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Christopher T. Walsh (1944-2023)

Science (American Association for the Advancement of Science), 2023-02, Vol.379 (6634), p.762-762

O'Halloran, Thomas V

2023

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Dynamic zinc fluxes regulate meiotic progression in Caenorhabditis elegans

Biology of reproduction, 2022-08, Vol.107 (2), p.406-418

2022

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Arsenoplatin‑1 Is a Dual Pharmacophore Anticancer Agent

Journal of the American Chemical Society, 2019-04, Vol.141 (16), p.6453-6457

2019

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Allosteric transcriptional regulation via changes in the overall topology of the core promoter

Science (American Association for the Advancement of Science), 2015-08, Vol.349 (6250), p.877-881

2015

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CueR activates transcription through a DNA distortion mechanism

Nature chemical biology, 2021-01, Vol.17 (1), p.57-64

2021

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Quantitative mapping of zinc fluxes in the mammalian egg reveals the origin of fertilization-induced zinc sparks

Nature chemistry, 2015-02, Vol.7 (2), p.130-139

2015

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Patient-Derived Tumor Xenografts Are Susceptible to Formation of Human Lymphocytic Tumors

Neoplasia (New York, N.Y.), 2015-09, Vol.17 (9), p.735-741

2015

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Activation of superoxide dismutases: Putting the metal to the pedal

Biochimica et biophysica acta, 2006-07, Vol.1763 (7), p.747-758

2006

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A place for thioether chemistry in cellular copper ion recognition and trafficking

Nature chemical biology, 2008-03, Vol.4 (3), p.148-151

2008

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Molecular Pathways: Revisiting Glycogen Synthase Kinase-3β as a Target for the Treatment of Cancer

Clinical cancer research, 2017-04, Vol.23 (8), p.1891-1897

2017

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A new role for Zinc limitation in bacterial pathogenicity: modulation of α-hemolysin from uropathogenic Escherichia coli

Scientific reports, 2018-04, Vol.8 (1), p.6535-11, Article 6535

2018

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The bacterial multidrug resistance regulator BmrR distorts promoter DNA to activate transcription

Nature communications, 2020-12, Vol.11 (1), p.6284-6284, Article 6284

2020

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The zinc spark is an inorganic signature of human egg activation

Scientific reports, 2016-04, Vol.6 (1), p.24737-24737, Article 24737

2016

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Quantitative imaging approaches to understanding biological processing of metal ions

Current opinion in chemical biology, 2022-08, Vol.69, p.102152-102152, Article 102152

2022

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Zinc availability regulates exit from meiosis in maturing mammalian oocytes

Nature chemical biology, 2010-09, Vol.6 (9), p.674-681

2010

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Structural and mechanistic basis of zinc regulation across the E. coli Zur regulon

PLoS biology, 2014-11, Vol.12 (11), p.e1001987-e1001987

2014

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Iron drives anabolic metabolism through active histone demethylation and mTORC1

Nature cell biology, 2023-10, Vol.25 (10), p.1478-1494

2023

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Folate-mediated intracellular drug delivery increases the anticancer efficacy of nanoparticulate formulation of arsenic trioxide

Molecular cancer therapeutics, 2009-07, Vol.8 (7), p.1955-1963

2009

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Transition Metal Speciation in the Cell: Insights from the Chemistry of Metal Ion Receptors

Science (American Association for the Advancement of Science), 2003-05, Vol.300 (5621), p.931-936

2003

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Complete Loss of Post-translational Modifications Triggers Fibrillar Aggregation of SOD1 in the Familial Form of Amyotrophic Lateral Sclerosis

The Journal of biological chemistry, 2008-08, Vol.283 (35), p.24167-24176

2008

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Zinc Sparks Are Triggered by Fertilization and Facilitate Cell Cycle Resumption in Mammalian Eggs

ACS chemical biology, 2011-07, Vol.6 (7), p.716-723

2011

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Interrogating Intracellular Zinc Chemistry with a Long Stokes Shift Zinc Probe ZincBY‑4

Journal of the American Chemical Society, 2019-10, Vol.141 (42), p.16696-16705

2019

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Anticancer Activity of Small-Molecule and Nanoparticulate Arsenic(III) Complexes

Inorganic chemistry, 2013-11, Vol.52 (21), p.12292-12304

2013

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Zur and zinc increase expression of E. coli ribosomal protein L31 through RNA-mediated repression of the repressor L31p

Nucleic acids research, 2022-12, Vol.50 (22), p.12739-12753

2022

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Femtomolar Sensitivity of Metalloregulatory Proteins Controlling Zinc Homeostasis

Science (American Association for the Advancement of Science), 2001-06, Vol.292 (5526), p.2488-2492

2001

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Christopher T. Walsh (1944-2023)

Dynamic zinc fluxes regulate meiotic progression in Caenorhabditis elegans

Arsenoplatin‑1 Is a Dual Pharmacophore Anticancer Agent

Allosteric transcriptional regulation via changes in the overall topology of the core promoter

CueR activates transcription through a DNA distortion mechanism

Quantitative mapping of zinc fluxes in the mammalian egg reveals the origin of fertilization-induced zinc sparks

Patient-Derived Tumor Xenografts Are Susceptible to Formation of Human Lymphocytic Tumors

Activation of superoxide dismutases: Putting the metal to the pedal

A place for thioether chemistry in cellular copper ion recognition and trafficking

Molecular Pathways: Revisiting Glycogen Synthase Kinase-3β as a Target for the Treatment of Cancer

A new role for Zinc limitation in bacterial pathogenicity: modulation of α-hemolysin from uropathogenic Escherichia coli

The bacterial multidrug resistance regulator BmrR distorts promoter DNA to activate transcription

The zinc spark is an inorganic signature of human egg activation

Quantitative imaging approaches to understanding biological processing of metal ions

Zinc availability regulates exit from meiosis in maturing mammalian oocytes

Structural and mechanistic basis of zinc regulation across the E. coli Zur regulon

Iron drives anabolic metabolism through active histone demethylation and mTORC1

Folate-mediated intracellular drug delivery increases the anticancer efficacy of nanoparticulate formulation of arsenic trioxide

Transition Metal Speciation in the Cell: Insights from the Chemistry of Metal Ion Receptors

Complete Loss of Post-translational Modifications Triggers Fibrillar Aggregation of SOD1 in the Familial Form of Amyotrophic Lateral Sclerosis

Zinc Sparks Are Triggered by Fertilization and Facilitate Cell Cycle Resumption in Mammalian Eggs

Interrogating Intracellular Zinc Chemistry with a Long Stokes Shift Zinc Probe ZincBY‑4

Anticancer Activity of Small-Molecule and Nanoparticulate Arsenic(III) Complexes

Zur and zinc increase expression of E. coli ribosomal protein L31 through RNA-mediated repression of the repressor L31p

Femtomolar Sensitivity of Metalloregulatory Proteins Controlling Zinc Homeostasis

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