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Adverse outcome pathway networks I: Development and applications

Environmental toxicology and chemistry, 2018-06, Vol.37 (6), p.1723-1733

2018

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Transcriptomic points-of-departure from short-term exposure studies are protective of chronic effects for fish exposed to estrogenic chemicals

Toxicology and applied pharmacology, 2019-09, Vol.378, p.114634, Article 114634

2019

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Cross-Model Comparison of Transcriptomic Dose–Response of Short-Chain Chlorinated Paraffins

Environmental science & technology, 2021-06, Vol.55 (12), p.8149-8158

2021

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Adverse outcome pathway networks II: Network analytics

Environmental toxicology and chemistry, 2018-06, Vol.37 (6), p.1734-1748

2018

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In Vitro Screening of 21 Bisphenol A Replacement Alternatives: Compared with Bisphenol A, the Majority of Alternatives Are More Cytotoxic and Dysregulate More Genes in Avian Hepatocytes

Environmental toxicology and chemistry, 2021-07, Vol.40 (7), p.2026-2033

2021

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Toxicity Screening of Bisphenol A Replacement Compounds: Cytotoxicity and mRNA Expression in Primary Hepatocytes of Chicken and Double‐Crested Cormorant

Environmental toxicology and chemistry, 2021-05, Vol.40 (5), p.1368-1378

2021

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Contribution of emissions from the oil sands activities in Alberta, Canada to atmospheric concentration and deposition of nitrogen and sulfur species at a downwind site

Environmental pollution (1987), 2024-09, Vol.356, p.124301, Article 124301

2024

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Time-dependent transcriptomic and biochemical responses of 6-formylindolo[3,2-b]carbazole (FICZ) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) are explained by AHR activation time

Biochemical pharmacology, 2016-09, Vol.115, p.134-143

2016

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Empirical Characterization of False Discovery Rates of Differentially Expressed Genes and Transcriptomic Benchmark Concentrations in Zebrafish Embryos

Environmental science & technology, 2024-04, Vol.58 (14), p.6128-6137

2024

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Effects of two Bisphenol A replacement compounds, 1,7-bis (4-hydroxyphenylthio)-3,5-dioxaheptane and Bisphenol AF, on development and mRNA expression in chicken embryos

Ecotoxicology and environmental safety, 2021-06, Vol.215, p.112140, Article 112140

2021

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Evaluation of the Aryl Hydrocarbon Receptor Response in LMH 3D Spheroids

Environmental toxicology and chemistry, 2020-09, Vol.39 (9), p.1693-1701

2020

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Introducing AOP Reports: Collaborative review and publication of adverse outcome pathways

Environmental and molecular mutagenesis, 2022-03, Vol.63 (3), p.116-117

2022

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Integration of sperm DNA damage assessment into OECD test guidelines for genotoxicity testing using the MutaMouse model

Toxicology and applied pharmacology, 2018-10, Vol.357, p.10-18

2018

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Wildlife ecological risk assessment in the 21st century: Promising technologies to assess toxicological effects

Integrated environmental assessment and management, 2024-05, Vol.20 (3), p.725-748

2024

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Microsatellite mutation frequencies in river otters (Lontra Canadensis) from the Athabasca Oil Sands region are correlated to polycyclic aromatic compound tissue burden

Environmental and molecular mutagenesis, 2022-04, Vol.63 (4), p.172-183

2022

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Tris(1,3-dichloro-2-propyl) phosphate perturbs the expression of genes involved in immune response and lipid and steroid metabolism in chicken embryos

Toxicology and applied pharmacology, 2014-03, Vol.275 (2), p.104-112

2014

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Concentration‐ and time‐dependent induction of Cyp1a and DNA damage response by benzo(a)pyrene in LMH three‐dimensional spheroids

Environmental and molecular mutagenesis, 2021-06, Vol.62 (5), p.319-327

2021

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Prioritization of 10 organic flame retardants using an avian hepatocyte toxicogenomic assay

Environmental toxicology and chemistry, 2018-12, Vol.37 (12), p.3134-3144

2018

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Turkey Lakes Watershed, Ontario, Canada: 40 years of interdisciplinary whole‐ecosystem research

Hydrological processes, 2021-04, Vol.35 (4), p.n/a

2021

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ToxChip PCR Arrays for Two Arctic-Breeding Seabirds: Applications for Regional Environmental Assessments

Environmental science & technology, 2021-06, Vol.55 (11), p.7521-7530

2021

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Metabolomic profiles in relation to benchmark polycyclic aromatic compounds (PACs) and trace elements in two seabird species from Arctic Canada

Environmental research, 2022-03, Vol.204 (Pt B), p.112022-112022, Article 112022

2022

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A Case Study on Integrating a New Key Event Into an Existing Adverse Outcome Pathway on Oxidative DNA Damage: Challenges and Approaches in a Data-Rich Area

Frontiers in toxicology, 2022-04, Vol.4, p.827328-827328

2022

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A Pragmatic Approach to Adverse Outcome Pathway Development and Evaluation

Toxicological sciences, 2021-11, Vol.184 (2), p.183-190

2021

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Folate deficiency increases chromosomal damage and mutations in hematopoietic cells in the transgenic mutamouse model

Environmental and molecular mutagenesis, 2018-06, Vol.59 (5), p.366-374

2018

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Toxicity screening of bisphenol A replacement compounds: cytotoxicity and mRNA expression in LMH 3D spheroids

Environmental science and pollution research international, 2022-06, Vol.29 (29), p.44769-44778

2022

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Adverse outcome pathway networks I: Development and applications

Transcriptomic points-of-departure from short-term exposure studies are protective of chronic effects for fish exposed to estrogenic chemicals

Cross-Model Comparison of Transcriptomic Dose–Response of Short-Chain Chlorinated Paraffins

Adverse outcome pathway networks II: Network analytics

In Vitro Screening of 21 Bisphenol A Replacement Alternatives: Compared with Bisphenol A, the Majority of Alternatives Are More Cytotoxic and Dysregulate More Genes in Avian Hepatocytes

Toxicity Screening of Bisphenol A Replacement Compounds: Cytotoxicity and mRNA Expression in Primary Hepatocytes of Chicken and Double‐Crested Cormorant

Contribution of emissions from the oil sands activities in Alberta, Canada to atmospheric concentration and deposition of nitrogen and sulfur species at a downwind site

Time-dependent transcriptomic and biochemical responses of 6-formylindolo[3,2-b]carbazole (FICZ) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) are explained by AHR activation time

Empirical Characterization of False Discovery Rates of Differentially Expressed Genes and Transcriptomic Benchmark Concentrations in Zebrafish Embryos

Effects of two Bisphenol A replacement compounds, 1,7-bis (4-hydroxyphenylthio)-3,5-dioxaheptane and Bisphenol AF, on development and mRNA expression in chicken embryos

Evaluation of the Aryl Hydrocarbon Receptor Response in LMH 3D Spheroids

Introducing AOP Reports: Collaborative review and publication of adverse outcome pathways

Integration of sperm DNA damage assessment into OECD test guidelines for genotoxicity testing using the MutaMouse model

Wildlife ecological risk assessment in the 21st century: Promising technologies to assess toxicological effects

Microsatellite mutation frequencies in river otters (Lontra Canadensis) from the Athabasca Oil Sands region are correlated to polycyclic aromatic compound tissue burden

Tris(1,3-dichloro-2-propyl) phosphate perturbs the expression of genes involved in immune response and lipid and steroid metabolism in chicken embryos

Concentration‐ and time‐dependent induction of Cyp1a and DNA damage response by benzo(a)pyrene in LMH three‐dimensional spheroids

Prioritization of 10 organic flame retardants using an avian hepatocyte toxicogenomic assay

Turkey Lakes Watershed, Ontario, Canada: 40 years of interdisciplinary whole‐ecosystem research

ToxChip PCR Arrays for Two Arctic-Breeding Seabirds: Applications for Regional Environmental Assessments

Metabolomic profiles in relation to benchmark polycyclic aromatic compounds (PACs) and trace elements in two seabird species from Arctic Canada

A Case Study on Integrating a New Key Event Into an Existing Adverse Outcome Pathway on Oxidative DNA Damage: Challenges and Approaches in a Data-Rich Area

A Pragmatic Approach to Adverse Outcome Pathway Development and Evaluation

Folate deficiency increases chromosomal damage and mutations in hematopoietic cells in the transgenic mutamouse model

Toxicity screening of bisphenol A replacement compounds: cytotoxicity and mRNA expression in LMH 3D spheroids

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