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Diverse, Potent, and Efficacious Inhibitors That Target the EED Subunit of the Polycomb Repressive Complex 2 Methyltransferase

Journal of medicinal chemistry, 2021-12, Vol.64 (23), p.17146-17183

2021

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The Next Generation of Pattern Recognition Receptor Agonists: Improving Response Rates in Cancer Immunotherapy

Current medicinal chemistry, 2020-01, Vol.27 (34), p.5654

2020

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Peptides as a platform for targeted therapeutics for cancer: peptide-drug conjugates (PDCs)

Chemical Society reviews, 2021-02, Vol.5 (3), p.148-1494

2021

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Trends in Molecular Properties, Bioavailability, and Permeability across the Bayer Compound Collection

Journal of medicinal chemistry, 2023-02, Vol.66 (4), p.2347-2360

2023

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Targeting PRC2 for the treatment of cancer: an updated patent review (2016 - 2020)

Expert opinion on therapeutic patents, 2021-02, Vol.31 (2), p.119-135

2021

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C−H Activation Enables a Concise Total Synthesis of Quinine and Analogues with Enhanced Antimalarial Activity

Angewandte Chemie (International ed.), 2018-08, Vol.57 (33), p.10737-10741

International ed. in English, 2018

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EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex

Cell chemical biology, 2020-01, Vol.27 (1), p.41-46.e17

2020

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Discovery and characterisation of quinazolines and 8-Azaquinazolines as NLRP3 agonists with oral bioavailability in mice

Bioorganic & medicinal chemistry letters, 2023-11, Vol.96, p.129518-129518, Article 129518

2023

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Efficient development of stable and highly functionalised peptides targeting the CK2α/CK2β protein-protein interaction

Chemical science (Cambridge), 2019-05, Vol.1 (19), p.556-563

2019

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Free energy perturbation in the design of EED ligands as inhibitors of polycomb repressive complex 2 (PRC2) methyltransferase

Bioorganic & medicinal chemistry letters, 2021-05, Vol.39, p.127904-127904, Article 127904

2021

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Stapled peptides as a new technology to investigate protein-protein interactions in human platelets

Chemical science (Cambridge), 2018-05, Vol.9 (20), p.4638-4643

2018

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Trends in Molecular Properties, Bioavailability, and Permeability across the Bayer Compound Collection: Miniperspective

Journal of medicinal chemistry, 2023-02, Vol.66 (4), p.2347-2360

2023

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Substitution effects on neutral and protonated pyridine derivatives along the periodic table

Structural chemistry, 2008-04, Vol.19 (2), p.339-352

2008

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The reductive cleavage of picolinic amides

Tetrahedron letters, 2016-07, Vol.57 (27-28), p.2962-2964

2016

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Efficient development of stable and highly functionalised peptides targeting the CK2α/CK2β protein–protein interaction† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc00798a

Chemical science (Cambridge), 2019-04, Vol.10 (19), p.5056-5063

2019

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C‐H‐Aktivierung ermöglicht eine kurze Totalsynthese von Chinin und Analoga mit erhöhter Anti‐Malaria‐Aktivität

Angewandte Chemie, 2018-08, Vol.130 (33), p.10897-10901

2018

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Targeted Protein Degradation – The Story So Far

Inducing Targeted Protein Degradation, 2022

Cromm, Philipp

2022

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Stapled peptides as a new technology to investigate protein-protein interactions in human plateletsElectronic supplementary information (ESI) available. See DOI: 10.1039/c8sc00284c

2018-05

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Stapled peptides as a new technology to investigate protein–protein interactions in human platelets† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc00284c

Chemical science (Cambridge), 2018-04, Vol.9 (20), p.4638-4643

2018

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ChemInform Abstract: The Reductive Cleavage of Picolinic Amides

ChemInform, 2016-10, Vol.47 (43), p.no-no

2016

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C‐H‐Aktivierung ermöglicht eine kurze Totalsynthese von Chinin und Analoga mit erhöhter Anti‐Malaria‐Aktivität

Angewandte Chemie, 2018-08, Vol.130 (33), p.10897-10901

2018

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A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

Nature genetics, 2011-09, Vol.43 (11), p.1098-1103

2011

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Bird tolerance to humans in open tropical ecosystems

Nature communications, 2023-04, Vol.14 (1), p.2146-2146, Article 2146

2023

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Comparative Treatment Outcomes for Patients With Idiopathic Subglottic Stenosis

JAMA otolaryngology-- head & neck surgery, 2020-01, Vol.146 (1), p.20

2020

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Resilience to Large, “Catastrophic” Wildfires in North America's Grassland Biome

Earth's future, 2020-07, Vol.8 (7), p.n/a

2020

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Diverse, Potent, and Efficacious Inhibitors That Target the EED Subunit of the Polycomb Repressive Complex 2 Methyltransferase

The Next Generation of Pattern Recognition Receptor Agonists: Improving Response Rates in Cancer Immunotherapy

Peptides as a platform for targeted therapeutics for cancer: peptide-drug conjugates (PDCs)

Trends in Molecular Properties, Bioavailability, and Permeability across the Bayer Compound Collection

Targeting PRC2 for the treatment of cancer: an updated patent review (2016 - 2020)

C−H Activation Enables a Concise Total Synthesis of Quinine and Analogues with Enhanced Antimalarial Activity

EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex

Discovery and characterisation of quinazolines and 8-Azaquinazolines as NLRP3 agonists with oral bioavailability in mice

Efficient development of stable and highly functionalised peptides targeting the CK2α/CK2β protein-protein interaction

Free energy perturbation in the design of EED ligands as inhibitors of polycomb repressive complex 2 (PRC2) methyltransferase

Stapled peptides as a new technology to investigate protein-protein interactions in human platelets

Trends in Molecular Properties, Bioavailability, and Permeability across the Bayer Compound Collection: Miniperspective

Substitution effects on neutral and protonated pyridine derivatives along the periodic table

The reductive cleavage of picolinic amides

Efficient development of stable and highly functionalised peptides targeting the CK2α/CK2β protein–protein interaction† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc00798a

C‐H‐Aktivierung ermöglicht eine kurze Totalsynthese von Chinin und Analoga mit erhöhter Anti‐Malaria‐Aktivität

Targeted Protein Degradation – The Story So Far

Stapled peptides as a new technology to investigate protein-protein interactions in human plateletsElectronic supplementary information (ESI) available. See DOI: 10.1039/c8sc00284c

Stapled peptides as a new technology to investigate protein–protein interactions in human platelets† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc00284c

ChemInform Abstract: The Reductive Cleavage of Picolinic Amides

C‐H‐Aktivierung ermöglicht eine kurze Totalsynthese von Chinin und Analoga mit erhöhter Anti‐Malaria‐Aktivität

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

Bird tolerance to humans in open tropical ecosystems

Comparative Treatment Outcomes for Patients With Idiopathic Subglottic Stenosis

Resilience to Large, “Catastrophic” Wildfires in North America's Grassland Biome

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