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Modulation of the NGF – TRKA pathway for treatment of joint pain: preclinical in vivo evaluation in mice

OSTEOARTHRITIS AND CARTILAGE, 2018-04, Vol.26, p.S357-S358

2018

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Neurotrophin-targeted therapeutics: A gateway to cognition and more?

Drug discovery today, 2022-10, Vol.27 (10), p.103318-103318, Article 103318

2022

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Small constrained SP1–7 analogs bind to a unique site and promote anti-allodynic effects following systemic injection in mice

Neuroscience, 2015-07, Vol.298, p.112-119

2015

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Gamma-secretase modulators: a promising route for the treatment of Alzheimer's disease

Frontiers in molecular neuroscience, 2023-10, Vol.16, p.1279740-1279740

2023

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Antidepressant effects of novel positive allosteric modulators of Trk-receptor mediated signaling – a potential therapeutic concept?

Psychopharmacology, 2023-08, Vol.240 (8), p.1789-1804

2023

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Neuroprotective and Disease-Modifying Effects of the Triazinetrione ACD856, a Positive Allosteric Modulator of Trk-Receptors for the Treatment of Cognitive Dysfunction in Alzheimer's Disease

International journal of molecular sciences, 2023-07, Vol.24 (13), p.11159

2023

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P.0229 Characterization of positive allosteric modulators of trkb for the treatment of depression

European neuropsychopharmacology, 2021-12, Vol.53, p.S166-S167

2021

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Identification of amino acid residues of nerve growth factor important for neurite outgrowth in human dorsal root ganglion neurons

The European journal of neuroscience, 2019-11, Vol.50 (9), p.3487-3501

2019

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γ‐Secretase modulators show selectivity for γ‐secretase–mediated amyloid precursor protein intramembrane processing

Journal of cellular and molecular medicine, 2022-02, Vol.26 (3), p.880-892

2022

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Identification of Novel Positive Allosteric Modulators of Neurotrophin Receptors for the Treatment of Cognitive Dysfunction

Cells (Basel, Switzerland), 2021-07, Vol.10 (8), p.1871

2021

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Atropisomeric Derivatives of 2‘,6‘-Disubstituted (R)-11-Phenylaporphine: Selective Serotonin 5-HT7 Receptor Antagonists

Journal of medicinal chemistry, 2001-04, Vol.44 (9), p.1337-1340

2001

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Delineation of the peptide binding site of the human galanin receptor

The EMBO journal, 1996-01, Vol.15 (2), p.236-244

1996

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The battle of Alzheimer's Disease - the beginning of the future Unleashing the potential of academic discoveries

Frontiers in pharmacology, 2014, Vol.5, p.102-102

2014

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Molecular basis for the binding of 2-aminotetralins to human dopamine D2A and D3 receptors

Molecular pharmacology, 1994-08, Vol.46 (2), p.299

1994

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A basic peptide within the juxtamembrane region is required for EGF receptor dimerization

Experimental cell research, 2005, Vol.302 (1), p.108-114

2005

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Novel 2-Aminotetralin and 3-AminoChroman Derivatives as Selective Serotonin 5-HT7 Receptor Agonists and Antagonists

Journal of medicinal chemistry, 2004-07, Vol.47 (16), p.3927-3930

2004

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Stimulating Neurotrophin Receptors in the Treatment of Neurodegenerative Disorders

Annual Reports in Medicinal Chemistry, 2014, Vol.49, p.59-73

2014

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Mutagenesis of the Human 5-HT1B Receptor: Differences from the Closely Related 5-HT1A Receptor and the Role of Residue F331 in Signal Transduction

Journal of receptors and signal transduction, 1998-01, Vol.18 (4-6), p.225-241

1998

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Binding-site modeling of the muscarinic m1 receptor: a combination of homology-based and indirect approaches

Journal of medicinal chemistry, 1993-04, Vol.36 (8), p.967-976

1993

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Effector stage CC chemokine receptor-1 selective antagonism reduces multiple sclerosis-like rat disease

Journal of neuroimmunology, 2003-09, Vol.142 (1), p.75-85

2003

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Site-directed mutagenesis of the human 5-HT1B receptor

European journal of pharmacology, 1998-05, Vol.349 (2-3), p.367-375

1998

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Synthesis of Novel 5-Substituted 3-Amino-3,4-dihydro-2H-1-benzopyran Derivatives and Their Interactions with the 5-HT1A Receptor

Journal of medicinal chemistry, 2000-07, Vol.43 (15), p.2837-2850

2000

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AR-A000002, a high affinity 5-HT 1B receptor antagonist: Synthesis and structure-activity relationships

European neuropsychopharmacology, 2001, Vol.11, p.S213-S214

2001

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AR-A000002, a high affinity 5-HT1B receptor antagonist: Synthesis and structure-activity relationships

European neuropsychopharmacology, 2001-01, Vol.11, p.S213-S214

2001

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Atropisomeric derivatives of 2',6'-disubstituted (R)-11-phenylaporphine: selective serotonin 5-HT(7) receptor antagonists

Journal of medicinal chemistry, 2001-04, Vol.44 (9), p.1337-1340

2001

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Modulation of the NGF – TRKA pathway for treatment of joint pain: preclinical in vivo evaluation in mice

Neurotrophin-targeted therapeutics: A gateway to cognition and more?

Small constrained SP1–7 analogs bind to a unique site and promote anti-allodynic effects following systemic injection in mice

Gamma-secretase modulators: a promising route for the treatment of Alzheimer's disease

Antidepressant effects of novel positive allosteric modulators of Trk-receptor mediated signaling – a potential therapeutic concept?

Neuroprotective and Disease-Modifying Effects of the Triazinetrione ACD856, a Positive Allosteric Modulator of Trk-Receptors for the Treatment of Cognitive Dysfunction in Alzheimer's Disease

P.0229 Characterization of positive allosteric modulators of trkb for the treatment of depression

Identification of amino acid residues of nerve growth factor important for neurite outgrowth in human dorsal root ganglion neurons

γ‐Secretase modulators show selectivity for γ‐secretase–mediated amyloid precursor protein intramembrane processing

Identification of Novel Positive Allosteric Modulators of Neurotrophin Receptors for the Treatment of Cognitive Dysfunction

Atropisomeric Derivatives of 2‘,6‘-Disubstituted (R)-11-Phenylaporphine: Selective Serotonin 5-HT7 Receptor Antagonists

Delineation of the peptide binding site of the human galanin receptor

The battle of Alzheimer's Disease - the beginning of the future Unleashing the potential of academic discoveries

Molecular basis for the binding of 2-aminotetralins to human dopamine D2A and D3 receptors

A basic peptide within the juxtamembrane region is required for EGF receptor dimerization

Novel 2-Aminotetralin and 3-AminoChroman Derivatives as Selective Serotonin 5-HT7 Receptor Agonists and Antagonists

Stimulating Neurotrophin Receptors in the Treatment of Neurodegenerative Disorders

Mutagenesis of the Human 5-HT1B Receptor: Differences from the Closely Related 5-HT1A Receptor and the Role of Residue F331 in Signal Transduction

Binding-site modeling of the muscarinic m1 receptor: a combination of homology-based and indirect approaches

Effector stage CC chemokine receptor-1 selective antagonism reduces multiple sclerosis-like rat disease

Site-directed mutagenesis of the human 5-HT1B receptor

Synthesis of Novel 5-Substituted 3-Amino-3,4-dihydro-2H-1-benzopyran Derivatives and Their Interactions with the 5-HT1A Receptor

AR-A000002, a high affinity 5-HT 1B receptor antagonist: Synthesis and structure-activity relationships

AR-A000002, a high affinity 5-HT1B receptor antagonist: Synthesis and structure-activity relationships

Atropisomeric derivatives of 2',6'-disubstituted (R)-11-phenylaporphine: selective serotonin 5-HT(7) receptor antagonists

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