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Impact of a baseline polymorphism on the emergence of resistance to the hepatitis C virus nonstructural protein 5a replication complex inhibitor, BMS-790052

Hepatology (Baltimore, Md.), 2012-06, Vol.55 (6), p.1692-1699

2012

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Hepatitis C Virus RNA Elimination and Development of Resistance in Replicon Cells Treated with BMS-790052

Antimicrobial Agents and Chemotherapy, 2012-03, Vol.56 (3), p.1350-1358

2012

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Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect

Nature (London), 2010-05, Vol.465 (7294), p.96-100

2010

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Characterizations of HCV NS5A replication complex inhibitors

Virology (New York, N.Y.), 2013-09, Vol.444 (1), p.343-354

2013

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Persistence of Resistant Variants in Hepatitis C Virus-Infected Patients Treated with the NS5A Replication Complex Inhibitor Daclatasvir

Antimicrobial Agents and Chemotherapy, 2013-05, Vol.57 (5), p.2054-2065

2013

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Specific Inhibition of Bovine Viral Diarrhea Virus Replicase

Journal of Virology, 2003-06, Vol.77 (12), p.6753-6760

2003

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Resensitizing daclatasvir-resistant hepatitis C variants by allosteric modulation of NS5A

Nature (London), 2015-11, Vol.527 (7577), p.245-248

2015

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In Vitro Activity of BMS-790052 on Hepatitis C Virus Genotype 4 NS5A

Antimicrobial Agents and Chemotherapy, 2012-03, Vol.56 (3), p.1588-1590

2012

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Discovery of Potent Hepatitis C Virus NS5A Inhibitors with Dimeric Structures

Antimicrobial Agents and Chemotherapy, 2011-08, Vol.55 (8), p.3795-3802

2011

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Development of a Cell-Based High-Throughput Specificity Screen Using a Hepatitis C Virus-Bovine Viral Diarrhea Virus Dual Replicon Assay

Antimicrobial Agents and Chemotherapy, 2005-04, Vol.49 (4), p.1346-1353

2005

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effects of NS5A inhibitors on NS5A phosphorylation, polyprotein processing and localization

Journal of general virology, 2011-11, Vol.92 (Pt 11), p.2502-2511

2011

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HCV NS5A replication complex inhibitors. Part 3: discovery of potent analogs with distinct core topologies

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (3), p.779-784

2013

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A 96-well based analysis of replicon elimination with the HCV NS5A replication complex inhibitor daclatasvir

Journal of virological methods, 2013-10, Vol.193 (1), p.68-76

2013

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Replication-Competent Chimeric Hepatitis C Virus Subgenomic Replicons

Intervirology, 2005-01, Vol.48 (2-3), p.183-191

2005

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The Effect of Internal Autocleavage on Kinetic Properties of the Human Cytomegalovirus Protease Catalytic Domain (∗)

The Journal of biological chemistry, 1995-03, Vol.270 (9), p.4753-4758

1995

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Stimulation of the Herpes Simplex Virus Type I Protease by Antichaeotrophic Salts (∗)

The Journal of biological chemistry, 1995-12, Vol.270 (50), p.30168-30172

1995

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Identification of Hepatitis C Virus NS5A Inhibitors

Journal of Virology, 2010-01, Vol.84 (1), p.482-491

2010

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HCV NS5A replication complex inhibitors. Part 2: Investigation of stilbene prolinamides

Bioorganic & medicinal chemistry letters, 2012-10, Vol.22 (19), p.6063-6066

2012

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Identification of the serine residue at the active site of the herpes simplex virus type 1 protease

The Journal of biological chemistry, 1994-04, Vol.269 (17), p.12672-12676

1994

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Deletion of the VP16 open reading frame of herpes simplex virus type 1

Journal of Virology, 1992-01, Vol.66 (1), p.258-269

1992

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Autoproteolysis of herpes simplex virus type 1 protease releases an active catalytic domain found in intermediate capsid particles

Journal of Virology, 1993-10, Vol.67 (10), p.5813-5822

1993

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Identification of a Novel Peptide Substrate of HSV-1 Protease Using Substrate Phage Display

Virology (New York, N.Y.), 1997-09, Vol.236 (2), p.338-347

1997

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Investigation of the specificity of the herpes simplex virus type 1 protease by point mutagenesis of the autoproteolysis sites

Journal of Virology, 1994-01, Vol.68 (1), p.526-529

1994

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Functional Conservations of the Alkaline Nuclease of Herpes Simplex Type 1 and Human Cytomegalovirus

Virology (New York, N.Y.), 1998-09, Vol.249 (2), p.460-470

1998

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Restriction endonuclease patterns of cytomegalovirus after passage in humans

The Journal of infectious diseases, 1987-02, Vol.155 (2), p.317-319

1987

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Impact of a baseline polymorphism on the emergence of resistance to the hepatitis C virus nonstructural protein 5a replication complex inhibitor, BMS-790052

Hepatitis C Virus RNA Elimination and Development of Resistance in Replicon Cells Treated with BMS-790052

Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect

Characterizations of HCV NS5A replication complex inhibitors

Persistence of Resistant Variants in Hepatitis C Virus-Infected Patients Treated with the NS5A Replication Complex Inhibitor Daclatasvir

Specific Inhibition of Bovine Viral Diarrhea Virus Replicase

Resensitizing daclatasvir-resistant hepatitis C variants by allosteric modulation of NS5A

In Vitro Activity of BMS-790052 on Hepatitis C Virus Genotype 4 NS5A

Discovery of Potent Hepatitis C Virus NS5A Inhibitors with Dimeric Structures

Development of a Cell-Based High-Throughput Specificity Screen Using a Hepatitis C Virus-Bovine Viral Diarrhea Virus Dual Replicon Assay

effects of NS5A inhibitors on NS5A phosphorylation, polyprotein processing and localization

HCV NS5A replication complex inhibitors. Part 3: discovery of potent analogs with distinct core topologies

A 96-well based analysis of replicon elimination with the HCV NS5A replication complex inhibitor daclatasvir

Replication-Competent Chimeric Hepatitis C Virus Subgenomic Replicons

The Effect of Internal Autocleavage on Kinetic Properties of the Human Cytomegalovirus Protease Catalytic Domain (∗)

Stimulation of the Herpes Simplex Virus Type I Protease by Antichaeotrophic Salts (∗)

Identification of Hepatitis C Virus NS5A Inhibitors

HCV NS5A replication complex inhibitors. Part 2: Investigation of stilbene prolinamides

Identification of the serine residue at the active site of the herpes simplex virus type 1 protease

Deletion of the VP16 open reading frame of herpes simplex virus type 1

Autoproteolysis of herpes simplex virus type 1 protease releases an active catalytic domain found in intermediate capsid particles

Identification of a Novel Peptide Substrate of HSV-1 Protease Using Substrate Phage Display

Investigation of the specificity of the herpes simplex virus type 1 protease by point mutagenesis of the autoproteolysis sites

Functional Conservations of the Alkaline Nuclease of Herpes Simplex Type 1 and Human Cytomegalovirus

Restriction endonuclease patterns of cytomegalovirus after passage in humans

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