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Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation

European journal of cancer (1990), 2001-09, Vol.37 (13), p.1590-1598

2001

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Clinical Pharmacokinetics and Metabolism of Irinotecan (CPT-11)

Clinical cancer research, 2001-08, Vol.7 (8), p.2182-2194

2001

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Body-Surface Area–Based Dosing Does Not Increase Accuracy of Predicting Cisplatin Exposure

Journal of clinical oncology, 2001-09, Vol.19 (17), p.3733-3739

2001

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Molecular Mechanisms of Multidrug Resistance in Cancer Chemotherapy

Pathology, research and practice, 1996, Vol.192 (7), p.768-780

1996

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Lack of c-kit exon 11 activating mutations in c-KIT/CD117-positive SCLC tumour specimens

European journal of cancer (1990), 2003-04, Vol.39 (6), p.793-799

2003

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Multidrug resistance (mdr) genes in human cancer

British journal of cancer, 1991-05, Vol.63 (5), p.663-669

1991

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Pharmacokinetic modeling of paclitaxel encapsulation in Cremophor EL micelles

Cancer chemotherapy and pharmacology, 2001-04, Vol.47 (4), p.309-318

2001

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Irinotecan pharmacokinetics-pharmacodynamics: the clinical relevance of prolonged exposure to SN-38

British journal of cancer, 2002-07, Vol.87 (2), p.144-150

2002

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Disposition of docetaxel in the presence of P-glycoprotein inhibition by intravenous administration of R101933

European journal of cancer (1990), 2002-05, Vol.38 (8), p.1090-1099

2002

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Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump

Blood, 2004-11, Vol.104 (9), p.2940-2942

2004

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Irinotecan (CPT-11) metabolism and disposition in cancer patients

Clinical cancer research, 1998-11, Vol.4 (11), p.2747-2754

1998

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The prognostic significance of expression of the multidrug resistance-associated protein (MRP) in primary breast cancer

British journal of cancer, 1997-01, Vol.76 (4), p.486-493

1997

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Expression of the multidrug resistance-associated protein (MRP) gene in human cancers

Clinical cancer research, 1995-11, Vol.1 (11), p.1301-1310

1995

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Pharmacokinetic Resistance to Imatinib Mesylate: Role of the ABC Drug Pumps ABCG2 (BCRP) and ABCB1 (MDR1) in the Oral Bioavailability of Imatinib

Cell cycle (Georgetown, Tex.), 2004-12, Vol.3 (12), p.1502-1505

2004

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Modulation of multidrug-resistant multiple myeloma by cyclosporin

The Lancet (British edition), 1992-08, Vol.340 (8814), p.255-259

1992

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Clinical relevance of P-glycoprotein expression in haematological malignancies

Leukemia Research, 1994-04, Vol.18 (4), p.233-243

1994

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Disposition of Cremophor EL in humans limits the potential for modulation of the multidrug resistance phenotype in vivo

Clinical cancer research, 1998-08, Vol.4 (8), p.1937-1942

1998

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Expression of p53, Bcl-2 and Bax in cisplatin-induced apoptosis in testicular germ cell tumour cell lines

British journal of cancer, 1998-05, Vol.77 (10), p.1562-1567

1998

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Expression of mdr1 and mdr3 Multidrug-resistance Genes in Human Acute and Chronic Leukemias and Association With Stimulation of Drug Accumulation by Cyclosporine

JNCI : Journal of the National Cancer Institute, 1990-07, Vol.82 (13), p.1133-1140

1990

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Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps

Cancer biology & therapy, 2005-07, Vol.4 (7), p.747-752

2005

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A pharmacokinetic interaction study of docetaxel and cisplatin plus or minus 5-fluorouracil in the treatment of patients with recurrent or metastatic solid tumors

Cancer chemotherapy and pharmacology, 2006-11, Vol.58 (5), p.673-680

2006

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RNA Expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: Correlation with chemotherapeutic response

Clinical cancer research, 2003-02, Vol.9 (2), p.827-836

2003

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Effect of ABCG2 genotype on the oral bioavailability of topotecan

Cancer biology & therapy, 2005-06, Vol.4 (6), p.650-658

2005

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Molecular profiling of platinum resistant ovarian cancer

International journal of cancer, 2006-04, Vol.118 (8), p.1963-1971

2006

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Reduced cellular accumulation of topotecan: a novel mechanism of resistance in a human ovarian cancer cell line

British journal of cancer, 1998-05, Vol.77 (10), p.1645-1652

1998

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Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation

Clinical Pharmacokinetics and Metabolism of Irinotecan (CPT-11)

Body-Surface Area–Based Dosing Does Not Increase Accuracy of Predicting Cisplatin Exposure

Molecular Mechanisms of Multidrug Resistance in Cancer Chemotherapy

Lack of c-kit exon 11 activating mutations in c-KIT/CD117-positive SCLC tumour specimens

Multidrug resistance (mdr) genes in human cancer

Pharmacokinetic modeling of paclitaxel encapsulation in Cremophor EL micelles

Irinotecan pharmacokinetics-pharmacodynamics: the clinical relevance of prolonged exposure to SN-38

Disposition of docetaxel in the presence of P-glycoprotein inhibition by intravenous administration of R101933

Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump

Irinotecan (CPT-11) metabolism and disposition in cancer patients

The prognostic significance of expression of the multidrug resistance-associated protein (MRP) in primary breast cancer

Expression of the multidrug resistance-associated protein (MRP) gene in human cancers

Pharmacokinetic Resistance to Imatinib Mesylate: Role of the ABC Drug Pumps ABCG2 (BCRP) and ABCB1 (MDR1) in the Oral Bioavailability of Imatinib

Modulation of multidrug-resistant multiple myeloma by cyclosporin

Clinical relevance of P-glycoprotein expression in haematological malignancies

Disposition of Cremophor EL in humans limits the potential for modulation of the multidrug resistance phenotype in vivo

Expression of p53, Bcl-2 and Bax in cisplatin-induced apoptosis in testicular germ cell tumour cell lines

Expression of mdr1 and mdr3 Multidrug-resistance Genes in Human Acute and Chronic Leukemias and Association With Stimulation of Drug Accumulation by Cyclosporine

Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps

A pharmacokinetic interaction study of docetaxel and cisplatin plus or minus 5-fluorouracil in the treatment of patients with recurrent or metastatic solid tumors

RNA Expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: Correlation with chemotherapeutic response

Effect of ABCG2 genotype on the oral bioavailability of topotecan

Molecular profiling of platinum resistant ovarian cancer

Reduced cellular accumulation of topotecan: a novel mechanism of resistance in a human ovarian cancer cell line

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