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Fusogenic structural changes in arenavirus glycoproteins are associated with viroporin activity

PLoS pathogens, 2023-07, Vol.19 (7), p.e1011217-e1011217

2023

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Second-Generation Live-Attenuated Candid#1 Vaccine Virus Resists Reversion and Protects against Lethal Junín Virus Infection in Guinea Pigs

Journal of virology, 2021-06, Vol.95 (14), p.e0039721-e0039721

2021

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Arenavirus Infection Induces Discrete Cytosolic Structures for RNA Replication

Journal of Virology, 2012-10, Vol.86 (20), p.11301-11310

2012

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Role of the Stable Signal Peptide of Junín Arenavirus Envelope Glycoprotein in pH-Dependent Membrane Fusion

Journal of Virology, 2006-08, Vol.80 (15), p.7775-7780

2006

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Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses

Nature, 2007-03, Vol.446 (7131), p.92-96

2007

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Intersubunit Interactions Modulate pH-Induced Activation of Membrane Fusion by the Junín Virus Envelope Glycoprotein GPC

Journal of Virology, 2009-05, Vol.83 (9), p.4121-4126

2009

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Dissection of the Role of the Stable Signal Peptide of the Arenavirus Envelope Glycoprotein in Membrane Fusion

Journal of Virology, 2012-06, Vol.86 (11), p.6138-6145

2012

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pH-Induced Activation of Arenavirus Membrane Fusion Is Antagonized by Small-Molecule Inhibitors

Journal of Virology, 2008-11, Vol.82 (21), p.10932-10939

2008

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T-705 (Favipiravir) Inhibition of Arenavirus Replication in Cell Culture

Antimicrobial Agents and Chemotherapy, 2011-02, Vol.55 (2), p.782-787

2011

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A Novel Zinc-Binding Domain Is Essential for Formation of the Functional Junín Virus Envelope Glycoprotein Complex

Journal of Virology, 2007-12, Vol.81 (24), p.13385-13391

2007

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The Signal Peptide of the Junín Arenavirus Envelope Glycoprotein Is Myristoylated and Forms an Essential Subunit of the Mature G1-G2 Complex

Journal of Virology, 2004-10, Vol.78 (19), p.10783-10792

2004

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Distinct requirements for signal peptidase processing and function in the stable signal peptide subunit of the Junín virus envelope glycoprotein

Virology (New York, N.Y.), 2007-03, Vol.359 (1), p.72-81

2007

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Epistastic Interactions within the Junín Virus Envelope Glycoprotein Complex Provide an Evolutionary Barrier to Reversion in the Live-Attenuated Candid#1 Vaccine

Journal of virology, 2018-01, Vol.92 (1)

2018

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Role of the Stable Signal Peptide and Cytoplasmic Domain of G2 in Regulating Intracellular Transport of the Junín Virus Envelope Glycoprotein Complex

Journal of Virology, 2006-06, Vol.80 (11), p.5189-5198

2006

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Myristoylation of the Arenavirus Envelope Glycoprotein Stable Signal Peptide Is Critical for Membrane Fusion but Dispensable for Virion Morphogenesis

Journal of virology, 2016-09, Vol.90 (18), p.8341-8350

2016

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Unique Small Molecule Entry Inhibitors of Hemorrhagic Fever Arenaviruses

The Journal of biological chemistry, 2008-07, Vol.283 (27), p.18734-18742

2008

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Bitopic Membrane Topology of the Stable Signal Peptide in the Tripartite Junín Virus GP-C Envelope Glycoprotein Complex

Journal of Virology, 2007-04, Vol.81 (8), p.4331-4337

2007

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Biochemical reconstitution of hemorrhagic-fever arenavirus envelope glycoprotein-mediated membrane fusion

PloS one, 2012-11, Vol.7 (11), p.e51114-e51114

2012

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An Antibody Directed against the Fusion Peptide of Junín Virus Envelope Glycoprotein GPC Inhibits pH-Induced Membrane Fusion

Journal of Virology, 2010-06, Vol.84 (12), p.6119-6129

2010

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Restoration of virulence in the attenuated Candid#1 vaccine virus requires reversion at both positions 168 and 427 in the envelope glycoprotein GPC

Journal of virology, 2024-04, Vol.98 (4), p.e0011224

2024

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Role of Hydrophobic Residues in the Central Ectodomain of gp41 in Maintaining the Association between Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Subunits gp120 and gp41

Journal of Virology, 2004-05, Vol.78 (9), p.4921-4926

2004

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Oligomerization of Hepatitis C Virus Core Protein Is Crucial for Interaction with the Cytoplasmic Domain of E1 Envelope Protein

Journal of Virology, 2006-11, Vol.80 (22), p.11265-11273

2006

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Furin cleavage of the SARS coronavirus spike glycoprotein enhances cell–cell fusion but does not affect virion entry

Virology (New York, N.Y.), 2006-07, Vol.350 (2), p.358-369

2006

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Small-Molecule Fusion Inhibitors Bind the pH-Sensing Stable Signal Peptide-GP2 Subunit Interface of the Lassa Virus Envelope Glycoprotein

Journal of virology, 2016-08, Vol.90 (15), p.6799-6807

2016

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Assembly of Arenavirus Envelope Glycoprotein GPC in Detergent-Soluble Membrane Microdomains

Journal of Virology, 2009-10, Vol.83 (19), p.9890-9900

2009

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Fusogenic structural changes in arenavirus glycoproteins are associated with viroporin activity

Second-Generation Live-Attenuated Candid#1 Vaccine Virus Resists Reversion and Protects against Lethal Junín Virus Infection in Guinea Pigs

Arenavirus Infection Induces Discrete Cytosolic Structures for RNA Replication

Role of the Stable Signal Peptide of Junín Arenavirus Envelope Glycoprotein in pH-Dependent Membrane Fusion

Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses

Intersubunit Interactions Modulate pH-Induced Activation of Membrane Fusion by the Junín Virus Envelope Glycoprotein GPC

Dissection of the Role of the Stable Signal Peptide of the Arenavirus Envelope Glycoprotein in Membrane Fusion

pH-Induced Activation of Arenavirus Membrane Fusion Is Antagonized by Small-Molecule Inhibitors

T-705 (Favipiravir) Inhibition of Arenavirus Replication in Cell Culture

A Novel Zinc-Binding Domain Is Essential for Formation of the Functional Junín Virus Envelope Glycoprotein Complex

The Signal Peptide of the Junín Arenavirus Envelope Glycoprotein Is Myristoylated and Forms an Essential Subunit of the Mature G1-G2 Complex

Distinct requirements for signal peptidase processing and function in the stable signal peptide subunit of the Junín virus envelope glycoprotein

Epistastic Interactions within the Junín Virus Envelope Glycoprotein Complex Provide an Evolutionary Barrier to Reversion in the Live-Attenuated Candid#1 Vaccine

Role of the Stable Signal Peptide and Cytoplasmic Domain of G2 in Regulating Intracellular Transport of the Junín Virus Envelope Glycoprotein Complex

Myristoylation of the Arenavirus Envelope Glycoprotein Stable Signal Peptide Is Critical for Membrane Fusion but Dispensable for Virion Morphogenesis

Unique Small Molecule Entry Inhibitors of Hemorrhagic Fever Arenaviruses

Bitopic Membrane Topology of the Stable Signal Peptide in the Tripartite Junín Virus GP-C Envelope Glycoprotein Complex

Biochemical reconstitution of hemorrhagic-fever arenavirus envelope glycoprotein-mediated membrane fusion

An Antibody Directed against the Fusion Peptide of Junín Virus Envelope Glycoprotein GPC Inhibits pH-Induced Membrane Fusion

Restoration of virulence in the attenuated Candid#1 vaccine virus requires reversion at both positions 168 and 427 in the envelope glycoprotein GPC

Role of Hydrophobic Residues in the Central Ectodomain of gp41 in Maintaining the Association between Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Subunits gp120 and gp41

Oligomerization of Hepatitis C Virus Core Protein Is Crucial for Interaction with the Cytoplasmic Domain of E1 Envelope Protein

Furin cleavage of the SARS coronavirus spike glycoprotein enhances cell–cell fusion but does not affect virion entry

Small-Molecule Fusion Inhibitors Bind the pH-Sensing Stable Signal Peptide-GP2 Subunit Interface of the Lassa Virus Envelope Glycoprotein

Assembly of Arenavirus Envelope Glycoprotein GPC in Detergent-Soluble Membrane Microdomains

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