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The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic

Biochemical Society transactions, 2015-08, Vol.43 (4), p.687-689

2015

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A translational synthetic biology platform for rapid access to gram-scale quantities of novel drug-like molecules

Metabolic engineering, 2017-07, Vol.42, p.185-193

2017

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Ferracyclic carbonyl complexes as anti-inflammatory agents

Chemical communications (Cambridge, England), 2020-04, Vol.56 (31), p.43-433

2020

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Cytotoxicity of Pyrazine-Based Cyclometalated (C^Npz^C)Au(III) Carbene Complexes: Impact of the Nature of the Ancillary Ligand on the Biological Properties

Inorganic chemistry, 2017-05, Vol.56 (10), p.5728-5740

2017

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Lipopolysaccharide-Induced Expression of NAD(P)H:Quinone Oxidoreductase 1 and Heme Oxygenase-1 Protects against Excessive Inflammatory Responses in Human Monocytes

The Journal of immunology (1950), 2008-11, Vol.181 (10), p.6730-6737

2008

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Common Phenolic Metabolites of Flavonoids, but Not Their Unmetabolized Precursors, Reduce the Secretion of Vascular Cellular Adhesion Molecules by Human Endothelial Cells

The Journal of nutrition, 2016-03, Vol.146 (3), p.465-473

2016

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Cardiovascular Mechanisms of Action of Anthocyanins May Be Associated with the Impact of Microbial Metabolites on Heme Oxygenase-1 in Vascular Smooth Muscle Cells

Molecules (Basel, Switzerland), 2018-04, Vol.23 (4), p.898

2018

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Signatures of anthocyanin metabolites identified in humans inhibit biomarkers of vascular inflammation in human endothelial cells

Molecular nutrition & food research, 2017-09, Vol.61 (9), p.1700053-n/a

2017

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Ruthenium carbamoyl complexes: Coordination chemistry and CO release

Inorganica Chimica Acta, 2021-05, Vol.520, p.120283, Article 120283

2021

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Anti-inflammatory Effect of a Cell-Penetrating Peptide Targeting the Nrf2/Keap1 Interaction

ACS medicinal chemistry letters, 2012-05, Vol.3 (5), p.407-410

2012

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Lipopolysaccharide-Induced Heme Oxygenase-1 Expression in Human Monocytic Cells Is Mediated via Nrf2 and Protein Kinase C

Journal of Immunology, 2005-10, Vol.175 (7), p.4408-4415

2005

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Formal Total Synthesis of (+)-C9-Deoxyomuralide from l‑Leucine Using a Double Sacrificial Chirality Transfer Approach

Journal of organic chemistry, 2017-12, Vol.82 (23), p.12209-12223

2017

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Solid-Phase Synthesis of Duocarmycin Analogues and the Effect of C‑Terminal Substitution on Biological Activity

Journal of organic chemistry, 2015-10, Vol.80 (19), p.9454-9467

2015

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Alpha-lipoic acid-induced heme oxygenase-1 expression is mediated by nuclear factor erythroid 2-related factor 2 and p38 mitogen-activated protein kinase in human monocytic cells

Arteriosclerosis, thrombosis, and vascular biology, 2005-10, Vol.25 (10), p.2100-2105

2005

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Role of protein kinase C δ in curcumin-induced antioxidant response element-mediated gene expression in human monocytes

Biochemical and biophysical research communications, 2006-03, Vol.341 (4), p.1007-1016

2006

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Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin

Bioorganic & medicinal chemistry letters, 2015-11, Vol.25 (21), p.4878-4880

2015

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Identification and characterisation of a G-quadruplex forming sequence in the promoter region of nuclear factor (erythroid-derived 2)-like 2 (Nrf2)

Biochemical and biophysical research communications, 2014-04, Vol.447 (1), p.128-132

2014

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Design and synthesis of threading intercalators to target DNA

Bioorganic & medicinal chemistry letters, 2010-12, Vol.20 (23), p.6956-6959

2010

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Perfluoroarene-based peptide macrocycles that inhibit the Nrf2/Keap1 interaction

Bioorganic & medicinal chemistry letters, 2018-09, Vol.28 (16), p.2728-2731

2018

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Synthesis and evaluation of 9-aminoacridines derived from benzyne click chemistry

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (20), p.5880-5883

2009

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A Gold(III) Pincer Ligand Scaffold for the Synthesis of Binuclear and Bioconjugated Complexes: Synthesis and Anticancer Potential

Chemistry : a European journal, 2018-03, Vol.24 (14), p.3613-3622

2018

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Borylation via iridium catalysed C-H activation: a new concise route to duocarmycin derivatives

Organic & biomolecular chemistry, 2024-07, Vol.22 (27), p.5603-5607

2024

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Vitamin D: Potential in the Prevention and Treatment of Lung Cancer

Anticancer research, 2012, Vol.32 (1), p.211-221

2012

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Flavonoid metabolites reduce tumor necrosis factor‐α secretion to a greater extent than their precursor compounds in human THP‐1 monocytes

Molecular nutrition & food research, 2015-06, Vol.59 (6), p.1143-1154

2015

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Flavonoid metabolites reduce tumor necrosis factor-[alpha] secretion to a greater extent than their precursor compounds in human THP-1 monocytes

Molecular nutrition & food research, 2015-06, Vol.59 (6), p.1143-1154

2015

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The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic

A translational synthetic biology platform for rapid access to gram-scale quantities of novel drug-like molecules

Ferracyclic carbonyl complexes as anti-inflammatory agents

Cytotoxicity of Pyrazine-Based Cyclometalated (C^Npz^C)Au(III) Carbene Complexes: Impact of the Nature of the Ancillary Ligand on the Biological Properties

Lipopolysaccharide-Induced Expression of NAD(P)H:Quinone Oxidoreductase 1 and Heme Oxygenase-1 Protects against Excessive Inflammatory Responses in Human Monocytes

Common Phenolic Metabolites of Flavonoids, but Not Their Unmetabolized Precursors, Reduce the Secretion of Vascular Cellular Adhesion Molecules by Human Endothelial Cells

Cardiovascular Mechanisms of Action of Anthocyanins May Be Associated with the Impact of Microbial Metabolites on Heme Oxygenase-1 in Vascular Smooth Muscle Cells

Signatures of anthocyanin metabolites identified in humans inhibit biomarkers of vascular inflammation in human endothelial cells

Ruthenium carbamoyl complexes: Coordination chemistry and CO release

Anti-inflammatory Effect of a Cell-Penetrating Peptide Targeting the Nrf2/Keap1 Interaction

Lipopolysaccharide-Induced Heme Oxygenase-1 Expression in Human Monocytic Cells Is Mediated via Nrf2 and Protein Kinase C

Formal Total Synthesis of (+)-C9-Deoxyomuralide from l‑Leucine Using a Double Sacrificial Chirality Transfer Approach

Solid-Phase Synthesis of Duocarmycin Analogues and the Effect of C‑Terminal Substitution on Biological Activity

Alpha-lipoic acid-induced heme oxygenase-1 expression is mediated by nuclear factor erythroid 2-related factor 2 and p38 mitogen-activated protein kinase in human monocytic cells

Role of protein kinase C δ in curcumin-induced antioxidant response element-mediated gene expression in human monocytes

Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin

Identification and characterisation of a G-quadruplex forming sequence in the promoter region of nuclear factor (erythroid-derived 2)-like 2 (Nrf2)

Design and synthesis of threading intercalators to target DNA

Perfluoroarene-based peptide macrocycles that inhibit the Nrf2/Keap1 interaction

Synthesis and evaluation of 9-aminoacridines derived from benzyne click chemistry

A Gold(III) Pincer Ligand Scaffold for the Synthesis of Binuclear and Bioconjugated Complexes: Synthesis and Anticancer Potential

Borylation via iridium catalysed C-H activation: a new concise route to duocarmycin derivatives

Vitamin D: Potential in the Prevention and Treatment of Lung Cancer

Flavonoid metabolites reduce tumor necrosis factor‐α secretion to a greater extent than their precursor compounds in human THP‐1 monocytes

Flavonoid metabolites reduce tumor necrosis factor-[alpha] secretion to a greater extent than their precursor compounds in human THP-1 monocytes

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