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Drug Insight: tumor necrosis factor-converting enzyme as a pharmaceutical target for rheumatoid arthritis

Nature clinical practice. Rheumatology, 2008-06, Vol.4 (6), p.300-309

2008

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An Integrated in Silico 3D Model-Driven Discovery of a Novel, Potent, and Selective Amidosulfonamide 5-HT1A Agonist (PRX-00023) for the Treatment of Anxiety and Depression

Journal of medicinal chemistry, 2006-06, Vol.49 (11), p.3116-3135

2006

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A Nitric Oxide Processing Defect of Red Blood Cells Created by Hypoxia: Deficiency of S-Nitrosohemoglobin in Pulmonary Hypertension

Proceedings of the National Academy of Sciences - PNAS, 2005-10, Vol.102 (41), p.14801-14806

2005

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Fluorescent substrates useful as high-throughput screening tools for ADAM9

Combinatorial chemistry & high throughput screening, 2010-05, Vol.13 (4), p.358-365

2010

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Evaluation of the nitrosamine impurities of ACE inhibitors using computational, in vitro, and in vivo methods demonstrate no genotoxic potential

Environmental and molecular mutagenesis, 2024-08, Vol.65 (6-7), p.203-221

2024

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The Nitrosamine “Saga”: Lessons Learned from Five Years of Scrutiny

Organic process research & development, 2023-10, Vol.27 (10), p.1719-1735

2023

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N-Nitrosamine Drug Substance Related Impurities (NDSRIs) – A proposal for the addition of subcategories to Carcinogenic Potency Categorisation Approach categories 1 and 2 for NDSRIs with a molecular weight > 200 Da

Regulatory toxicology and pharmacology, 2024-09, p.105704, Article 105704

2024

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Assessing the utility of common arguments used in expert review of in silico predictions as part of ICH M7 assessments

Regulatory toxicology and pharmacology, 2023-10, Vol.144, p.105490-105490, Article 105490

2023

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Qualification of impurities based on metabolite data

Regulatory toxicology and pharmacology, 2020-02, Vol.110, p.104524, Article 104524

2020

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Iron uptake in Ustilago maydis: tracking the iron path

Journal of Bacteriology, 1998-04, Vol.180 (8), p.2021-2026

1998

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OxyR: A Molecular Code for Redox-Related Signaling

Cell, 2002-05, Vol.109 (3), p.383-396

2002

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S -nitrosylation: spectrum and specificity

Nature cell biology, 2001-02, Vol.3 (2), p.E46-E49

2001

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ICH M7 – Assessment and Control of DNA Reactive (Mutagenic) Impurities in Pharmaceuticals to Limit Potential Carcinogenic Risk

Mutagenic Impurities, 2021, p.21-56

2021

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Modular Fluorescent-Labeled Siderophore Analogues

Journal of medicinal chemistry, 1998-05, Vol.41 (10), p.1671-1678

1998

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An Integrated in Silico 3D Model-Driven Discovery of a Novel, Potent, and Selective Amidosulfonamide 5-HT 1A Agonist (PRX-00023) for the Treatment of Anxiety and Depression

Journal of medicinal chemistry, 2006-06, Vol.49 (11), p.3116-3135

2006

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In vivo and in vitro elimination of aliphatic polyanhydrides

Biomaterials, 1995-03, Vol.16 (4), p.319-323

1995

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OxyR

Cell, 2002-05, Vol.109 (3), p.383-396

2002

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Biomimetic siderophore derivatives as diagnostic tools for the detection and identification of microorganisms and as antimicrobial targeting agents

Nudelman, Raphael

1998

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Chemical interactions between drugs containing reactive amines with hydrolyzable insoluble biopolymers in aqueous solutions

Pharmaceutical research, 1994-06, Vol.11 (6), p.865-868

1994

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Simulation of fractograms of fat emulsions in power-programmed sedimentation field-flow fractionation (SdFFF)

Journal of pharmaceutical and biomedical analysis, 1995-06, Vol.13 (7), p.869-877

1995

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Biodegradable polymers derived from natural fatty acids

Journal of polymer science. Part A, Polymer chemistry, 1995-03, Vol.33 (4), p.717-725

1995

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Bowel Obstruction From Biliary Stent Migration: An Unusual Case of Abdominal Pain

Curēus (Palo Alto, CA), 2024-01

2024

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Oral Potassium Malabsorption Following Bariatric Surgery

Curēus (Palo Alto, CA), 2022-08

2022

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Superficial Siderosis After Traumatic Brain Injury: A Case Report

Curēus (Palo Alto, CA), 2024-03

2024

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Changing trends in surgery for acute cholecystitis

World journal of surgery, 1990-09, Vol.14 (5), p.567-570

1990

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Drug Insight: tumor necrosis factor-converting enzyme as a pharmaceutical target for rheumatoid arthritis

An Integrated in Silico 3D Model-Driven Discovery of a Novel, Potent, and Selective Amidosulfonamide 5-HT1A Agonist (PRX-00023) for the Treatment of Anxiety and Depression

A Nitric Oxide Processing Defect of Red Blood Cells Created by Hypoxia: Deficiency of S-Nitrosohemoglobin in Pulmonary Hypertension

Fluorescent substrates useful as high-throughput screening tools for ADAM9

Evaluation of the nitrosamine impurities of ACE inhibitors using computational, in vitro, and in vivo methods demonstrate no genotoxic potential

The Nitrosamine “Saga”: Lessons Learned from Five Years of Scrutiny

N-Nitrosamine Drug Substance Related Impurities (NDSRIs) – A proposal for the addition of subcategories to Carcinogenic Potency Categorisation Approach categories 1 and 2 for NDSRIs with a molecular weight > 200 Da

Assessing the utility of common arguments used in expert review of in silico predictions as part of ICH M7 assessments

Qualification of impurities based on metabolite data

Iron uptake in Ustilago maydis: tracking the iron path

OxyR: A Molecular Code for Redox-Related Signaling

S -nitrosylation: spectrum and specificity

ICH M7 – Assessment and Control of DNA Reactive (Mutagenic) Impurities in Pharmaceuticals to Limit Potential Carcinogenic Risk

Modular Fluorescent-Labeled Siderophore Analogues

An Integrated in Silico 3D Model-Driven Discovery of a Novel, Potent, and Selective Amidosulfonamide 5-HT 1A Agonist (PRX-00023) for the Treatment of Anxiety and Depression

In vivo and in vitro elimination of aliphatic polyanhydrides

OxyR

Biomimetic siderophore derivatives as diagnostic tools for the detection and identification of microorganisms and as antimicrobial targeting agents

Chemical interactions between drugs containing reactive amines with hydrolyzable insoluble biopolymers in aqueous solutions

Simulation of fractograms of fat emulsions in power-programmed sedimentation field-flow fractionation (SdFFF)

Biodegradable polymers derived from natural fatty acids

Bowel Obstruction From Biliary Stent Migration: An Unusual Case of Abdominal Pain

Oral Potassium Malabsorption Following Bariatric Surgery

Superficial Siderosis After Traumatic Brain Injury: A Case Report

Changing trends in surgery for acute cholecystitis

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