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Mesenchymal Plasticity Regulated by Prrx1 Drives Aggressive Pancreatic Cancer Biology

Gastroenterology (New York, N.Y. 1943), 2021-01, Vol.160 (1), p.346-361.e24

2021

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CD133 initiates tumors, induces epithelial-mesenchymal transition and increases metastasis in pancreatic cancer

Oncotarget, 2015-04, Vol.6 (10), p.8313-8322

2015

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Inhibition of hypoxic response decreases stemness and reduces tumorigenic signaling due to impaired assembly of HIF1 transcription complex in pancreatic cancer

Scientific reports, 2017-08, Vol.7 (1), p.7872-11, Article 7872

2017

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GRP78‐mediated antioxidant response and ABC transporter activity confers chemoresistance to pancreatic cancer cells

Molecular oncology, 2018-09, Vol.12 (9), p.1498-1512

2018

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Microenvironment mediated alterations to metabolic pathways confer increased chemo-resistance in CD133+ tumor initiating cells

Oncotarget, 2016-08, Vol.7 (35), p.56324-56337

2016

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Inhibition of Sp1 prevents ER homeostasis and causes cell death by lysosomal membrane permeabilization in pancreatic cancer

Scientific reports, 2017-05, Vol.7 (1), p.1564-9, Article 1564

2017

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Microenvironment in determining chemo-resistance in pancreatic cancer: Neighborhood matters

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2017-01, Vol.17 (1), p.7-12

2017

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Erlotinib sensitizes hepatocellular cancer cells to tumor necrosis factor-related apoptosis inducing ligand (TRAIL) induced cell death

Journal of the American College of Surgeons, 2013-09, Vol.217 (3), p.S139-S139

2013

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Inhibition of NF-kappa B pathway leads to deregulation of epithelial–mesenchymal transition and neural invasion in pancreatic cancer

Laboratory investigation, 2016-12, Vol.96 (12), p.1268-1278

2016

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Metastasis and chemoresistance in CD133 expressing pancreatic cancer cells are dependent on their lipid raft integrity

Cancer letters, 2018-12, Vol.439, p.101-112

2018

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CD133+ Tumor Initiating Cells in a Syngenic Murine Model of Pancreatic Cancer Respond to Minnelide

Clinical cancer research, 2014-05, Vol.20 (9), p.2388-2399

2014

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NFκB-Mediated Invasiveness in CD133 + Pancreatic TICs Is Regulated by Autocrine and Paracrine Activation of IL1 Signaling

Molecular cancer research, 2018-01, Vol.16 (1), p.162-172

2018

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Minnelide effectively eliminates CD133(+) side population in pancreatic cancer

Molecular cancer, 2015-11, Vol.14 (9161), p.200, Article 200

2015

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Abstract 3551: Lipid raft integrity is essential for metastasis and chemoresistance properties of CD133+ cancer stem cells in pancreatic cancer

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.3551-3551

2018

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A Novel Immunocompetent Mouse Model of Pancreatic Cancer with Robust Stroma: a Valuable Tool for Preclinical Evaluation of New Therapies

Journal of gastrointestinal surgery, 2016-01, Vol.20 (1), p.53-65

2016

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NFkB-mediated Invasiveness in CD133+ Pancreatic TICs is Regulated by Autocrine and Paracrine Activation of IL-1 Signaling

Molecular cancer research, 2017-09, Vol.16 (1), p.162-172

2017

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Abstract A24: CD133 initiates tumors, induces epithelial-mesenchymal transition, and increases metastasis in pancreatic cancer

Cancer research (Chicago, Ill.), 2015-07, Vol.75 (13_Supplement), p.A24-A24

2015

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Abstract B46: Low mitochondrial activity of CD133+ population enables evasion of apoptosis leading to increased chemo-resistance in tumor initiating cells

Cancer research (Chicago, Ill.), 2015-07, Vol.75 (13_Supplement), p.B46-B46

2015

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Co-deleting Pten with Rb in retinal progenitor cells in mice results in fully penetrant bilateral retinoblastomas

Molecular cancer, 2015-04, Vol.14 (1), p.93-93, Article 93

2015

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Microenvironment Mediated Metabolic-Reprogramming Regulate Self-renewal and Chemo-resistance in CD133+ Tumor Initiating Cells

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2017-07, Vol.17 (3), p.S10-S10

2017

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CD133 activates IL-1 signaling to induce EMT and invasion in pancreatic cancer

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2015-06, Vol.15 (3), p.S41-S41

2015

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437 A Novel Immunocompetent Orthotopic Mouse Model of Pancreatic Cancer With Robust Stroma: A Unique Tool for Evaluation of Therapies

Gastroenterology (New York, N.Y. 1943), 2015-04, Vol.148 (4), p.S-1106-S-1106

2015

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Inhibition of hypoxia decreases stemness and tumorigenic signaling due to impaired transcription complex in PDAC

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2017-09, Vol.17 (4), p.S11-S11

2017

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72 - A Novel Predictive Organoid Culture System from Pancreatic Cancer Patients - Personalized Medicine in Realtime

Gastroenterology (New York, N.Y. 1943), 2017-04, Vol.152 (5), p.S18-S18

2017

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A Novel Predictive Organoid Culture System from Pancreatic Cancer Patients - Personalized Medicine in Realtime

Gastroenterology (New York, N.Y. 1943), 2017-04, Vol.152 (5), p.S18-S18

2017

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Mesenchymal Plasticity Regulated by Prrx1 Drives Aggressive Pancreatic Cancer Biology

CD133 initiates tumors, induces epithelial-mesenchymal transition and increases metastasis in pancreatic cancer

Inhibition of hypoxic response decreases stemness and reduces tumorigenic signaling due to impaired assembly of HIF1 transcription complex in pancreatic cancer

GRP78‐mediated antioxidant response and ABC transporter activity confers chemoresistance to pancreatic cancer cells

Microenvironment mediated alterations to metabolic pathways confer increased chemo-resistance in CD133+ tumor initiating cells

Inhibition of Sp1 prevents ER homeostasis and causes cell death by lysosomal membrane permeabilization in pancreatic cancer

Microenvironment in determining chemo-resistance in pancreatic cancer: Neighborhood matters

Erlotinib sensitizes hepatocellular cancer cells to tumor necrosis factor-related apoptosis inducing ligand (TRAIL) induced cell death

Inhibition of NF-kappa B pathway leads to deregulation of epithelial–mesenchymal transition and neural invasion in pancreatic cancer

Metastasis and chemoresistance in CD133 expressing pancreatic cancer cells are dependent on their lipid raft integrity

CD133+ Tumor Initiating Cells in a Syngenic Murine Model of Pancreatic Cancer Respond to Minnelide

NFκB-Mediated Invasiveness in CD133 + Pancreatic TICs Is Regulated by Autocrine and Paracrine Activation of IL1 Signaling

Minnelide effectively eliminates CD133(+) side population in pancreatic cancer

Abstract 3551: Lipid raft integrity is essential for metastasis and chemoresistance properties of CD133+ cancer stem cells in pancreatic cancer

A Novel Immunocompetent Mouse Model of Pancreatic Cancer with Robust Stroma: a Valuable Tool for Preclinical Evaluation of New Therapies

NFkB-mediated Invasiveness in CD133+ Pancreatic TICs is Regulated by Autocrine and Paracrine Activation of IL-1 Signaling

Abstract A24: CD133 initiates tumors, induces epithelial-mesenchymal transition, and increases metastasis in pancreatic cancer

Abstract B46: Low mitochondrial activity of CD133+ population enables evasion of apoptosis leading to increased chemo-resistance in tumor initiating cells

Co-deleting Pten with Rb in retinal progenitor cells in mice results in fully penetrant bilateral retinoblastomas

Microenvironment Mediated Metabolic-Reprogramming Regulate Self-renewal and Chemo-resistance in CD133+ Tumor Initiating Cells

CD133 activates IL-1 signaling to induce EMT and invasion in pancreatic cancer

437 A Novel Immunocompetent Orthotopic Mouse Model of Pancreatic Cancer With Robust Stroma: A Unique Tool for Evaluation of Therapies

Inhibition of hypoxia decreases stemness and tumorigenic signaling due to impaired transcription complex in PDAC

72 - A Novel Predictive Organoid Culture System from Pancreatic Cancer Patients - Personalized Medicine in Realtime

A Novel Predictive Organoid Culture System from Pancreatic Cancer Patients - Personalized Medicine in Realtime

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