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Synthesis and Biochemical Evaluation of 3‑Phenoxy-1,4-diarylazetidin-2-ones as Tubulin-Targeting Antitumor Agents

Journal of medicinal chemistry, 2016-01, Vol.59 (1), p.90-113

2016

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Lead Optimization of Benzoxepin-Type Selective Estrogen Receptor (ER) Modulators and Downregulators with Subtype-Specific ERα and ERβ Activity

Journal of medicinal chemistry, 2018-01, Vol.61 (2), p.514-534

2018

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Synthesis and Evaluation of Azetidinone Analogues of Combretastatin A-4 as Tubulin Targeting Agents

Journal of medicinal chemistry, 2010-12, Vol.53 (24), p.8569-8584

2010

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β‑Lactam Estrogen Receptor Antagonists and a Dual-Targeting Estrogen Receptor/Tubulin Ligand

Journal of medicinal chemistry, 2014-11, Vol.57 (22), p.9370-9382

2014

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Colchicine-Binding Site Inhibitors from Chemistry to Clinic: A Review

Pharmaceuticals (Basel, Switzerland), 2020-01, Vol.13 (1), p.8

2020

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Skin lipids in health and disease: A review

Chemistry and physics of lipids, 2021-05, Vol.236, p.105055-105055, Article 105055

2021

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Potent Quinoline-Containing Combretastatin A-4 Analogues: Design, Synthesis, Antiproliferative, and Anti-Tubulin Activity

Pharmaceuticals (Basel, Switzerland), 2020-11, Vol.13 (11), p.393

2020

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Topical Application of Metal Allergens Induces Changes to Lipid Composition of Human Skin

Frontiers in toxicology, 2022, Vol.4, p.867163-867163

2022

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Application of 2D EXSY and qNMR Spectroscopy for Diastereomeric Excess Determination Following Chiral Resolution of β‐Lactams

ChemistryOpen (Weinheim), 2023-06, Vol.12 (6), p.e202200119-n/a

2023

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Chirality of New Drug Approvals (2013–2022): Trends and Perspectives

Journal of medicinal chemistry, 2024-02, Vol.67 (4), p.2305-2320

2024

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Bioactivation of cinnamic alcohol in a reconstructed human epidermis model and evaluation of sensitizing potency of the identified metabolites

Frontiers in toxicology, 2024-07, Vol.6, p.1398852

2024

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Synthesis and Biological Evaluation of 1-(Diarylmethyl)-1H-1,2,4-triazoles and 1-(Diarylmethyl)-1H-imidazoles as a Novel Class of Anti-Mitotic Agent for Activity in Breast Cancer

Pharmaceuticals (Basel, Switzerland), 2021-02, Vol.14 (2), p.169

2021

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Candidaantarctica Lipase B mediated kinetic resolution: A sustainable method for chiral synthesis of antiproliferative β-lactams

European journal of medicinal chemistry, 2024-10, Vol.276, p.116692, Article 116692

2024

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Epoxy Resin Monomers with Reduced Skin Sensitizing Potency

Chemical research in toxicology, 2014-06, Vol.27 (6), p.1002-1010

2014

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Combretazet-3 a novel synthetic cis-stable combretastatin A-4- azetidinone hybrid with enhanced stability and therapeutic efficacy in colon cancer

Oncology reports, 2013-06, Vol.29 (6), p.2451-2458

2013

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Novel cis-restricted β-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro

Oncology reports, 2013-02, Vol.29 (2), p.585-594

2013

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Special Issue “Anticancer Drugs”

Pharmaceuticals (Basel, Switzerland), 2019-09, Vol.12 (3), p.134

2019

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Synthesis and Pro-Apoptotic Effects of Nitrovinylanthracenes and Related Compounds in Chronic Lymphocytic Leukaemia (CLL) and Burkitt's Lymphoma (BL)

Molecules (Basel, Switzerland), 2023-12, Vol.28 (24), p.8095

2023

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Antiproliferative and Tubulin-Destabilising Effects of 3-(Prop-1-en-2-yl)azetidin-2-Ones and Related Compounds in MCF-7 and MDA-MB-231 Breast Cancer Cells

Pharmaceuticals (Basel, Switzerland), 2023-07, Vol.16 (7), p.1000

2023

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Synthesis, Characterisation and Mechanism of Action of Anticancer 3-Fluoroazetidin-2-ones

Pharmaceuticals (Basel, Switzerland), 2022-08, Vol.15 (9), p.1044

2022

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Nature-derived epoxy resins: Synthesis, allergenicity, and thermosetting properties of pinoresinol diglycidyl ether

Toxicology and industrial health, 2022-05, Vol.38 (5), p.259-269

2022

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Piperlongumine (piplartine) and analogues: Antiproliferative microtubule-destabilising agents

European journal of medicinal chemistry, 2017-01, Vol.125, p.453-463

2017

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Synthesis and Biochemical Evaluation of Ethanoanthracenes and Related Compounds: Antiproliferative and Pro-Apoptotic Effects in Chronic Lymphocytic Leukemia (CLL)

Pharmaceuticals (Basel, Switzerland), 2024-08, Vol.17 (8), p.1034

2024

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A lipidomic approach towards identifying the effects of fragrance hydroperoxides on keratinocytes

Contact dermatitis, 2024-10

2024

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β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells

European journal of medicinal chemistry, 2020-03, Vol.189, p.112050-112050, Article 112050

2020

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Synthesis and Biochemical Evaluation of 3‑Phenoxy-1,4-diarylazetidin-2-ones as Tubulin-Targeting Antitumor Agents

Lead Optimization of Benzoxepin-Type Selective Estrogen Receptor (ER) Modulators and Downregulators with Subtype-Specific ERα and ERβ Activity

Synthesis and Evaluation of Azetidinone Analogues of Combretastatin A-4 as Tubulin Targeting Agents

β‑Lactam Estrogen Receptor Antagonists and a Dual-Targeting Estrogen Receptor/Tubulin Ligand

Colchicine-Binding Site Inhibitors from Chemistry to Clinic: A Review

Skin lipids in health and disease: A review

Potent Quinoline-Containing Combretastatin A-4 Analogues: Design, Synthesis, Antiproliferative, and Anti-Tubulin Activity

Topical Application of Metal Allergens Induces Changes to Lipid Composition of Human Skin

Application of 2D EXSY and qNMR Spectroscopy for Diastereomeric Excess Determination Following Chiral Resolution of β‐Lactams

Chirality of New Drug Approvals (2013–2022): Trends and Perspectives

Bioactivation of cinnamic alcohol in a reconstructed human epidermis model and evaluation of sensitizing potency of the identified metabolites

Synthesis and Biological Evaluation of 1-(Diarylmethyl)-1H-1,2,4-triazoles and 1-(Diarylmethyl)-1H-imidazoles as a Novel Class of Anti-Mitotic Agent for Activity in Breast Cancer

Candidaantarctica Lipase B mediated kinetic resolution: A sustainable method for chiral synthesis of antiproliferative β-lactams

Epoxy Resin Monomers with Reduced Skin Sensitizing Potency

Combretazet-3 a novel synthetic cis-stable combretastatin A-4- azetidinone hybrid with enhanced stability and therapeutic efficacy in colon cancer

Novel cis-restricted β-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro

Special Issue “Anticancer Drugs”

Synthesis and Pro-Apoptotic Effects of Nitrovinylanthracenes and Related Compounds in Chronic Lymphocytic Leukaemia (CLL) and Burkitt's Lymphoma (BL)

Antiproliferative and Tubulin-Destabilising Effects of 3-(Prop-1-en-2-yl)azetidin-2-Ones and Related Compounds in MCF-7 and MDA-MB-231 Breast Cancer Cells

Synthesis, Characterisation and Mechanism of Action of Anticancer 3-Fluoroazetidin-2-ones

Nature-derived epoxy resins: Synthesis, allergenicity, and thermosetting properties of pinoresinol diglycidyl ether

Piperlongumine (piplartine) and analogues: Antiproliferative microtubule-destabilising agents

Synthesis and Biochemical Evaluation of Ethanoanthracenes and Related Compounds: Antiproliferative and Pro-Apoptotic Effects in Chronic Lymphocytic Leukemia (CLL)

A lipidomic approach towards identifying the effects of fragrance hydroperoxides on keratinocytes

β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells

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