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Reductive Cross-Coupling of Nonaromatic, Heterocyclic Bromides with Aryl and Heteroaryl Bromides

Journal of organic chemistry, 2014-06, Vol.79 (12), p.5771-5780

2014

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Insulin Regulation of Proteostasis and Clinical Implications

Cell metabolism, 2017-08, Vol.26 (2), p.310-323

2017

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Diet‐induced obesity causes insulin resistance in mouse brown adipose tissue

Obesity (Silver Spring, Md.), 2015-09, Vol.23 (9), p.1765-1770

2015

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Engaging Nonaromatic, Heterocyclic Tosylates in Reductive Cross-Coupling with Aryl and Heteroaryl Bromides

Journal of organic chemistry, 2015-03, Vol.80 (5), p.2907-2911

2015

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Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function

Diabetes (New York, N.Y.), 2016-08, Vol.65 (8), p.2201-2213

2016

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Differential Role of Insulin/IGF-1 Receptor Signaling in Muscle Growth and Glucose Homeostasis

Cell reports (Cambridge), 2015-05, Vol.11 (8), p.1220-1235

2015

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Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair Myocardial energetics in obesity

Circulation (New York, N.Y.), 2005-10, Vol.112 (17), p.2686-2695

2005

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Differential roles of FOXO transcription factors on insulin action in brown and white adipose tissue

The Journal of clinical investigation, 2021-10, Vol.131 (19), p.1-16

2021

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Ketoreductase/Transaminase, One-Pot, Multikilogram Biocatalytic Cascade Reaction

Organic process research & development, 2021-04, Vol.25 (4), p.941-946

2021

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Contribution of Impaired Myocardial Insulin Signaling to Mitochondrial Dysfunction and Oxidative Stress in the Heart

Circulation (New York, N.Y.), 2009-03, Vol.119 (9), p.1272-1283

2009

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Role of PKCδ in Insulin Sensitivity and Skeletal Muscle Metabolism

Diabetes (New York, N.Y.), 2015-12, Vol.64 (12), p.4023-4032

2015

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Elamipretide treatment during pregnancy ameliorates the progression of polycystic kidney disease in maternal and neonatal mice with PKD1 mutations

Kidney international, 2022-05, Vol.101 (5), p.906-911

2022

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Functional resilience of C57BL/6J mouse heart to dietary fat overload

American journal of physiology. Heart and circulatory physiology, 2021-11, Vol.321 (5), p.H850-H864

2021

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Immediate preoperative hyperglycemia correlates with complications in non-cardiac surgical cases

Journal of clinical anesthesia, 2021-11, Vol.74, p.110375-110375, Article 110375

2021

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Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

The Journal of clinical investigation, 2018-03, Vol.128 (3), p.1199-1199

2018

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Spiropiperidine Sultam and Lactam Templates: Diastereoselective Overman Rearrangement and Metathesis followed by NH Arylation

Journal of organic chemistry, 2017-12, Vol.82 (23), p.12246-12256

2017

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Enhanced Cardiac Akt/Protein Kinase B Signaling Contributes to Pathological Cardiac Hypertrophy in Part by Impairing Mitochondrial Function via Transcriptional Repression of Mitochondrion-Targeted Nuclear Genes

Molecular and cellular biology, 2015-03, Vol.35 (5), p.831-846

2015

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Loss of FoxOs in muscle increases strength and mitochondrial function during aging

Journal of cachexia, sarcopenia and muscle, 2023-02, Vol.14 (1), p.243-259

2023

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Cardiac PI3K-Akt Impairs Insulin-Stimulated Glucose Uptake Independent of mTORC1 and GLUT4 Translocation

Molecular endocrinology (Baltimore, Md.), 2013-01, Vol.27 (1), p.172-184

2013

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Akt1 in the cardiovascular system: friend or foe?

The Journal of clinical investigation, 2005-08, Vol.115 (8), p.2059-2064

2005

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Stereoselective Synthesis of Spiropiperidines as BACE‑1 Aspartyl Protease Inhibitors via Late Stage N‑Arylation of a 1,8-Diazaspiro[4.5]dec-3-en-2-one Pharmacophore

Journal of organic chemistry, 2013-03, Vol.78 (6), p.2661-2669

2013

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Loss of FoxOs in muscle reveals sex-based differences in insulin sensitivity but mitigates diet-induced obesity

Molecular metabolism (Germany), 2019-12, Vol.30, p.203-220

2019

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FoxO Transcription Factors Are Critical Regulators of Diabetes-Related Muscle Atrophy

Diabetes (New York, N.Y.), 2019-03, Vol.68 (3), p.556-570

2019

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α4β2 nicotinic acetylcholine receptor partial agonists with low intrinsic efficacy have antidepressant-like properties

Behavioural pharmacology, 2011-08, Vol.22 (4), p.291

2011

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242-LB: A Novel FoxO Target, LRRC2, Preserves Mitochondrial Function in Muscle from Insulin-Deficient Mice

Diabetes (New York, N.Y.), 2023-06, Vol.72 (Supplement_1), p.1

2023

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Reductive Cross-Coupling of Nonaromatic, Heterocyclic Bromides with Aryl and Heteroaryl Bromides

Insulin Regulation of Proteostasis and Clinical Implications

Diet‐induced obesity causes insulin resistance in mouse brown adipose tissue

Engaging Nonaromatic, Heterocyclic Tosylates in Reductive Cross-Coupling with Aryl and Heteroaryl Bromides

Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function

Differential Role of Insulin/IGF-1 Receptor Signaling in Muscle Growth and Glucose Homeostasis

Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair Myocardial energetics in obesity

Differential roles of FOXO transcription factors on insulin action in brown and white adipose tissue

Ketoreductase/Transaminase, One-Pot, Multikilogram Biocatalytic Cascade Reaction

Contribution of Impaired Myocardial Insulin Signaling to Mitochondrial Dysfunction and Oxidative Stress in the Heart

Role of PKCδ in Insulin Sensitivity and Skeletal Muscle Metabolism

Elamipretide treatment during pregnancy ameliorates the progression of polycystic kidney disease in maternal and neonatal mice with PKD1 mutations

Functional resilience of C57BL/6J mouse heart to dietary fat overload

Immediate preoperative hyperglycemia correlates with complications in non-cardiac surgical cases

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

Spiropiperidine Sultam and Lactam Templates: Diastereoselective Overman Rearrangement and Metathesis followed by NH Arylation

Enhanced Cardiac Akt/Protein Kinase B Signaling Contributes to Pathological Cardiac Hypertrophy in Part by Impairing Mitochondrial Function via Transcriptional Repression of Mitochondrion-Targeted Nuclear Genes

Loss of FoxOs in muscle increases strength and mitochondrial function during aging

Cardiac PI3K-Akt Impairs Insulin-Stimulated Glucose Uptake Independent of mTORC1 and GLUT4 Translocation

Akt1 in the cardiovascular system: friend or foe?

Stereoselective Synthesis of Spiropiperidines as BACE‑1 Aspartyl Protease Inhibitors via Late Stage N‑Arylation of a 1,8-Diazaspiro[4.5]dec-3-en-2-one Pharmacophore

Loss of FoxOs in muscle reveals sex-based differences in insulin sensitivity but mitigates diet-induced obesity

FoxO Transcription Factors Are Critical Regulators of Diabetes-Related Muscle Atrophy

α4β2 nicotinic acetylcholine receptor partial agonists with low intrinsic efficacy have antidepressant-like properties

242-LB: A Novel FoxO Target, LRRC2, Preserves Mitochondrial Function in Muscle from Insulin-Deficient Mice

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