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A novel screening test to predict the developmental toxicity of drugs using human induced pluripotent stem cells

The Journal of Toxicological Sciences, 2020, Vol.45(4), pp.187-199

Aikawa, Nobuo

2020

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A Simple Protocol for the Myocardial Differentiation of Human iPS Cells

Biological and Pharmaceutical Bulletin, 2015/07/01, Vol.38(7), pp.1070-1075

2015

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The utility of human iPS cell-derived cardiomyocytes in predicting the clinical risk of drugs that display discordance of cardiotoxicity by species

Fundamental toxicological sciences, 2017, Vol.4 (3), p.127-136

Aikawa, Nobuo

2017

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Predicting clinical cardiotoxicity caused by trastuzumab and E-8010 using human cardiomyocytes

Fundamental toxicological sciences, 2017, Vol.4 (4), p.167-171

Aikawa, Nobuo

2017

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Detection of Thalidomide Embryotoxicity by In Vitro Embryotoxicity Testing Based on Human iPS Cells

Journal of Pharmacological Sciences, 2014/02/20, Vol.124(2), pp.201-207

2014

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Gender Differences in the Antidiarrheal Effect of Zaldaride Maleate in Rats

Biological and Pharmaceutical Bulletin, 2000/01/01, Vol.23(1), pp.33-36

2000

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Comparison of the Antidiarrheal Effects of Zaldaride Maleate and Its Optical Isomers in Rats

Biological and Pharmaceutical Bulletin, 2000/04/01, Vol.23(4), pp.402-405

2000

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The Effect of Zaldaride Maleate, an Antidiarrheal Compound, on Acetylcholine-Induced Intestinal Electrolyte Secretion

Biological and Pharmaceutical Bulletin, 2000/11/01, Vol.23(11), pp.1377-1378

2000

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Effects of KW-5617 (Zaldaride Maleate), a Potent and Selective Calmodulin Inhibitor, on Secretory Diarrhea and on Gastrointestinal Propulsion in Rats

The Japanese Journal of Pharmacology, 1998, Vol.76(2), pp.199-206

1998

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Effect of Zaldaride Maleate, an Antidiarrheal Compound, on Fecal Pellet Output Induced by Hyperpropulsion in Gastrointestine of Rats

The Japanese Journal of Pharmacology, 2000, Vol.82(4), pp.350-352

2000

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Effect of Zaldaride Maleate, an Antidiarrheal Compound, on Visceral Pain Reflex Induced by Small Intestinal Distention in Anesthetized Rats

Japanese Journal of Pharmacology, 1999, Vol.81 (4), p.381-387

1999

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Effect of Zaldaride Maleate, an Antidiarrheal Compound, on Fecal Pellet Output Induced by Hyperpropulsion in Gastrointestine of Rats

Japanese journal of pharmacology, 2000, Vol.82 (4), p.350-352

2000

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Effects of KW-5617, a calmodulin inhibitor, on various secretagogues-induced short-circuit current responses in rat colonic mucosa

Japanese Journal of Pharmacology, 1999, Vol.79 (suppl.1), p.207-207

1999

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Effects of KW-5617 (zaldaride maleate) on secretory diarrhea and gastrointestinal propulsion in rats

Japanese Journal of Pharmacology, 1998, Vol.76 (suppl.2), p.297-297

1998

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Effect of zaldaride maleate, an antidiarrheal compound, on intracellular cyclic nucleotide-mediated intestinal ion secretion in rats

European journal of pharmacology, 2000-04, Vol.394 (2), p.233-236

2000

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Effect of Zaldaride Maleate, an Antidiarrheal Compound, on Visceral Pain Reflex Induced by Small Intestinal Distention in Anesthetized Rats

The Japanese Journal of Pharmacology, 1999, Vol.81(4), pp.381-387

1999

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Antidiarrheal Effects of Zaldaride Maleate After Oral, Intravenous and Subcutaneous Administration to Rats

The Japanese Journal of Pharmacology, 1999, Vol.81(4), pp.397-400

1999

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Effect of Zaldaride Maleate, an Antidiarrheal Compound, on 16, 16-Dimethyl Prostaglandin E2-Induced Intestinal Ion Secretion in Rats

The Japanese Journal of Pharmacology, 2000, Vol.83(3), pp.269-272

2000

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Effect of Zaldaride Maleate, an Antidiarrheal Compound, on 16,16-Dimethyl Prostaglandin E2-Induced Intestinal Ion Secretion in Rats

Japanese journal of pharmacology, 2000, Vol.83 (3), p.269-272

2000

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Effects of Zaldaride Maleate, an Antidiarrheal Compound, on Intracellular Ca2+-Mediated Short-Circuit Current Response in the Rat Colonic Mucosa

Japanese journal of pharmacology, 2000, Vol.83 (1), p.86-88

2000

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Effects of Zaldaride Maleate, an Antidiarrheal Compound, on Intracellular Ca2+-Mediated Short-Circuit Current Response in the Rat Colonic Mucosa

The Japanese Journal of Pharmacology, 2000, Vol.83(1), pp.86-88

2000

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P-16 Embryonic stem cell test using human iPS cells-thalidomide embryotoxicity

Alternatives to Animal Testing and Experimentation, 2013-12, Vol.18 (suppl), p.179-179

2013

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Pharmacological properties of KW-3433, a new angiotensin II receptor antagonist

Japanese Journal of Pharmacology, 1994, Vol.64 (suppl.2), p.337-337

1994

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Effects of Zaldaride Maleate, an Antidiarrheal Compound, on Intracellular Ca^2+ -Mediated Short-Circuit Current Response in the Rat Colonic Mucosa

Japanese Journal of Pharmacology, 2000-05, Vol.83 (1), p.86-88

2000

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Effect of Zaldaride Maleate, an Antidiarrheal Compound, on 16,16-Dimethyl Prostaglandin E_2 -Induced Intestinal Ion Secretion in Rats

Japanese Journal of Pharmacology, 2000-07, Vol.83 (3), p.269-272

2000

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A novel screening test to predict the developmental toxicity of drugs using human induced pluripotent stem cells

A Simple Protocol for the Myocardial Differentiation of Human iPS Cells

The utility of human iPS cell-derived cardiomyocytes in predicting the clinical risk of drugs that display discordance of cardiotoxicity by species

Predicting clinical cardiotoxicity caused by trastuzumab and E-8010 using human cardiomyocytes

Detection of Thalidomide Embryotoxicity by In Vitro Embryotoxicity Testing Based on Human iPS Cells

Gender Differences in the Antidiarrheal Effect of Zaldaride Maleate in Rats

Comparison of the Antidiarrheal Effects of Zaldaride Maleate and Its Optical Isomers in Rats

The Effect of Zaldaride Maleate, an Antidiarrheal Compound, on Acetylcholine-Induced Intestinal Electrolyte Secretion

Effects of KW-5617 (Zaldaride Maleate), a Potent and Selective Calmodulin Inhibitor, on Secretory Diarrhea and on Gastrointestinal Propulsion in Rats

Effect of Zaldaride Maleate, an Antidiarrheal Compound, on Fecal Pellet Output Induced by Hyperpropulsion in Gastrointestine of Rats

Effect of Zaldaride Maleate, an Antidiarrheal Compound, on Visceral Pain Reflex Induced by Small Intestinal Distention in Anesthetized Rats

Effect of Zaldaride Maleate, an Antidiarrheal Compound, on Fecal Pellet Output Induced by Hyperpropulsion in Gastrointestine of Rats

Effects of KW-5617, a calmodulin inhibitor, on various secretagogues-induced short-circuit current responses in rat colonic mucosa

Effects of KW-5617 (zaldaride maleate) on secretory diarrhea and gastrointestinal propulsion in rats

Effect of zaldaride maleate, an antidiarrheal compound, on intracellular cyclic nucleotide-mediated intestinal ion secretion in rats

Effect of Zaldaride Maleate, an Antidiarrheal Compound, on Visceral Pain Reflex Induced by Small Intestinal Distention in Anesthetized Rats

Antidiarrheal Effects of Zaldaride Maleate After Oral, Intravenous and Subcutaneous Administration to Rats

Effect of Zaldaride Maleate, an Antidiarrheal Compound, on 16, 16-Dimethyl Prostaglandin E2-Induced Intestinal Ion Secretion in Rats

Effect of Zaldaride Maleate, an Antidiarrheal Compound, on 16,16-Dimethyl Prostaglandin E2-Induced Intestinal Ion Secretion in Rats

Effects of Zaldaride Maleate, an Antidiarrheal Compound, on Intracellular Ca2+-Mediated Short-Circuit Current Response in the Rat Colonic Mucosa

Effects of Zaldaride Maleate, an Antidiarrheal Compound, on Intracellular Ca2+-Mediated Short-Circuit Current Response in the Rat Colonic Mucosa

P-16 Embryonic stem cell test using human iPS cells-thalidomide embryotoxicity

Pharmacological properties of KW-3433, a new angiotensin II receptor antagonist

Effects of Zaldaride Maleate, an Antidiarrheal Compound, on Intracellular Ca^2+ -Mediated Short-Circuit Current Response in the Rat Colonic Mucosa

Effect of Zaldaride Maleate, an Antidiarrheal Compound, on 16,16-Dimethyl Prostaglandin E_2 -Induced Intestinal Ion Secretion in Rats

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