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Insulinoma-Associated-1: From Neuroendocrine Tumor Marker to Cancer Therapeutics

Molecular cancer research, 2019-08, Vol.17 (8), p.1597-1604

2019

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Polyreactive IgM initiates complement activation by PF4/heparin complexes through the classical pathway

Blood, 2018-12, Vol.132 (23), p.2431-2440

2018

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Stimulation of Toll-Like Receptors profoundly influences the titer of polyreactive antibodies in the circulation

Scientific reports, 2015-10, Vol.5 (1), p.15066-15066, Article 15066

2015

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Targeted deletion of Insm2 in mice result in reduced insulin secretion and glucose intolerance

Journal of translational medicine, 2018-10, Vol.16 (1), p.297-297, Article 297

2018

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Ultrarapid Measurement of Diagnostic Antibodies by Magnetic Capture of Immune Complexes

Scientific reports, 2017-06, Vol.7 (1), p.3818-11, Article 3818

2017

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Partial reconstitution of humoral immunity and fewer infections in patients with chronic lymphocytic leukemia treated with ibrutinib

Blood, 2015-11, Vol.126 (19), p.2213-2219

2015

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Luciferase-Based Detection of Antibodies for the Diagnosis of HPV-Associated Head and Neck Squamous Cell Carcinoma

Diagnostics (Basel), 2019-08, Vol.9 (3), p.89

2019

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Luciferase immunoprecipitation systems for measuring antibodies in autoimmune and infectious diseases

Translational research : the journal of laboratory and clinical medicine, 2015-02, Vol.165 (2), p.325-335

2015

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The Ia-2β intronic miRNA, miR-153, is a negative regulator of insulin and dopamine secretion through its effect on the Cacna1c gene in mice

Diabetologia, 2015-10, Vol.58 (10), p.2298-2306

2015

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Multiple microRNAs within the 14q32 cluster target the mRNAs of major type 1 diabetes autoantigens IA‐2, IA‐2β, and GAD65

The FASEB journal, 2015-10, Vol.29 (10), p.4374-4383

2015

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Loss of the transcriptional repressor PAG-3/Gfi-1 results in enhanced neurosecretion that is dependent on the dense-core vesicle membrane protein IDA-1/IA-2

PLoS genetics, 2009-04, Vol.5 (4), p.e1000447-e1000447

2009

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Impact of natural IgM concentration on gene therapy with adenovirus type 5 vectors

Journal of virology, 2015-03, Vol.89 (6), p.3412-3416

2015

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Pathophysiologic changes in IA-2/IA-2β null mice are secondary to alterations in the secretion of hormones and neurotransmitters

Acta diabetologica, 2016-02, Vol.53 (1), p.7-12

2016

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Small cell lung cancer growth is inhibited by miR-342 through its effect of the target gene IA-2

Journal of translational medicine, 2016-09, Vol.14 (1), p.278-278, Article 278

2016

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RESP18, a homolog of the luminal domain IA-2, is found in dense core vesicles in pancreatic islet cells and is induced by high glucose

Journal of endocrinology, 2007-11, Vol.195 (2), p.313-321

2007

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Neutralizing the Impact Factor Culture

Science (American Association for the Advancement of Science), 2008-10, Vol.322 (5899), p.191-191

Notkins, Abner L.

2008

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Polyreactive Antibodies Plus Complement Enhance the Phagocytosis of Cells Made Apoptotic by UV-Light or HIV

Scientific reports, 2013-07, Vol.3 (1), p.2271, Article 2271

2013

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Polyreactive antibodies in CLL correlate with the level of immunoglobulins not the number of B lymphocytes

Leukemia & lymphoma, 2019-01, Vol.60 (1), p.242-245

2019

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The minimal promoter region of the dense-core vesicle protein IA-2: transcriptional regulation by CREB

Acta diabetologica, 2015-06, Vol.52 (3), p.573-580

2015

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Expression of Insulinoma-Associated 2 (INSM2) in Pancreatic Islet Cells Is Regulated by the Transcription Factors Ngn3 and NeuroD1

Endocrinology (Philadelphia), 2011-05, Vol.152 (5), p.1961-1969

2011

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Disruption of gene expression rhythms in mice lacking secretory vesicle proteins IA-2 and IA-2β

American journal of physiology: endocrinology and metabolism, 2012-09, Vol.303 (6), p.E762-E776

2012

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Insulinoma-Associated Protein IA-2, a Vesicle Transmembrane Protein, Genetically Interacts with UNC-31/CAPS and Affects Neurosecretion in Caenorhabditis elegans

The Journal of neuroscience, 2004-03, Vol.24 (12), p.3115-3124

2004

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Comparison of Radioimmunoprecipitation With Luciferase Immunoprecipitation for Autoantibodies to GAD65 and IA-2β

Diabetes care, 2010-04, Vol.33 (4), p.754-756

2010

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Comment on: Torii et al. (2009) Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growth. Diabetes 58:682-692

Diabetes (New York, N.Y.), 2009-05, Vol.58 (5), p.e8-e8

2009

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Deletion of the secretory vesicle proteins IA-2 and IA-2β disrupts circadian rhythms of cardiovascular and physical activity

The FASEB journal, 2009-09, Vol.23 (9), p.3226-3232

2009

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Insulinoma-Associated-1: From Neuroendocrine Tumor Marker to Cancer Therapeutics

Polyreactive IgM initiates complement activation by PF4/heparin complexes through the classical pathway

Stimulation of Toll-Like Receptors profoundly influences the titer of polyreactive antibodies in the circulation

Targeted deletion of Insm2 in mice result in reduced insulin secretion and glucose intolerance

Ultrarapid Measurement of Diagnostic Antibodies by Magnetic Capture of Immune Complexes

Partial reconstitution of humoral immunity and fewer infections in patients with chronic lymphocytic leukemia treated with ibrutinib

Luciferase-Based Detection of Antibodies for the Diagnosis of HPV-Associated Head and Neck Squamous Cell Carcinoma

Luciferase immunoprecipitation systems for measuring antibodies in autoimmune and infectious diseases

The Ia-2β intronic miRNA, miR-153, is a negative regulator of insulin and dopamine secretion through its effect on the Cacna1c gene in mice

Multiple microRNAs within the 14q32 cluster target the mRNAs of major type 1 diabetes autoantigens IA‐2, IA‐2β, and GAD65

Loss of the transcriptional repressor PAG-3/Gfi-1 results in enhanced neurosecretion that is dependent on the dense-core vesicle membrane protein IDA-1/IA-2

Impact of natural IgM concentration on gene therapy with adenovirus type 5 vectors

Pathophysiologic changes in IA-2/IA-2β null mice are secondary to alterations in the secretion of hormones and neurotransmitters

Small cell lung cancer growth is inhibited by miR-342 through its effect of the target gene IA-2

RESP18, a homolog of the luminal domain IA-2, is found in dense core vesicles in pancreatic islet cells and is induced by high glucose

Neutralizing the Impact Factor Culture

Polyreactive Antibodies Plus Complement Enhance the Phagocytosis of Cells Made Apoptotic by UV-Light or HIV

Polyreactive antibodies in CLL correlate with the level of immunoglobulins not the number of B lymphocytes

The minimal promoter region of the dense-core vesicle protein IA-2: transcriptional regulation by CREB

Expression of Insulinoma-Associated 2 (INSM2) in Pancreatic Islet Cells Is Regulated by the Transcription Factors Ngn3 and NeuroD1

Disruption of gene expression rhythms in mice lacking secretory vesicle proteins IA-2 and IA-2β

Insulinoma-Associated Protein IA-2, a Vesicle Transmembrane Protein, Genetically Interacts with UNC-31/CAPS and Affects Neurosecretion in Caenorhabditis elegans

Comparison of Radioimmunoprecipitation With Luciferase Immunoprecipitation for Autoantibodies to GAD65 and IA-2β

Comment on: Torii et al. (2009) Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growth. Diabetes 58:682-692

Deletion of the secretory vesicle proteins IA-2 and IA-2β disrupts circadian rhythms of cardiovascular and physical activity

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