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A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine

PLoS pathogens, 2017-10, Vol.13 (10), p.e1006682-e1006682

2017

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Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/CD169

PloS one, 2012-06, Vol.7 (6), p.e39039

2012

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Therapeutic Targeting of Siglecs using Antibody- and Glycan-Based Approaches

Trends in pharmacological sciences (Regular ed.), 2015-10, Vol.36 (10), p.645-660

2015

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Probing the binding specificities of human Siglecs by cell-based glycan arrays

Proceedings of the National Academy of Sciences - PNAS, 2021-04, Vol.118 (17), p.1

2021

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Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis

The Journal of clinical investigation, 2013-07, Vol.123 (7), p.3074-3083

2013

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Structural Characterization of the Hemagglutinin Receptor Specificity from the 2009 H1N1 Influenza Pandemic

Journal of Virology, 2012-01, Vol.86 (2), p.982-990

2012

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Major antigenic site B of human influenza H3N2 viruses has an evolving local fitness landscape

Nature communications, 2020-03, Vol.11 (1), p.1233-1233, Article 1233

2020

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Preferential Recognition of Avian-Like Receptors in Human Influenza A H7N9 Viruses

Science (American Association for the Advancement of Science), 2013-12, Vol.342 (6163), p.1230-1235

2013

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Siglec-8 and Siglec-9 binding specificities and endogenous airway ligand distributions and properties

Glycobiology (Oxford), 2017-07, Vol.27 (7), p.657-668

2017

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Mechanistic Investigation and Multiplexing of Liposome-Assisted Metabolic Glycan Labeling

Journal of the American Chemical Society, 2018-03, Vol.140 (10), p.3592-3602

2018

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A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site

Nature communications, 2018-03, Vol.9 (1), p.1264-13, Article 1264

2018

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In Silico-Aided Design of a Glycan Ligand of Sialoadhesin for in Vivo Targeting of Macrophages

Journal of the American Chemical Society, 2012-09, Vol.134 (38), p.15696-15699

2012

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Influenza Virus Neuraminidases with Reduced Enzymatic Activity That Avidly Bind Sialic Acid Receptors

Journal of Virology, 2012-12, Vol.86 (24), p.13371-13383

2012

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Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation

Proceedings of the National Academy of Sciences - PNAS, 2013-05, Vol.110 (19), p.7826-7831

2013

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Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin

Cell host & microbe, 2017-06, Vol.21 (6), p.742-753.e8

2017

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Preventing an Antigenically Disruptive Mutation in Egg-Based H3N2 Seasonal Influenza Vaccines by Mutational Incompatibility

Cell host & microbe, 2019-06, Vol.25 (6), p.836-844.e5

2019

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Encapsulating an Immunosuppressant Enhances Tolerance Induction by Siglec‐Engaging Tolerogenic Liposomes

Chembiochem : a European journal of chemical biology, 2017-07, Vol.18 (13), p.1226-1233

2017

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Murine Red Blood Cells Lack Ligands for B Cell Siglecs, Allowing Strong Activation by Erythrocyte Surface Antigens

The Journal of immunology (1950), 2018-02, Vol.200 (3), p.949-956

2018

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Recognition of Sialylated Poly-N-acetyllactosamine Chains on N- and O-Linked Glycans by Human and Avian Influenza A Virus Hemagglutinins

Angewandte Chemie (International ed.), 2012-05, Vol.51 (20), p.4860-4863

2012

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Unique Structural Features of Influenza Virus H15 Hemagglutinin

Journal of virology, 2017-06, Vol.91 (12)

2017

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Chemoenzymatic Synthesis of Sulfated N‑Glycans Recognized by Siglecs and Other Glycan-Binding Proteins

JACS Au, 2024-08, Vol.4 (8), p.2966-2978

2024

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Targeted Delivery of Antigen to Activated CD169 + Macrophages Induces Bias for Expansion of CD8 + T Cells

Cell chemical biology, 2019-01, Vol.26 (1), p.131-136.e4

2019

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CD33 recruitment inhibits IgE-mediated anaphylaxis and desensitizes mast cells to allergen

The Journal of clinical investigation, 2019-03, Vol.129 (3), p.1387-1401

2019

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Nanoparticles Displaying Allergen and Siglec-8 Ligands Suppress IgE-FcεRI-Mediated Anaphylaxis and Desensitize Mast Cells to Subsequent Antigen Challenge

The Journal of immunology (1950), 2021-05, Vol.206 (10), p.2290-2300

2021

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High affinity sialoside ligands of myelin associated glycoprotein

Bioorganic & medicinal chemistry letters, 2011-09, Vol.21 (17), p.5045-5049

2011

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A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine

Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/CD169

Therapeutic Targeting of Siglecs using Antibody- and Glycan-Based Approaches

Probing the binding specificities of human Siglecs by cell-based glycan arrays

Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis

Structural Characterization of the Hemagglutinin Receptor Specificity from the 2009 H1N1 Influenza Pandemic

Major antigenic site B of human influenza H3N2 viruses has an evolving local fitness landscape

Preferential Recognition of Avian-Like Receptors in Human Influenza A H7N9 Viruses

Siglec-8 and Siglec-9 binding specificities and endogenous airway ligand distributions and properties

Mechanistic Investigation and Multiplexing of Liposome-Assisted Metabolic Glycan Labeling

A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site

In Silico-Aided Design of a Glycan Ligand of Sialoadhesin for in Vivo Targeting of Macrophages

Influenza Virus Neuraminidases with Reduced Enzymatic Activity That Avidly Bind Sialic Acid Receptors

Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation

Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin

Preventing an Antigenically Disruptive Mutation in Egg-Based H3N2 Seasonal Influenza Vaccines by Mutational Incompatibility

Encapsulating an Immunosuppressant Enhances Tolerance Induction by Siglec‐Engaging Tolerogenic Liposomes

Murine Red Blood Cells Lack Ligands for B Cell Siglecs, Allowing Strong Activation by Erythrocyte Surface Antigens

Recognition of Sialylated Poly-N-acetyllactosamine Chains on N- and O-Linked Glycans by Human and Avian Influenza A Virus Hemagglutinins

Unique Structural Features of Influenza Virus H15 Hemagglutinin

Chemoenzymatic Synthesis of Sulfated N‑Glycans Recognized by Siglecs and Other Glycan-Binding Proteins

Targeted Delivery of Antigen to Activated CD169 + Macrophages Induces Bias for Expansion of CD8 + T Cells

CD33 recruitment inhibits IgE-mediated anaphylaxis and desensitizes mast cells to allergen

Nanoparticles Displaying Allergen and Siglec-8 Ligands Suppress IgE-FcεRI-Mediated Anaphylaxis and Desensitize Mast Cells to Subsequent Antigen Challenge

High affinity sialoside ligands of myelin associated glycoprotein

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