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Renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for new anti-diabetic agent

Current topics in medicinal chemistry, 2010-03, Vol.10 (4), p.411-418

Nomura, Sumihiro

2010

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Synthesis and Biological Evaluation of Thiophene-C-glucosides as Sodium-Dependent Glucose Cotransporter 2 Inhibitors

Chemical and Pharmaceutical Bulletin, 2013/10/01, Vol.61(10), pp.1037-1043

2013

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Discovery of Canagliflozin, a Novel C-Glucoside with Thiophene Ring, as Sodium-Dependent Glucose Cotransporter 2 Inhibitor for the Treatment of Type 2 Diabetes Mellitus

Journal of medicinal chemistry, 2010-09, Vol.53 (17), p.6355-6360

2010

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Aryl-β-C-glucosidation using glucal boronate: application to the synthesis of tri-O-methylnorbergenin

Tetrahedron, 2012-07, Vol.68 (29), p.5744-5753

2012

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Functionalized aryl-β-C-glycoside synthesis by Barbier-type reaction using 2,4,6-triisopropylphenyllithium

Tetrahedron letters, 2015-02, Vol.56 (8), p.1007-1010

2015

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Practical Synthesis of (20S)-10-(3-Aminopropyloxy)-7-ethylcamptothecin, a Water-Soluble Analogue of Camptothecin

Chemistry, an Asian journal, 2013-03, Vol.8 (3), p.630-638

2013

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Exploration of Novel C-Glucoside Formation and Application for SGLT2 Inhibitors —Discovery of Canagliflozin as a SGLT2 Inhibitor

Yūki gōsei kagaku kyōkaishi, 2016-09, Vol.74 (9), p.877-884

2016

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Stereoselective synthesis of six- and seven-membered ether rings based on the ring expansion

Tetrahedron letters, 1996-01, Vol.37 (2), p.213-216

1996

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N-glucosides as human sodium-dependent glucose cotransporter 2 (hSGLT2) inhibitors

Bioorganic & medicinal chemistry letters, 2013-10, Vol.23 (20), p.5641-5645

2013

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Novel Indole‑N‑glucoside, TA-1887 As a Sodium Glucose Cotransporter 2 Inhibitor for Treatment of Type 2 Diabetes

ACS medicinal chemistry letters, 2014-01, Vol.5 (1), p.51-55

2014

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Aryl-I2-C-glucosidation using glucal boronate: application to the synthesis of tri-O-methylnorbergenin

Tetrahedron, 2012-07, Vol.68 (29), p.5744-5753

2012

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C-Glucosides with heteroaryl thiophene as novel sodium-dependent glucose cotransporter 2 inhibitors

Bioorganic & medicinal chemistry, 2013-09, Vol.21 (17), p.5561-5572

2013

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STEREOSELECTIVE SYNTHESIS OF THE S- AND Y-RING SYSTEMS OF MAITOTOXIN

Chemical and Pharmaceutical Bulletin, 1996/03/15, Vol.44(3), pp.627-629

1996

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逆転の発想から生まれた，SGLT2阻害薬カナグリフロジン

ファルマシア, 2014, Vol.50(6), pp.538-542

野村, 純宏

2014

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Synthesis and SAR of N-benzoyl-L-biphenylalanine derivatives: discovery of TR-14035, a dual alpha(4)beta(7)/alpha(4)beta(1) integrin antagonist

Bioorganic & medicinal chemistry, 2002-06, Vol.10 (6), p.2051

2002

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Synthesis and SAR of N-benzoyl-L-biphenylalanine derivatives: Discovery of TR-14035, a dual α4β7/α4β1 integrin antagonist

Bioorganic & medicinal chemistry, 2002, Vol.10 (6), p.2051-2066

2002

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Stereoselective synthesis of the C- and CD-ring systems of hemibrevetoxin B

Tetrahedron letters, 1996-01, Vol.37 (2), p.217-220

1996

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Synthesis of dl-vincadifformine, dl-eburcine and dl-3-epieburcine. Introduction of methoxycarbonyl function to c(3)-position of aspidosperma skeleton

Tetrahedron, 1985, Vol.41 (23), p.5495-5501

1985

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Synthesis and SAR of N-Benzoyl- l-Biphenylalanine Derivatives: Discovery of TR-14035, A Dual α 4β 7/α 4β 1 Integrin Antagonist

Bioorganic & medicinal chemistry, 2002, Vol.10 (6), p.2051-2066

2002

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Synthesi of Aminobenzo[b]pyrrolizinone and Aminobenzo[b]indolizinone Derivatives

Heterocycles, 1996, Vol.42 (1), p.251

1996

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Unusual rearrangement reaction of quebrachamine derivative catalyzed by cyanide anion

Heterocycles, 1986-08, Vol.24 (8), p.2239-2245

1986

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Colchicine transdermal tape based on polyurethane adhesive

Drug Delivery System, 1991/11/10, Vol.6(6), pp.461-464

1991

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Renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for new anti-diabetic agent

Synthesis and Biological Evaluation of Thiophene-C-glucosides as Sodium-Dependent Glucose Cotransporter 2 Inhibitors

Discovery of Canagliflozin, a Novel C-Glucoside with Thiophene Ring, as Sodium-Dependent Glucose Cotransporter 2 Inhibitor for the Treatment of Type 2 Diabetes Mellitus

Aryl-β-C-glucosidation using glucal boronate: application to the synthesis of tri-O-methylnorbergenin

Functionalized aryl-β-C-glycoside synthesis by Barbier-type reaction using 2,4,6-triisopropylphenyllithium

Practical Synthesis of (20S)-10-(3-Aminopropyloxy)-7-ethylcamptothecin, a Water-Soluble Analogue of Camptothecin

Exploration of Novel C-Glucoside Formation and Application for SGLT2 Inhibitors —Discovery of Canagliflozin as a SGLT2 Inhibitor

Stereoselective synthesis of six- and seven-membered ether rings based on the ring expansion

N-glucosides as human sodium-dependent glucose cotransporter 2 (hSGLT2) inhibitors

Novel Indole‑N‑glucoside, TA-1887 As a Sodium Glucose Cotransporter 2 Inhibitor for Treatment of Type 2 Diabetes

Aryl-I2-C-glucosidation using glucal boronate: application to the synthesis of tri-O-methylnorbergenin

C-Glucosides with heteroaryl thiophene as novel sodium-dependent glucose cotransporter 2 inhibitors

STEREOSELECTIVE SYNTHESIS OF THE S- AND Y-RING SYSTEMS OF MAITOTOXIN

逆転の発想から生まれた，SGLT2阻害薬カナグリフロジン

Synthesis and SAR of N-benzoyl-L-biphenylalanine derivatives: discovery of TR-14035, a dual alpha(4)beta(7)/alpha(4)beta(1) integrin antagonist

Synthesis and SAR of N-benzoyl-L-biphenylalanine derivatives: Discovery of TR-14035, a dual α4β7/α4β1 integrin antagonist

Stereoselective synthesis of the C- and CD-ring systems of hemibrevetoxin B

Synthesis of dl-vincadifformine, dl-eburcine and dl-3-epieburcine. Introduction of methoxycarbonyl function to c(3)-position of aspidosperma skeleton

Synthesis and SAR of N-Benzoyl- l-Biphenylalanine Derivatives: Discovery of TR-14035, A Dual α 4β 7/α 4β 1 Integrin Antagonist

Synthesi of Aminobenzo[b]pyrrolizinone and Aminobenzo[b]indolizinone Derivatives

Unusual rearrangement reaction of quebrachamine derivative catalyzed by cyanide anion

Colchicine transdermal tape based on polyurethane adhesive

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