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Eosinophils and eosinophil-associated diseases: An update

Journal of allergy and clinical immunology, 2018-02, Vol.141 (2), p.505-517

2018

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Eosinophil and mast cell Siglecs: From biology to drug target

Journal of leukocyte biology, 2020-07, Vol.108 (1), p.73-81

2020

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Memory Precursors and Short-Lived Effector T cell Subsets Have Different Sensitivities to TGFβ

International journal of molecular sciences, 2023-02, Vol.24 (4), p.3930

2023

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Leveraging Siglec-8 endocytic mechanisms to kill human eosinophils and malignant mast cells

Journal of allergy and clinical immunology, 2018-05, Vol.141 (5), p.1774-1785.e7

2018

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Siglecs in allergy and asthma

Molecular aspects of medicine, 2023-04, Vol.90, p.101104-101104, Article 101104

2023

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Siglecs as potential targets of therapy in human mast cell- and/or eosinophil-associated diseases

Seminars in immunology, 2023-09, Vol.69, p.101799-101799, Article 101799

2023

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Siglec-8 Signals Through a Non-Canonical Pathway to Cause Human Eosinophil Death In Vitro

Frontiers in immunology, 2021-10, Vol.12, p.737988-737988

2021

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Interactions between Siglec-8 and endogenous sialylated cis ligands restrain cell death induction in human eosinophils and mast cells

Frontiers in immunology, 2023-10, Vol.14, p.1283370-1283370

2023

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NKG2D signaling shifts the balance of CD8 T cells from single cytokine- to polycytokine-producing effector cells

Molecular immunology, 2023-03, Vol.155, p.1-6

2023

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Frontline Science: Characterization of a novel mouse strain expressing human Siglec‐8 only on eosinophils

Journal of leukocyte biology, 2018-07, Vol.104 (1), p.11-19

2018

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Drug delivery targets and strategies to address mast cell diseases

Expert opinion on drug delivery, 2023-02, Vol.20 (2), p.205-222

2023

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Single-site, five-year experience with human eosinophil isolation by density gradient centrifugation and CD16 immunomagnetic negative separation

BMC research notes, 2020-04, Vol.13 (1), p.211-211, Article 211

2020

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Identification of a Siglec‐F+ granulocyte‐macrophage progenitor

Journal of leukocyte biology, 2018-07, Vol.104 (1), p.123-133

2018

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Glycobiology of Eosinophilic Inflammation: Contributions of Siglecs, Glycans, and Other Glycan-Binding Proteins

Frontiers in medicine, 2017-08, Vol.4, p.116-116

2017

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NKG2D signaling on CD8⁺ T cells represses T-bet and rescues CD4-unhelped CD8⁺ T cell memory recall but not effector responses

Nature medicine, 2012-03, Vol.18 (3), p.422-428

2012

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Stimulation of the glucocorticoid-induced TNF receptor family-related receptor on CD8 T cells induces protective and high-avidity T cell responses to tumor-specific antigens

The Journal of immunology (1950), 2011-01, Vol.186 (1), p.275-283

2011

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Sialic acid–binding immunoglobulin-like lectin 8 (Siglec-8) is an activating receptor mediating β2-integrin–dependent function in human eosinophils

Journal of allergy and clinical immunology, 2018-06, Vol.141 (6), p.2196-2207

2018

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Development of tumor-infiltrating CD8+ T cell memory precursor effector cells and antimelanoma memory responses are the result of vaccination and TGF-β blockade during the perioperative period of tumor resection

The Journal of immunology (1950), 2011-03, Vol.186 (6), p.3309-3316

2011

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CD8(+) T cells sabotage their own memory potential through IFN-γ-dependent modification of the IL-12/IL-15 receptor α axis on dendritic cells

The Journal of immunology (1950), 2012-04, Vol.188 (8), p.3639-3647

2012

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Discovery, Function, and Therapeutic Targeting of Siglec-8

Cells (Basel, Switzerland), 2020-12, Vol.10 (1), p.19

2020

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CD8 Co-receptor promotes susceptibility of CD8⁺ T cells to transforming growth factor-β (TGF-β)-mediated suppression

Cancer Immunology, Immunotherapy, 2011-02, Vol.60 (2), p.291-297

2011

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Siglec-8 Engagement Selectively Inhibits Allergen-Dependent Degranulation of Human Skin Mast Cells In Vitro

Journal of allergy and clinical immunology, 2019-02, Vol.143 (2), p.AB179-AB179

2019

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Priming with very low-affinity peptide ligands gives rise to CD8+ T-cell effectors with enhanced function but with greater susceptibility to transforming growth factor (TGF)β-mediated suppression

Cancer Immunology, Immunotherapy, 2011-11, Vol.60 (11), p.1543-1551

2011

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Functional and Phenotypic Characterization of Siglec-6 on Human Mast Cells

Cells (Basel, Switzerland), 2022-03, Vol.11 (7), p.1138

2022

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Engagement of NK receptor NKG2D, but not 2B4, results in self-reactive CD8+T cells and autoimmune vitiligo

Autoimmunity (Chur, Switzerland), 2011-12, Vol.44 (8), p.599-606

2011

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Eosinophils and eosinophil-associated diseases: An update

Eosinophil and mast cell Siglecs: From biology to drug target

Memory Precursors and Short-Lived Effector T cell Subsets Have Different Sensitivities to TGFβ

Leveraging Siglec-8 endocytic mechanisms to kill human eosinophils and malignant mast cells

Siglecs in allergy and asthma

Siglecs as potential targets of therapy in human mast cell- and/or eosinophil-associated diseases

Siglec-8 Signals Through a Non-Canonical Pathway to Cause Human Eosinophil Death In Vitro

Interactions between Siglec-8 and endogenous sialylated cis ligands restrain cell death induction in human eosinophils and mast cells

NKG2D signaling shifts the balance of CD8 T cells from single cytokine- to polycytokine-producing effector cells

Frontline Science: Characterization of a novel mouse strain expressing human Siglec‐8 only on eosinophils

Drug delivery targets and strategies to address mast cell diseases

Single-site, five-year experience with human eosinophil isolation by density gradient centrifugation and CD16 immunomagnetic negative separation

Identification of a Siglec‐F+ granulocyte‐macrophage progenitor

Glycobiology of Eosinophilic Inflammation: Contributions of Siglecs, Glycans, and Other Glycan-Binding Proteins

NKG2D signaling on CD8⁺ T cells represses T-bet and rescues CD4-unhelped CD8⁺ T cell memory recall but not effector responses

Stimulation of the glucocorticoid-induced TNF receptor family-related receptor on CD8 T cells induces protective and high-avidity T cell responses to tumor-specific antigens

Sialic acid–binding immunoglobulin-like lectin 8 (Siglec-8) is an activating receptor mediating β2-integrin–dependent function in human eosinophils

Development of tumor-infiltrating CD8+ T cell memory precursor effector cells and antimelanoma memory responses are the result of vaccination and TGF-β blockade during the perioperative period of tumor resection

CD8(+) T cells sabotage their own memory potential through IFN-γ-dependent modification of the IL-12/IL-15 receptor α axis on dendritic cells

Discovery, Function, and Therapeutic Targeting of Siglec-8

CD8 Co-receptor promotes susceptibility of CD8⁺ T cells to transforming growth factor-β (TGF-β)-mediated suppression

Siglec-8 Engagement Selectively Inhibits Allergen-Dependent Degranulation of Human Skin Mast Cells In Vitro

Priming with very low-affinity peptide ligands gives rise to CD8+ T-cell effectors with enhanced function but with greater susceptibility to transforming growth factor (TGF)β-mediated suppression

Functional and Phenotypic Characterization of Siglec-6 on Human Mast Cells

Engagement of NK receptor NKG2D, but not 2B4, results in self-reactive CD8+T cells and autoimmune vitiligo

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