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Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump

Blood, 2004-11, Vol.104 (9), p.2940-2942

2004

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Clinical Pharmacokinetics and Metabolism of Irinotecan (CPT-11)

Clinical cancer research, 2001-08, Vol.7 (8), p.2182-2194

2001

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Pharmacokinetic Resistance to Imatinib Mesylate: Role of the ABC Drug Pumps ABCG2 (BCRP) and ABCB1 (MDR1) in the Oral Bioavailability of Imatinib

Cell cycle (Georgetown, Tex.), 2004-12, Vol.3 (12), p.1502-1505

2004

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Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps

Cancer biology & therapy, 2005-07, Vol.4 (7), p.747-752

2005

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Functional Screen for Genes Responsible for Tamoxifen Resistance in Human Breast Cancer Cells

Molecular cancer research, 2006-06, Vol.4 (6), p.379-386

2006

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Impact of Body-Size Measures on Irinotecan Clearance: Alternative Dosing Recommendations

Journal of clinical oncology, 2002-01, Vol.20 (1), p.81-87

Mathijssen, R. H.J.

2002

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Body-Surface Area–Based Dosing Does Not Increase Accuracy of Predicting Cisplatin Exposure

Journal of clinical oncology, 2001-09, Vol.19 (17), p.3733-3739

2001

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Influence of Cremophor EL on the Bioavailability of Intraperitoneal Paclitaxel

Clinical cancer research, 2002-04, Vol.8 (4), p.1237-1241

2002

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Randomized Cross-Over Evaluation of Body-Surface Area–Based Dosing Versus Flat-Fixed Dosing of Paclitaxel

Journal of clinical oncology, 2003-01, Vol.21 (2), p.197-202

2003

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Role of Intestinal P-glycoprotein in the Plasma and Fecal Disposition of Docetaxel in Humans

Clinical cancer research, 2000-07, Vol.6 (7), p.2598-2603

2000

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Pharmacokinetic modeling of paclitaxel encapsulation in Cremophor EL micelles

Cancer chemotherapy and pharmacology, 2001-04, Vol.47 (4), p.309-318

2001

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Activating mutations in c-KIT and PDGFRα are exclusively found in gastrointestinal stromal tumors and not in other tumors overexpressing these imatinib mesylate target genes

Cancer biology & therapy, 2005-11, Vol.4 (11), p.1270-1274

2005

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Development of multidrug-resistance convertors : sense or nonsense?

Investigational new drugs, 2000-08, Vol.18 (3), p.205-220

2000

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Evaluation of an Alternate Dosing Strategy for Cisplatin in Patients With Extreme Body Surface Area Values

Journal of clinical oncology, 2006-04, Vol.24 (10), p.1499-1506

2006

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Resistance to Platinum-Containing Chemotherapy in Testicular Germ Cell Tumors Is Associated with Downregulation of the Protein Kinase SRPK1

Neoplasia (New York, N.Y.), 2004-07, Vol.6 (4), p.297-301

2004

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Impaired cisplatin influx in an A2780 mutant cell line: Evidence for a putative, cis-configuration-specific, platinum influx transporter

Cancer biology & therapy, 2006-08, Vol.5 (8), p.943-949

2006

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Anticancer Drug Resistance Induced by Disruption of the Saccharomyces cerevisiae NPR2 Gene: a Novel Component Involved in Cisplatin- and Doxorubicin-Provoked Cell Kill

Molecular pharmacology, 2003-08, Vol.64 (2), p.259-268

2003

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Determination of Doxorubicin and Doxorubicinol in Plasma of Cancer Patients by High-Performance Liquid Chromatography

Analytical biochemistry, 1999-01, Vol.266 (2), p.216-221

1999

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RNA Expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: Correlation with chemotherapeutic response

Clinical cancer research, 2003-02, Vol.9 (2), p.827-836

2003

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Quantitation of Cremophor EL in Human Plasma Samples Using a Colorimetric Dye-Binding Microassay

Analytical biochemistry, 1998-01, Vol.255 (2), p.171-175

1998

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Effect of ABCG2 genotype on the oral bioavailability of topotecan

Cancer biology & therapy, 2005-06, Vol.4 (6), p.650-658

2005

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Molecular profiling of platinum resistant ovarian cancer

International journal of cancer, 2006-04, Vol.118 (8), p.1963-1971

2006

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Disposition of [G-(3)H]paclitaxel and cremophor EL in a patient with severely impaired renal function

Drug metabolism and disposition, 1999-11, Vol.27 (11), p.1300

1999

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Effect of ABCG2 genotype on the oral vioavailability of topotecan

Cancer biology & therapy, 2005-06, Vol.4 (6), p.650-653

2005

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Association of enzyme and transporter genotypes with the pharmacokinetics of imatinib

Clinical pharmacology and therapeutics, 2006-08, Vol.80 (2), p.192-201

2006

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Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump

Clinical Pharmacokinetics and Metabolism of Irinotecan (CPT-11)

Pharmacokinetic Resistance to Imatinib Mesylate: Role of the ABC Drug Pumps ABCG2 (BCRP) and ABCB1 (MDR1) in the Oral Bioavailability of Imatinib

Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps

Functional Screen for Genes Responsible for Tamoxifen Resistance in Human Breast Cancer Cells

Impact of Body-Size Measures on Irinotecan Clearance: Alternative Dosing Recommendations

Body-Surface Area–Based Dosing Does Not Increase Accuracy of Predicting Cisplatin Exposure

Influence of Cremophor EL on the Bioavailability of Intraperitoneal Paclitaxel

Randomized Cross-Over Evaluation of Body-Surface Area–Based Dosing Versus Flat-Fixed Dosing of Paclitaxel

Role of Intestinal P-glycoprotein in the Plasma and Fecal Disposition of Docetaxel in Humans

Pharmacokinetic modeling of paclitaxel encapsulation in Cremophor EL micelles

Activating mutations in c-KIT and PDGFRα are exclusively found in gastrointestinal stromal tumors and not in other tumors overexpressing these imatinib mesylate target genes

Development of multidrug-resistance convertors : sense or nonsense?

Evaluation of an Alternate Dosing Strategy for Cisplatin in Patients With Extreme Body Surface Area Values

Resistance to Platinum-Containing Chemotherapy in Testicular Germ Cell Tumors Is Associated with Downregulation of the Protein Kinase SRPK1

Impaired cisplatin influx in an A2780 mutant cell line: Evidence for a putative, cis-configuration-specific, platinum influx transporter

Anticancer Drug Resistance Induced by Disruption of the Saccharomyces cerevisiae NPR2 Gene: a Novel Component Involved in Cisplatin- and Doxorubicin-Provoked Cell Kill

Determination of Doxorubicin and Doxorubicinol in Plasma of Cancer Patients by High-Performance Liquid Chromatography

RNA Expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: Correlation with chemotherapeutic response

Quantitation of Cremophor EL in Human Plasma Samples Using a Colorimetric Dye-Binding Microassay

Effect of ABCG2 genotype on the oral bioavailability of topotecan

Molecular profiling of platinum resistant ovarian cancer

Disposition of [G-(3)H]paclitaxel and cremophor EL in a patient with severely impaired renal function

Effect of ABCG2 genotype on the oral vioavailability of topotecan

Association of enzyme and transporter genotypes with the pharmacokinetics of imatinib

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