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Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis

Proceedings of the National Academy of Sciences - PNAS, 2017-05, Vol.114 (22), p.E4462-E4471

2017

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Topiramate for Migraine Prevention in Adolescents: A Pooled Analysis of Efficacy and Safety

Headache, 2006-11, Vol.46 (10), p.1503-1510

2006

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Long-Term Open-Label Study of Adjunctive Topiramate in Infants With Refractory Partial-Onset Seizures

Journal of child neurology, 2011-10, Vol.26 (10), p.1271-1283

2011

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Adaptive Behavior Outcomes in Infants Treated With Adjunctive Topiramate

Pediatric neurology, 2012-06, Vol.46 (6), p.350-358

2012

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Radial Glial Identity Is Promoted by Notch1 Signaling in the Murine Forebrain

Neuron (Cambridge, Mass.), 2000-05, Vol.26 (2), p.395-404

2000

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Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells

Genes & development, 2002-04, Vol.16 (7), p.846-858

2002

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Intracellular Retention of Caveolin 1 in Presenilin-deficient Cells

The Journal of biological chemistry, 2005-02, Vol.280 (8), p.6663-6668

2005

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Alzheimer's disease research and development: a call for a new research roadmap

Annals of the New York Academy of Sciences, 2014-04, Vol.1313 (1), p.1-16

2014

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Effects of galantamine in a 2-year, randomized, placebo-controlled study in Alzheimer's disease

Neuropsychiatric disease and treatment, 2014-01, Vol.10, p.391-401

2014

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Identification and Characterization of Presenilin-independent Notch Signaling

The Journal of biological chemistry, 2002-03, Vol.277 (10), p.8154-8165

2002

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Effect of concomitant use of memantine on mortality and efficacy outcomes of galantamine-treated patients with Alzheimer's disease: post-hoc analysis of a randomized placebo-controlled study

Alzheimer's research & therapy, 2016-11, Vol.8 (1), p.47-47, Article 47

2016

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Pharmacokinetic–pharmacodynamic assessment of topiramate dosing regimens for children with epilepsy 2 to <10 years of age

Epilepsia (Copenhagen), 2010-10, Vol.51 (10), p.1954-1962

2010

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Changes in gamma-secretase activity and specificity caused by the introduction of consensus aspartyl protease active motif in Presenilin 1

Molecular neurodegeneration, 2008-05, Vol.3 (1), p.6-6, Article 6

2008

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Modeling complex neuropsychiatric disorders with human induced pluripotent stem cells

Current opinion in pharmacology, 2011-10, Vol.11 (5), p.521-527

2011

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Evaluation of JNJ-26489112 in patients with photosensitive epilepsy: A placebo-controlled, exploratory study

Epilepsy research, 2014-05, Vol.108 (4), p.709-716

2014

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Spatiotemporal selectivity of response to Notch1 signals in mammalian forebrain precursors

Development (Cambridge), 2001-03, Vol.128 (5), p.689-702

2001

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The effect of galantamine on brain atrophy rate in subjects with mild cognitive impairment is modified by apolipoprotein E genotype: post-hoc analysis of data from a randomized controlled trial

Alzheimer's research & therapy, 2014-07, Vol.6 (4), p.47-47

2014

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Signal Transduction by Activated mNotch: Importance of Proteolytic Processing and its Regulation by the Extracellular Domain

Proceedings of the National Academy of Sciences - PNAS, 1996-02, Vol.93 (4), p.1683-1688

1996

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The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD

Development (Cambridge), 1994-09, Vol.120 (9), p.2385-2396

1994

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Implications and limitations of cellular reprogramming for psychiatric drug development

Experimental & molecular medicine, 2013-11, Vol.45 (11), p.e59-e59

2013

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Deletion of PBP/PPARBP, the Gene for Nuclear Receptor Coactivator Peroxisome Proliferator-activated Receptor-binding Protein, Results in Embryonic Lethality

The Journal of biological chemistry, 2000-05, Vol.275 (20), p.14779-14782

2000

Volltextzugriff (PDF)

CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

Brain (London, England : 1878), 2019-10, Vol.142 (10), p.3243-3264

2019

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Positive and Negative Regulation of the γ-Secretase Activity by Nicastrin in a Murine Model

The Journal of biological chemistry, 2003-08, Vol.278 (35), p.33445-33449

2003

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Requirement of Notch in adulthood for neurological function and longevity

Neuroreport, 2001-10, Vol.12 (15), p.3321-3325

2001

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Steady-State Pharmacokinetics of Galantamine Are Not Affected by Addition of Memantine in Healthy Subjects

Journal of clinical pharmacology, 2005-05, Vol.45 (5), p.519-528

2005

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Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis

Topiramate for Migraine Prevention in Adolescents: A Pooled Analysis of Efficacy and Safety

Long-Term Open-Label Study of Adjunctive Topiramate in Infants With Refractory Partial-Onset Seizures

Adaptive Behavior Outcomes in Infants Treated With Adjunctive Topiramate

Radial Glial Identity Is Promoted by Notch1 Signaling in the Murine Forebrain

Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells

Intracellular Retention of Caveolin 1 in Presenilin-deficient Cells

Alzheimer's disease research and development: a call for a new research roadmap

Effects of galantamine in a 2-year, randomized, placebo-controlled study in Alzheimer's disease

Identification and Characterization of Presenilin-independent Notch Signaling

Effect of concomitant use of memantine on mortality and efficacy outcomes of galantamine-treated patients with Alzheimer's disease: post-hoc analysis of a randomized placebo-controlled study

Pharmacokinetic–pharmacodynamic assessment of topiramate dosing regimens for children with epilepsy 2 to <10 years of age

Changes in gamma-secretase activity and specificity caused by the introduction of consensus aspartyl protease active motif in Presenilin 1

Modeling complex neuropsychiatric disorders with human induced pluripotent stem cells

Evaluation of JNJ-26489112 in patients with photosensitive epilepsy: A placebo-controlled, exploratory study

Spatiotemporal selectivity of response to Notch1 signals in mammalian forebrain precursors

The effect of galantamine on brain atrophy rate in subjects with mild cognitive impairment is modified by apolipoprotein E genotype: post-hoc analysis of data from a randomized controlled trial

Signal Transduction by Activated mNotch: Importance of Proteolytic Processing and its Regulation by the Extracellular Domain

The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD

Implications and limitations of cellular reprogramming for psychiatric drug development

Deletion of PBP/PPARBP, the Gene for Nuclear Receptor Coactivator Peroxisome Proliferator-activated Receptor-binding Protein, Results in Embryonic Lethality

CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

Positive and Negative Regulation of the γ-Secretase Activity by Nicastrin in a Murine Model

Requirement of Notch in adulthood for neurological function and longevity

Steady-State Pharmacokinetics of Galantamine Are Not Affected by Addition of Memantine in Healthy Subjects

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