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Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients

Circulation (New York, N.Y.), 2005-03, Vol.111 (8), p.1012-1018

2005

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Activity Assays and Immunoassays for Plasma Renin and Prorenin: Information Provided and Precautions Necessary for Accurate Measurement

Clinical chemistry (Baltimore, Md.), 2009-05, Vol.55 (5), p.867-877

2009

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Effect of immunisation against angiotensin II with CYT006-AngQb on ambulatory blood pressure: a double-blind, randomised, placebo-controlled phase IIa study

The Lancet (British edition), 2008-03, Vol.371 (9615), p.821-827

2008

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Treatment of acute edema attacks in hereditary angioedema with a bradykinin receptor-2 antagonist (Icatibant)

Journal of allergy and clinical immunology, 2007-06, Vol.119 (6), p.1497-1503

2007

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A vaccine for hypertension based on virus-like particles: preclinical efficacy and phase I safety and immunogenicity

Journal of hypertension, 2007-01, Vol.25 (1), p.63-72

2007

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The Role of Bradykinin B1 and B2 Receptors for Secondary Brain Damage after Traumatic Brain Injury in Mice

Journal of cerebral blood flow and metabolism, 2010-01, Vol.30 (1), p.130-139

2010

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Angiotensin-Converting Enzyme Inhibition Improves Vascular Function in Rheumatoid Arthritis

Circulation (New York, N.Y.), 2008-04, Vol.117 (17), p.2262-2269

2008

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Expression and functional role of the prorenin receptor in the human adrenocortical zona glomerulosa and in primary aldosteronism

Journal of hypertension, 2015-05, Vol.33 (5), p.1014-1022

2015

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Intravital microscopy reveals endothelial dysfunction in resistance arterioles in Angiotensin II-induced hypertension

Hypertension research, 2012-08, Vol.35 (8), p.855-861

2012

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Systemic and tissue-specific effects of aliskiren on the RAAS and carbohydrate/lipid metabolism in obese patients with hypertension

Journal of the American Society of Hypertension, 2017-08, Vol.11 (8), p.488-497

2017

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The renin prosequence enhances constitutive secretion of renin and optimizes renin activity

Current neurovascular research, 2011-05, Vol.8 (2), p.121-130

2011

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Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity

European heart journal, 2013-12, Vol.34 (45), p.3515-3524

2013

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SFE/SFHTA/AFCE Consensus on Primary Aldosteronism, part 2: First diagnostic steps

Annales d'endocrinologie, 2016-07, Vol.77 (3), p.192-201

2016

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Blood Pressure Lowering in Essential Hypertension With an Oral Renin Inhibitor, Aliskiren

Hypertension (Dallas, Tex. 1979), 2003-12, Vol.42 (6), p.1137-1143

2003

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Aliskiren Reduces Blood Pressure and Suppresses Plasma Renin Activity in Combination With a Thiazide Diuretic, an Angiotensin-Converting Enzyme Inhibitor, or an Angiotensin Receptor Blocker

Hypertension (Dallas, Tex. 1979), 2007-02, Vol.49 (2), p.276-284

2007

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Renin inhibition with aliskiren : where are we now, and where are we going?

Journal of hypertension, 2006-02, Vol.24 (2), p.243-256

2006

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Renin Inhibition by Aliskiren Prevents Atherosclerosis Progression: Comparison With Irbesartan, Atenolol, and Amlodipine

Hypertension (Dallas, Tex. 1979), 2008-05, Vol.51 (5), p.1306-1311

2008

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Vasopressin V 1a Receptors Mediate Posthemorrhagic Systemic Hypertension Thereby Determining Rebleeding Rate and Outcome After Experimental Subarachnoid Hemorrhage

Stroke (1970), 2012-01, Vol.43 (1), p.227-232

2012

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Bradykinin-Mediated Angioedema

The New England journal of medicine, 2002-08, Vol.347 (8), p.621-622

2002

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Acetaminophen Increases Blood Pressure in Patients With Coronary Artery Disease

Circulation (New York, N.Y.), 2010-11, Vol.122 (18), p.1789-1796

2010

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Intraneuronal angiotensinergic system in rat and human dorsal root ganglia

Regulatory peptides, 2010-06, Vol.162 (1), p.90-98

2010

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Are ACE inhibitors acceptable ingredients in polypills?

The Lancet (British edition), 2017-07, Vol.390 (10089), p.26-26

2017

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Angiotensin II Suppression in Humans by the Orally Active Renin Inhibitor Aliskiren (SPP100): Comparison With Enalapril

Hypertension (Dallas, Tex. 1979), 2002-01, Vol.39 (1), p.e1-e8

2002

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Bradykinin in blood and cerebrospinal fluid after acute cerebral lesions: correlations with cerebral edema and intracranial pressure

Journal of neurotrauma, 2013-10, Vol.30 (19), p.1638-1644

2013

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Optimal blockade of the renin–angiotensin–aldosterone system

Nature reviews cardiology, 2013-04, Vol.10 (4), p.183-184

2013

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Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients

Activity Assays and Immunoassays for Plasma Renin and Prorenin: Information Provided and Precautions Necessary for Accurate Measurement

Effect of immunisation against angiotensin II with CYT006-AngQb on ambulatory blood pressure: a double-blind, randomised, placebo-controlled phase IIa study

Treatment of acute edema attacks in hereditary angioedema with a bradykinin receptor-2 antagonist (Icatibant)

A vaccine for hypertension based on virus-like particles: preclinical efficacy and phase I safety and immunogenicity

The Role of Bradykinin B1 and B2 Receptors for Secondary Brain Damage after Traumatic Brain Injury in Mice

Angiotensin-Converting Enzyme Inhibition Improves Vascular Function in Rheumatoid Arthritis

Expression and functional role of the prorenin receptor in the human adrenocortical zona glomerulosa and in primary aldosteronism

Intravital microscopy reveals endothelial dysfunction in resistance arterioles in Angiotensin II-induced hypertension

Systemic and tissue-specific effects of aliskiren on the RAAS and carbohydrate/lipid metabolism in obese patients with hypertension

The renin prosequence enhances constitutive secretion of renin and optimizes renin activity

Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity

SFE/SFHTA/AFCE Consensus on Primary Aldosteronism, part 2: First diagnostic steps

Blood Pressure Lowering in Essential Hypertension With an Oral Renin Inhibitor, Aliskiren

Aliskiren Reduces Blood Pressure and Suppresses Plasma Renin Activity in Combination With a Thiazide Diuretic, an Angiotensin-Converting Enzyme Inhibitor, or an Angiotensin Receptor Blocker

Renin inhibition with aliskiren : where are we now, and where are we going?

Renin Inhibition by Aliskiren Prevents Atherosclerosis Progression: Comparison With Irbesartan, Atenolol, and Amlodipine

Vasopressin V 1a Receptors Mediate Posthemorrhagic Systemic Hypertension Thereby Determining Rebleeding Rate and Outcome After Experimental Subarachnoid Hemorrhage

Bradykinin-Mediated Angioedema

Acetaminophen Increases Blood Pressure in Patients With Coronary Artery Disease

Intraneuronal angiotensinergic system in rat and human dorsal root ganglia

Are ACE inhibitors acceptable ingredients in polypills?

Angiotensin II Suppression in Humans by the Orally Active Renin Inhibitor Aliskiren (SPP100): Comparison With Enalapril

Bradykinin in blood and cerebrospinal fluid after acute cerebral lesions: correlations with cerebral edema and intracranial pressure

Optimal blockade of the renin–angiotensin–aldosterone system

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