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Small molecules enhance autophagy and reduce toxicity in Huntington's disease models

Nature chemical biology, 2007-05, Vol.3 (6), p.331-338

2007

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Lysosomal positioning coordinates cellular nutrient responses

Nature cell biology, 2011-04, Vol.13 (4), p.453-460

2011

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Complex Inhibitory Effects of Nitric Oxide on Autophagy

Molecular cell, 2011-07, Vol.43 (1), p.19-32

2011

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Axonal Endoplasmic Reticulum Dynamics and Its Roles in Neurodegeneration

Frontiers in neuroscience, 2020-01, Vol.14, p.48-48

2020

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PICALM modulates autophagy activity and tau accumulation

Nature communications, 2014-09, Vol.5 (1), p.4998-4998, Article 4998

2014

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CCT complex restricts neuropathogenic protein aggregation via autophagy

Nature communications, 2016-12, Vol.7 (1), p.13821-13821, Article 13821

2016

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α-Synuclein impairs macroautophagy: implications for Parkinson's disease

The Journal of cell biology, 2010-09, Vol.190 (6), p.1023-1037

2010

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Modeling of axonal endoplasmic reticulum network by spastic paraplegia proteins

eLife, 2017-07, Vol.6

2017

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Small molecules enhance autophagy and reduce toxicity in Huntington's disease models

Nature chemical biology, 2007-06, Vol.3 (6), p.331-338

2007

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Active zone scaffolds differentially accumulate Unc13 isoforms to tune Ca2+ channel–vesicle coupling

Nature neuroscience, 2016-10, Vol.19 (10), p.1311-1320

2016

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A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin

Human molecular genetics, 2008-01, Vol.17 (2), p.170-178

2008

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Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

Nature chemical biology, 2008-05, Vol.4 (5), p.295-305

2008

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Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

Nature chemical biology, 2008-03, Vol.4 (5), p.295-305

2008

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How neurons maintain their axons long-term: an integrated view of axon biology and pathology

Frontiers in neuroscience, 2023-07, Vol.17, p.1236815

2023

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Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease

Journal of cell science, 2008-05, Vol.121 (Pt 10), p.1649-1660

2008

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Drosophila SPG12 ortholog, reticulon-like 1, governs presynaptic ER organization and Ca2+ dynamics

The Journal of cell biology, 2023-06, Vol.222 (6), p.1

2023

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GAL4 Drivers Specific for Type Ib and Type Is Motor Neurons in Drosophila

G3 : genes - genomes - genetics, 2019-02, Vol.9 (2), p.453-462

2019

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Nature genetics, 2004-06, Vol.36 (6), p.585-595

2004

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Rapamycin pre-treatment protects against apoptosis

Human molecular genetics, 2006-04, Vol.15 (7), p.1209-1216

2006

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Rapamycin alleviates toxicity of different aggregate-prone proteins

Human molecular genetics, 2006-02, Vol.15 (3), p.433-442

2006

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Mushroom body output neurons MBON-a1/a2 define an odor intensity channel that regulates behavioral odor discrimination learning in larval Drosophila

Frontiers in physiology, 2023-05, Vol.14, p.1111244-1111244

2023

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Editorial: Hereditary Spastic Paraplegias: At the Crossroads of Molecular Pathways and Clinical Options

Frontiers in neuroscience, 2021-06, Vol.15, p.708642-708642

2021

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Multiple Spectral Inputs Improve Motion Discrimination in the Drosophila Visual System

Science (American Association for the Advancement of Science), 2012-05, Vol.336 (6083), p.925-931

2012

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Virtual Fly Brain-An interactive atlas of the Drosophila nervous system

Frontiers in physiology, 2023-01, Vol.14, p.1076533

2023

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Dynein mutations impair autophagic clearance of aggregate-prone proteins

Nature genetics, 2005-07, Vol.37 (7), p.771-776

2005

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Small molecules enhance autophagy and reduce toxicity in Huntington's disease models

Lysosomal positioning coordinates cellular nutrient responses

Complex Inhibitory Effects of Nitric Oxide on Autophagy

Axonal Endoplasmic Reticulum Dynamics and Its Roles in Neurodegeneration

PICALM modulates autophagy activity and tau accumulation

CCT complex restricts neuropathogenic protein aggregation via autophagy

α-Synuclein impairs macroautophagy: implications for Parkinson's disease

Modeling of axonal endoplasmic reticulum network by spastic paraplegia proteins

Small molecules enhance autophagy and reduce toxicity in Huntington's disease models

Active zone scaffolds differentially accumulate Unc13 isoforms to tune Ca2+ channel–vesicle coupling

A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

How neurons maintain their axons long-term: an integrated view of axon biology and pathology

Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease

Drosophila SPG12 ortholog, reticulon-like 1, governs presynaptic ER organization and Ca2+ dynamics

GAL4 Drivers Specific for Type Ib and Type Is Motor Neurons in Drosophila

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Rapamycin pre-treatment protects against apoptosis

Rapamycin alleviates toxicity of different aggregate-prone proteins

Mushroom body output neurons MBON-a1/a2 define an odor intensity channel that regulates behavioral odor discrimination learning in larval Drosophila

Editorial: Hereditary Spastic Paraplegias: At the Crossroads of Molecular Pathways and Clinical Options

Multiple Spectral Inputs Improve Motion Discrimination in the Drosophila Visual System

Virtual Fly Brain-An interactive atlas of the Drosophila nervous system

Dynein mutations impair autophagic clearance of aggregate-prone proteins

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