated Administration of Duloxetine Suppresses Neuropathic Pain by Accumulating Effects of Noradrenaline in the Spinal Cord

Anesthesia and analgesia, 2018-01, Vol.126 (1), p.298-307

2018

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Spinal Activation of Tropomyosin Receptor Kinase-B Recovers the Impaired Endogenous Analgesia in Neuropathic Pain Rats

Anesthesia and analgesia, 2019-08, Vol.129 (2), p.578-586

2019

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An increase in spinal cord noradrenaline is a major contributor to the antihyperalgesic effect of antidepressants after peripheral nerve injury in the rat

Pain (Amsterdam), 2012-05, Vol.153 (5), p.990-997

2012

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Spinal dopaminergic involvement in the antihyperalgesic effect of antidepressants in a rat model of neuropathic pain

Neuroscience letters, 2017-05, Vol.649, p.116-123

2017

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Antihyperalgesic effect of duloxetine and amitriptyline in rats after peripheral nerve injury: Influence of descending noradrenergic plasticity

Neuroscience letters, 2015-08, Vol.602, p.62-67

2015

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Randomized active-controlled study of a single preoperative administration of duloxetine to treat postoperative pain and numbness after posterior lumbar interbody fusion surgery

Medicine (Baltimore), 2022-12, Vol.101 (50), p.e32306-e32306

2022

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Rat model of attention-deficit hyperactivity disorder exhibits delayed recovery from acute incisional pain due to impaired descending noradrenergic inhibition

Scientific reports, 2023-04, Vol.13 (1), p.5526-5526, Article 5526

2023

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The Antihyperalgesic Effects of Intrathecal Bupropion, a Dopamine and Noradrenaline Reuptake Inhibitor, in a Rat Model of Neuropathic Pain

Anesthesia and analgesia, 2015-02, Vol.120 (2), p.460-466

2015

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Peripheral Nerve Injury Reduces Analgesic Effectsof Systemic Morphine via Spinal 5-Hydroxytryptamine 3 Receptors

Anesthesiology (Philadelphia), 2014-08, Vol.121 (2), p.362-371

2014

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Tropomyosin Receptor Kinase B Receptor Activation in the Locus Coeruleus Restores Impairment of Endogenous Analgesia at a Late Stage Following Nerve Injury in Rats

The journal of pain, 2019-05, Vol.20 (5), p.600-609

2019

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Activation of astrocytes in the spinal cord contributes to the development of bilateral allodynia after peripheral nerve injury in rats

Brain research, 2010-12, Vol.1363, p.72-80

2010

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Gabapentin Acts within the Locus Coeruleus to Alleviate Neuropathic Pain

Anesthesiology (Philadelphia), 2008-12, Vol.109 (6), p.1077-1084

2008

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Antihypersensitivity Effects of Tramadol Hydrochloride in a Rat Model of Postoperative Pain

Anesthesia and analgesia, 2012-08, Vol.115 (2), p.443-449

2012

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A randomized placebo-controlled study of preoperative pregabalin for postoperative analgesia in patients with spinal surgery

Journal of clinical anesthesia, 2016-06, Vol.31, p.149-153

2016

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Spinal Glial Activation Contributes to Postoperative Mechanical Hypersensitivity in the Rat

The journal of pain, 2006-11, Vol.7 (11), p.816-822

2006

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Brain morphological alternation in chronic pain patients with neuropathic characteristics

Molecular pain, 2016, Vol.12, p.174480691665240

2016

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The antiallodynic effect of intrathecal tianeptine is exerted by increased serotonin and norepinephrine in the spinal dorsal horn

Neuroscience letters, 2014-11, Vol.583, p.103-107

2014

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The influence of manipulations to alter ambient GABA concentrations on the hypnotic and immobilizing actions produced by sevoflurane, propofol, and midazolam

Neuropharmacology, 2011-07, Vol.61 (1), p.172-180

2011

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Peripheral 5-HT2A receptor antagonism attenuates primary thermal hyperalgesia and secondary mechanical allodynia after thermal injury in rats

Pain (Amsterdam), 2006-05, Vol.122 (1-2), p.130-136

2006

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Milnacipran Inhibits Glutamatergic N-Methyl-D-Aspartate Receptor Activity in Spinal Dorsal Horn Neurons

Molecular pain, 2012-06, Vol.8 (1), p.45-45

2012

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Lack of analgesic efficacy of spinal ondansetron on thermal and mechanical hypersensitivity following spinal nerve ligation in the rat

Brain research, 2010-09, Vol.1352, p.83-93

2010

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The Monoamine-Mediated Antiallodynic Effects of Intrathecally Administered Milnacipran, a Serotonin Noradrenaline Reuptake Inhibitor, in a Rat Model of Neuropathic Pain

Anesthesia and analgesia, 2005-05, Vol.100 (5), p.1406-1410

2005

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Analgesic Mechanisms of Antidepressants for Neuropathic Pain

Strategies to Treat Chronic Pain and Strengthen Impaired Descending Noradrenergic Inhibitory System

Repeated Administration of Amitriptyline in Neuropathic Pain: Modulation of the Noradrenergic Descending Inhibitory System

Repeated Administration of Duloxetine Suppresses Neuropathic Pain by Accumulating Effects of Noradrenaline in the Spinal Cord

Spinal Activation of Tropomyosin Receptor Kinase-B Recovers the Impaired Endogenous Analgesia in Neuropathic Pain Rats

An increase in spinal cord noradrenaline is a major contributor to the antihyperalgesic effect of antidepressants after peripheral nerve injury in the rat

Spinal dopaminergic involvement in the antihyperalgesic effect of antidepressants in a rat model of neuropathic pain

Antihyperalgesic effect of duloxetine and amitriptyline in rats after peripheral nerve injury: Influence of descending noradrenergic plasticity

Randomized active-controlled study of a single preoperative administration of duloxetine to treat postoperative pain and numbness after posterior lumbar interbody fusion surgery

Rat model of attention-deficit hyperactivity disorder exhibits delayed recovery from acute incisional pain due to impaired descending noradrenergic inhibition

The Antihyperalgesic Effects of Intrathecal Bupropion, a Dopamine and Noradrenaline Reuptake Inhibitor, in a Rat Model of Neuropathic Pain

Peripheral Nerve Injury Reduces Analgesic Effectsof Systemic Morphine via Spinal 5-Hydroxytryptamine 3 Receptors

Tropomyosin Receptor Kinase B Receptor Activation in the Locus Coeruleus Restores Impairment of Endogenous Analgesia at a Late Stage Following Nerve Injury in Rats

Activation of astrocytes in the spinal cord contributes to the development of bilateral allodynia after peripheral nerve injury in rats

Gabapentin Acts within the Locus Coeruleus to Alleviate Neuropathic Pain

Antihypersensitivity Effects of Tramadol Hydrochloride in a Rat Model of Postoperative Pain

A randomized placebo-controlled study of preoperative pregabalin for postoperative analgesia in patients with spinal surgery

Spinal Glial Activation Contributes to Postoperative Mechanical Hypersensitivity in the Rat

Brain morphological alternation in chronic pain patients with neuropathic characteristics

The antiallodynic effect of intrathecal tianeptine is exerted by increased serotonin and norepinephrine in the spinal dorsal horn

The influence of manipulations to alter ambient GABA concentrations on the hypnotic and immobilizing actions produced by sevoflurane, propofol, and midazolam

Peripheral 5-HT2A receptor antagonism attenuates primary thermal hyperalgesia and secondary mechanical allodynia after thermal injury in rats

Milnacipran Inhibits Glutamatergic N-Methyl-D-Aspartate Receptor Activity in Spinal Dorsal Horn Neurons

Lack of analgesic efficacy of spinal ondansetron on thermal and mechanical hypersensitivity following spinal nerve ligation in the rat

The Monoamine-Mediated Antiallodynic Effects of Intrathecally Administered Milnacipran, a Serotonin Noradrenaline Reuptake Inhibitor, in a Rat Model of Neuropathic Pain

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