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Therapeutic Potential of IL-15 and N-803 in HIV/SIV Infection

Viruses, 2021-09, Vol.13 (9), p.1750

2021

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Mathematical modeling indicates that regulatory inhibition of CD8+ T cell cytotoxicity can limit efficacy of IL-15 immunotherapy in cases of high pre-treatment SIV viral load

PLoS computational biology, 2023-08, Vol.19 (8), p.e1011425-e1011425

2023

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MAIT cells are functionally impaired in a Mauritian cynomolgus macaque model of SIV and Mtb co-infection

PLoS pathogens, 2020-05, Vol.16 (5), p.e1008585-e1008585

2020

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The mucosal barrier and anti-viral immune responses can eliminate portions of the viral population during transmission and early viral growth

PloS one, 2021-12, Vol.16 (12), p.e0260010-e0260010

2021

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Mathematical modeling of N-803 treatment in SIV-infected non-human primates

PLoS computational biology, 2021-07, Vol.17 (7), p.e1009204-e1009204

2021

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Characterization of the SARS-CoV-2 B.1.621 (Mu) variant

Science translational medicine, 2022-08, Vol.14 (657), p.eabm4908

2022

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Zika Virus Infection of Pregnant Ifnar1 -/- Mice Triggers Strain-Specific Differences in Fetal Outcomes

Journal of virology, 2021-10, Vol.95 (21), p.e0081821-e0081821

2021

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Using barcoded Zika virus to assess virus population structure in vitro and in Aedes aegypti mosquitoes

Virology (New York, N.Y.), 2018-08, Vol.521, p.138-148

2018

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Translating viral vaccines into immunity

Science (American Association for the Advancement of Science), 2021-01, Vol.371 (6528), p.460-461

2021

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A new genotype of hepatitis A virus causing transient liver enzyme elevations in Mauritius-origin laboratory-housed Macaca fascicularis

Veterinary pathology, 2024-05, Vol.61 (3), p.488-496

2024

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Control of Simian Immunodeficiency Virus Infection in Prophylactically Vaccinated, Antiretroviral Treatment-Naive Macaques Is Required for the Most Efficacious CD8 T Cell Response during Treatment with the Interleukin-15 Superagonist N-803

Journal of virology, 2022-10, Vol.96 (20), p.e0118522

2022

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IL-15 Superagonist N-803 Enhances IFN-γ Production of MAIT Cells in SIV + Macaques

Infection and immunity, 2022-10, Vol.90 (10), p.e0025922

2022

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Pre-existing Simian Immunodeficiency Virus Infection Increases Expression of T Cell Markers Associated with Activation during Early Mycobacterium tuberculosis Coinfection and Impairs TNF Responses in Granulomas

The Journal of immunology (1950), 2021-07, Vol.207 (1), p.175-188

2021

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Host Immunity to Mycobacterium tuberculosis Infection Is Similar in Simian Immunodeficiency Virus (SIV)-Infected, Antiretroviral Therapy-Treated and SIV-Naïve Juvenile Macaques

Infection and immunity, 2023-05, Vol.91 (5), p.e0055822-e0055822

2023

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Bone marrow stromal cells from multiple myeloma patients uniquely induce bortezomib resistant NF-κB activity in myeloma cells

Molecular cancer, 2010-07, Vol.9 (1), p.176-176, Article 176

2010

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Monkeying around with MAIT Cells: Studying the Role of MAIT Cells in SIV and Mtb Co-Infection

Viruses, 2021-05, Vol.13 (5), p.863

2021

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Prior infection with SARS-CoV-2 WA1/2020 partially protects rhesus macaques against reinfection with B.1.1.7 and B.1.351 variants

Science translational medicine, 2021-11, Vol.13 (618), p.eabj2641

2021

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Preexisting Simian Immunodeficiency Virus Infection Increases Susceptibility to Tuberculosis in Mauritian Cynomolgus Macaques

Infection and immunity, 2018-12, Vol.86 (12)

2018

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Quantitation of Productively Infected Monocytes and Macrophages of Simian Immunodeficiency Virus-Infected Macaques

Journal of virology, 2016-06, Vol.90 (12), p.5643-5656

2016

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Transient T Cell Expansion, Activation, and Proliferation in Therapeutically Vaccinated Simian Immunodeficiency Virus-Positive Macaques Treated with N-803

Journal of virology, 2022-12, Vol.96 (23), p.e0142422

2022

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Gain without pain: adaptation and increased virulence of Zika virus in vertebrate host without fitness cost in mosquito vector

Journal of virology, 2023-10, Vol.97 (10), p.e0116223-e0116223

2023

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Characterization of major histocompatibility complex-related molecule 1 sequence variants in non-human primates

Immunogenetics (New York), 2019-02, Vol.71 (2), p.109-121

2019

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ALT-803 Transiently Reduces Simian Immunodeficiency Virus Replication in the Absence of Antiretroviral Treatment

Journal of virology, 2018-02, Vol.92 (3)

2018

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Validation of multiplex PCR sequencing assay of SIV

Virology journal, 2021-01, Vol.18 (1), p.21-21, Article 21

2021

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Four Methods for Monitoring SARS-CoV-2 and Influenza A Virus Activity in Schools

JAMA network open, 2023-12, Vol.6 (12), p.e2346329

2023

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Therapeutic Potential of IL-15 and N-803 in HIV/SIV Infection

Mathematical modeling indicates that regulatory inhibition of CD8+ T cell cytotoxicity can limit efficacy of IL-15 immunotherapy in cases of high pre-treatment SIV viral load

MAIT cells are functionally impaired in a Mauritian cynomolgus macaque model of SIV and Mtb co-infection

The mucosal barrier and anti-viral immune responses can eliminate portions of the viral population during transmission and early viral growth

Mathematical modeling of N-803 treatment in SIV-infected non-human primates

Characterization of the SARS-CoV-2 B.1.621 (Mu) variant

Zika Virus Infection of Pregnant Ifnar1 -/- Mice Triggers Strain-Specific Differences in Fetal Outcomes

Using barcoded Zika virus to assess virus population structure in vitro and in Aedes aegypti mosquitoes

Translating viral vaccines into immunity

A new genotype of hepatitis A virus causing transient liver enzyme elevations in Mauritius-origin laboratory-housed Macaca fascicularis

Control of Simian Immunodeficiency Virus Infection in Prophylactically Vaccinated, Antiretroviral Treatment-Naive Macaques Is Required for the Most Efficacious CD8 T Cell Response during Treatment with the Interleukin-15 Superagonist N-803

IL-15 Superagonist N-803 Enhances IFN-γ Production of MAIT Cells in SIV + Macaques

Pre-existing Simian Immunodeficiency Virus Infection Increases Expression of T Cell Markers Associated with Activation during Early Mycobacterium tuberculosis Coinfection and Impairs TNF Responses in Granulomas

Host Immunity to Mycobacterium tuberculosis Infection Is Similar in Simian Immunodeficiency Virus (SIV)-Infected, Antiretroviral Therapy-Treated and SIV-Naïve Juvenile Macaques

Bone marrow stromal cells from multiple myeloma patients uniquely induce bortezomib resistant NF-κB activity in myeloma cells

Monkeying around with MAIT Cells: Studying the Role of MAIT Cells in SIV and Mtb Co-Infection

Prior infection with SARS-CoV-2 WA1/2020 partially protects rhesus macaques against reinfection with B.1.1.7 and B.1.351 variants

Preexisting Simian Immunodeficiency Virus Infection Increases Susceptibility to Tuberculosis in Mauritian Cynomolgus Macaques

Quantitation of Productively Infected Monocytes and Macrophages of Simian Immunodeficiency Virus-Infected Macaques

Transient T Cell Expansion, Activation, and Proliferation in Therapeutically Vaccinated Simian Immunodeficiency Virus-Positive Macaques Treated with N-803

Gain without pain: adaptation and increased virulence of Zika virus in vertebrate host without fitness cost in mosquito vector

Characterization of major histocompatibility complex-related molecule 1 sequence variants in non-human primates

ALT-803 Transiently Reduces Simian Immunodeficiency Virus Replication in the Absence of Antiretroviral Treatment

Validation of multiplex PCR sequencing assay of SIV

Four Methods for Monitoring SARS-CoV-2 and Influenza A Virus Activity in Schools

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