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Alkali supplementation as a therapeutic in chronic kidney disease: what mediates protection?

American journal of physiology. Renal physiology, 2020-12, Vol.319 (6), p.F1090-F1104

2020

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New mechanisms for the kidney-protective effect of alkali in chronic kidney disease

Clinical science (1979), 2022-10, Vol.136 (20), p.1433-1437

2022

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Reactive oxygen species as important determinants of medullary flow, sodium excretion, and hypertension

American journal of physiology. Renal physiology, 2015-02, Vol.308 (3), p.F179-F197

2015

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Greater high-mobility group box 1 in male compared with female spontaneously hypertensive rats worsens renal ischemia-reperfusion injury

Clinical science (1979), 2020-07, Vol.134 (13), p.1751-1762

2020

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NaHCO3 loading causes increased arterial pressure and kidney damage in rats with chronic kidney disease

Clinical science (1979), 2024-02, Vol.138 (4), p.189-203

2024

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Identification of novel macropinocytosis inhibitors using a rational screen of Food and Drug Administration‐approved drugs

British journal of pharmacology, 2018-09, Vol.175 (18), p.3640-3655

2018

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Haemodynamic influences on kidney oxygenation: Clinical implications of integrative physiology

Clinical and experimental pharmacology & physiology, 2013-02, Vol.40 (2), p.106-122

2013

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Differential release of extracellular vesicle tRNA from oxidative stressed renal cells and ischemic kidneys

Scientific reports, 2022-01, Vol.12 (1), p.1646-1646, Article 1646

2022

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Intrarenal oxygenation: unique challenges and the biophysical basis of homeostasis

American journal of physiology. Renal physiology, 2008-11, Vol.295 (5), p.F1259-F1270

2008

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Developmental Exposure to Endocrine Disruptors Expands Murine Myometrial Stem Cell Compartment as a Prerequisite to Leiomyoma Tumorigenesis

Stem cells (Dayton, Ohio), 2017-03, Vol.35 (3), p.666-678

2017

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Necrosis Contributes to the Development of Hypertension in Male, but Not Female, Spontaneously Hypertensive Rats

Hypertension (Dallas, Tex. 1979), 2019-12, Vol.74 (6), p.1524-1531

2019

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IL-18 (Interleukin-18) Produced by Renal Tubular Epithelial Cells Promotes Renal Inflammation and Injury During Deoxycorticosterone/Salt-Induced Hypertension in Mice

Hypertension (Dallas, Tex. 1979), 2021-11, Vol.78 (5), p.1296-1309

2021

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RENAL OXYGEN DELIVERY: MATCHING DELIVERY TO METABOLIC DEMAND

Clinical and experimental pharmacology & physiology, 2006-10, Vol.33 (10), p.961-967

O'Connor, Paul M

2006

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Vasa recta pericyte density is negatively associated with vascular congestion in the renal medulla following ischemia reperfusion in rats

American journal of physiology. Renal physiology, 2017-11, Vol.313 (5), p.F1097-F1105

2017

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Persistent vascular congestion in male spontaneously hypertensive rats contributes to delayed recovery of renal function following renal ischemia perfusion compared with females

Clinical science (1979), 2022-06, Vol.136 (11), p.825-840

2022

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NAD(P)H oxidase and renal epithelial ion transport

American journal of physiology. Regulatory, integrative and comparative physiology, 2011-05, Vol.300 (5), p.R1023-R1029

2011

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Oral NaHCO3 Activates a Splenic Anti-Inflammatory Pathway: Evidence That Cholinergic Signals Are Transmitted via Mesothelial Cells

The Journal of immunology (1950), 2018-05, Vol.200 (10), p.3568-3586

2018

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Renal mass reduction increases the response to exogenous insulin independent of acid-base status or plasma insulin levels in rats

American journal of physiology. Renal physiology, 2021-10, Vol.321 (4), p.F494-F504

2021

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A basic solution to activate the cholinergic anti-inflammatory pathway via the mesothelium?

Pharmacological research, 2019-03, Vol.141, p.236-248

2019

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Lipopolysaccharide Pretreatment Prevents Medullary Vascular Congestion following Renal Ischemia by Limiting Early Reperfusion of the Medullary Circulation

Journal of the American Society of Nephrology, 2022-04, Vol.33 (4), p.769-785

2022

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Ultrasound measurement of change in kidney volume is a sensitive indicator of severity of renal parenchymal injury

American journal of physiology. Renal physiology, 2020-09, Vol.319 (3), p.F447-F457

2020

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Initiation and Progression of Chronic Kidney Disease: Can We Definitively Test the Chronic Hypoxia Hypothesis?

Hypertension (Dallas, Tex. 1979), 2013-11, Vol.62 (5), p.827-828

2013

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Brown-Norway chromosome 1 mitigates the upregulation of proinflammatory pathways in mTAL cells and subsequent age-related CKD in Dahl SS/JrHsdMcwi rats

American journal of physiology. Renal physiology, 2023-02, Vol.324 (2), p.F193-F210

2023

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Deficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension

Journal of the American Society of Nephrology, 2013-07, Vol.24 (7), p.1053-1062

2013

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High-salt diet blunts renal autoregulation by a reactive oxygen species-dependent mechanism

American journal of physiology. Renal physiology, 2014-07, Vol.307 (1), p.F33-F40

2014

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Alkali supplementation as a therapeutic in chronic kidney disease: what mediates protection?

New mechanisms for the kidney-protective effect of alkali in chronic kidney disease

Reactive oxygen species as important determinants of medullary flow, sodium excretion, and hypertension

Greater high-mobility group box 1 in male compared with female spontaneously hypertensive rats worsens renal ischemia-reperfusion injury

NaHCO3 loading causes increased arterial pressure and kidney damage in rats with chronic kidney disease

Identification of novel macropinocytosis inhibitors using a rational screen of Food and Drug Administration‐approved drugs

Haemodynamic influences on kidney oxygenation: Clinical implications of integrative physiology

Differential release of extracellular vesicle tRNA from oxidative stressed renal cells and ischemic kidneys

Intrarenal oxygenation: unique challenges and the biophysical basis of homeostasis

Developmental Exposure to Endocrine Disruptors Expands Murine Myometrial Stem Cell Compartment as a Prerequisite to Leiomyoma Tumorigenesis

Necrosis Contributes to the Development of Hypertension in Male, but Not Female, Spontaneously Hypertensive Rats

IL-18 (Interleukin-18) Produced by Renal Tubular Epithelial Cells Promotes Renal Inflammation and Injury During Deoxycorticosterone/Salt-Induced Hypertension in Mice

RENAL OXYGEN DELIVERY: MATCHING DELIVERY TO METABOLIC DEMAND

Vasa recta pericyte density is negatively associated with vascular congestion in the renal medulla following ischemia reperfusion in rats

Persistent vascular congestion in male spontaneously hypertensive rats contributes to delayed recovery of renal function following renal ischemia perfusion compared with females

NAD(P)H oxidase and renal epithelial ion transport

Oral NaHCO3 Activates a Splenic Anti-Inflammatory Pathway: Evidence That Cholinergic Signals Are Transmitted via Mesothelial Cells

Renal mass reduction increases the response to exogenous insulin independent of acid-base status or plasma insulin levels in rats

A basic solution to activate the cholinergic anti-inflammatory pathway via the mesothelium?

Lipopolysaccharide Pretreatment Prevents Medullary Vascular Congestion following Renal Ischemia by Limiting Early Reperfusion of the Medullary Circulation

Ultrasound measurement of change in kidney volume is a sensitive indicator of severity of renal parenchymal injury

Initiation and Progression of Chronic Kidney Disease: Can We Definitively Test the Chronic Hypoxia Hypothesis?

Brown-Norway chromosome 1 mitigates the upregulation of proinflammatory pathways in mTAL cells and subsequent age-related CKD in Dahl SS/JrHsdMcwi rats

Deficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension

High-salt diet blunts renal autoregulation by a reactive oxygen species-dependent mechanism

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