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Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47-mediated 'don't-eat-me' signal

Nature immunology, 2019-03, Vol.20 (3), p.265

2019

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CAR T cell immunotherapy for human cancer

Science (American Association for the Advancement of Science), 2018-03, Vol.359 (6382), p.1361-1365

2018

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CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy

Nature communications, 2021-02, Vol.12 (1), p.877-877, Article 877

2021

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Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis

The Journal of clinical investigation, 2015-06, Vol.125 (6), p.2293-2306

2015

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Current Status and Challenges of Vaccination Therapy for Glioblastoma

Molecular cancer therapeutics, 2023-04, Vol.22 (4), p.435-446

2023

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Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

Immunity (Cambridge, Mass.), 2016-02, Vol.44 (2), p.380-390

2016

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The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations

Scientific reports, 2018-04, Vol.8 (1), p.6289-9, Article 6289

2018

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Imaging CAR T Cell Trafficking with eDHFR as a PET Reporter Gene

Molecular therapy, 2020-01, Vol.28 (1), p.42-51

2020

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In Like a Lamb; Out Like a Lion: Marching CAR T Cells Toward Enhanced Efficacy in B-ALL

Molecular cancer therapeutics, 2021-07, Vol.20 (7), p.1223-1233

2021

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Substrate rigidity regulates human T cell activation and proliferation

The Journal of immunology (1950), 2012-08, Vol.189 (3), p.1330-1339

2012

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Rapid manufacturing of non-activated potent CAR T cells

Nature biomedical engineering, 2022-02, Vol.6 (2), p.118

2022

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Itacitinib (INCB039110), a JAK1 Inhibitor, Reduces Cytokines Associated with Cytokine Release Syndrome Induced by CAR T-cell Therapy

Clinical cancer research, 2020-12, Vol.26 (23), p.6299-6309

2020

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Improving T Cell Expansion with a Soft Touch

Nano letters, 2017-02, Vol.17 (2), p.821-826

2017

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Checkmate: Metabolic flexibility with a STING in its tail

Science advances, 2023-12, Vol.9 (49), p.eadm6816-eadm6816

O'Connor, Roddy S

2023

Volltextzugriff (PDF)

Testing the Specificity of Compounds Designed to Inhibit CPT1A in T Cells

Methods in molecular biology (Clifton, N.J.), 2020, Vol.2097, p.83

2020

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Reducing Ex Vivo Culture Improves the Antileukemic Activity of Chimeric Antigen Receptor (CAR) T Cells

Cancer immunology research, 2018-09, Vol.6 (9), p.1100-1109

2018

Volltextzugriff (PDF)

Enhancing chimeric antigen receptor T cell therapy by modulating the p53 signaling network with Δ133p53α

Proceedings of the National Academy of Sciences - PNAS, 2024-03, Vol.121 (10), p.e2317735121

2024

Volltextzugriff (PDF)

Lingering effects of chemotherapy on mature T cells impair proliferation

Blood advances, 2020-10, Vol.4 (19), p.4653-4664

2020

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High-Throughput Mechanobiology Screening Platform Using Micro- and Nanotopography

Nano letters, 2016-04, Vol.16 (4), p.2198-2204

2016

Volltextzugriff (PDF)

Nicotinamide enhances natural killer cell function and yields remissions in patients with non-Hodgkin lymphoma

Science translational medicine, 2023-07, Vol.15 (705), p.eade3341

2023

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Recent Metabolic Advances for Preventing and Treating Acute and Chronic Graft Versus Host Disease

Frontiers in immunology, 2021-10, Vol.12, p.757836-757836

2021

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Exploiting the CD200-CD200R immune checkpoint axis in multiple myeloma to enhance CAR T-cell therapy

Blood, 2024-01, Vol.143 (2), p.139

2024

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Quantification of lactoyl-CoA (lactyl-CoA) by liquid chromatography mass spectrometry in mammalian cells and tissues

Open biology, 2020-09, Vol.10 (9), p.200187-200187

2020

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Enhancing Chimeric Antigen Receptor T Cell Anti-tumor Function through Advanced Media Design

Molecular therapy. Methods & clinical development, 2020-09, Vol.18, p.595-606

2020

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Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47-mediated 'don't-eat-me' signal

CAR T cell immunotherapy for human cancer

CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy

Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis

Current Status and Challenges of Vaccination Therapy for Glioblastoma

Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations

Imaging CAR T Cell Trafficking with eDHFR as a PET Reporter Gene

In Like a Lamb; Out Like a Lion: Marching CAR T Cells Toward Enhanced Efficacy in B-ALL

Substrate rigidity regulates human T cell activation and proliferation

Rapid manufacturing of non-activated potent CAR T cells

Itacitinib (INCB039110), a JAK1 Inhibitor, Reduces Cytokines Associated with Cytokine Release Syndrome Induced by CAR T-cell Therapy

Improving T Cell Expansion with a Soft Touch

Checkmate: Metabolic flexibility with a STING in its tail

Testing the Specificity of Compounds Designed to Inhibit CPT1A in T Cells

Reducing Ex Vivo Culture Improves the Antileukemic Activity of Chimeric Antigen Receptor (CAR) T Cells

Enhancing chimeric antigen receptor T cell therapy by modulating the p53 signaling network with Δ133p53α

Lingering effects of chemotherapy on mature T cells impair proliferation

High-Throughput Mechanobiology Screening Platform Using Micro- and Nanotopography

Nicotinamide enhances natural killer cell function and yields remissions in patients with non-Hodgkin lymphoma

Recent Metabolic Advances for Preventing and Treating Acute and Chronic Graft Versus Host Disease

Exploiting the CD200-CD200R immune checkpoint axis in multiple myeloma to enhance CAR T-cell therapy

Quantification of lactoyl-CoA (lactyl-CoA) by liquid chromatography mass spectrometry in mammalian cells and tissues

Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality

Enhancing Chimeric Antigen Receptor T Cell Anti-tumor Function through Advanced Media Design

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