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Ligand-Bound Structures of the Dengue Virus Protease Reveal the Active Conformation

Journal of Virology, 2012-01, Vol.86 (1), p.438-446

2012

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A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis

Nature (London), 2017-06, Vol.546 (7658), p.376-380

2017

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Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design

Journal of medicinal chemistry, 2016-04, Vol.59 (8), p.3935-3952

2016

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Conformational Flexibility of the Dengue Virus RNA-Dependent RNA Polymerase Revealed by a Complex with an Inhibitor

Journal of Virology, 2013-05, Vol.87 (9), p.5291-5295

2013

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Bcl-xL and UVRAG Cause a Monomer-Dimer Switch in Beclin1

The Journal of biological chemistry, 2008-09, Vol.283 (38), p.26274-26282

2008

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Structure activity relationships of 4-hydroxy-2-pyridones: A novel class of antituberculosis agents

European journal of medicinal chemistry, 2015-12, Vol.106, p.144-156

2015

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The dengue virus NS5 protein as a target for drug discovery

Antiviral research, 2015-07, Vol.119, p.57-67

2015

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MLN51 stimulates the RNA-helicase activity of eIF4AIII

PloS one, 2007-03, Vol.2 (3), p.e303-e303

2007

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Structural Basis of Mycobacterial Inhibition by Cyclomarin A

The Journal of biological chemistry, 2013-10, Vol.288 (43), p.30883-30891

2013

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Structural biology of dengue virus enzymes: Towards rational design of therapeutics

Antiviral research, 2012-11, Vol.96 (2), p.115-126

2012

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Ten years of dengue drug discovery: Progress and prospects

Antiviral research, 2013-11, Vol.100 (2), p.500-519

2013

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The Role of GyrB in the DNA Cleavage-religation Reaction of DNA Gyrase: A Proposed Two Metal-ion Mechanism

Journal of molecular biology, 2002-04, Vol.318 (2), p.361-371

2002

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Key features of the interaction between Pcf11 CID and RNA polymerase II CTD

Nature structural & molecular biology, 2005-02, Vol.12 (2), p.144-151

2005

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Discovery of Potent Non-nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from Fragment Screening and Structure-Guided Design

Advances in experimental medicine and biology, 2018-01, Vol.1062, p.187-198

2018

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A cocrystal structure of dengue capsid protein in complex of inhibitor

Proceedings of the National Academy of Sciences - PNAS, 2020-07, Vol.117 (30), p.17992-18001

2020

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Two RNA Tunnel Inhibitors Bind in Highly Conserved Sites in Dengue Virus NS5 Polymerase: Structural and Functional Studies

Journal of virology, 2020-11, Vol.94 (24)

2020

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Strategies for development of dengue virus inhibitors

Antiviral research, 2010-03, Vol.85 (3), p.450-462

2010

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Direct inhibitors of InhA are active against Mycobacterium tuberculosis

Science translational medicine, 2015-01, Vol.7 (269), p.269ra3

2015

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NMR Analysis of a Novel Enzymatically Active Unlinked Dengue NS2B-NS3 Protease Complex

The Journal of biological chemistry, 2013-05, Vol.288 (18), p.12891-12900

2013

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Quinolone-DNA Interaction: Sequence-Dependent Binding to Single-Stranded DNA Reflects the Interaction within the Gyrase-DNA Complex

Antimicrobial Agents and Chemotherapy, 2003-03, Vol.47 (3), p.854-862

2003

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Crystal structure of dengue virus methyltransferase without S-adenosyl-L-methionine

Antiviral research, 2014-11, Vol.111, p.78-81

2014

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Generation and characterization of mouse monoclonal antibodies against NS4B protein of dengue virus

Virology (New York, N.Y.), 2014-02, Vol.450, p.250-257

2014

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Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor

Nucleic acids research, 2007-01, Vol.35 (1), p.87

2007

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Characterization of DLC1-SAM Equilibrium Unfolding at the Amino Acid Residue Level

Biochemistry (Easton), 2009-05, Vol.48 (19), p.4040-4049

2009

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RNA polymerase II CTD phosphopeptides compete with RNA for the interaction with Pcf11

RNA (Cambridge), 2006-04, Vol.12 (4), p.555-560

2006

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Ligand-Bound Structures of the Dengue Virus Protease Reveal the Active Conformation

A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis

Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design

Conformational Flexibility of the Dengue Virus RNA-Dependent RNA Polymerase Revealed by a Complex with an Inhibitor

Bcl-xL and UVRAG Cause a Monomer-Dimer Switch in Beclin1

Structure activity relationships of 4-hydroxy-2-pyridones: A novel class of antituberculosis agents

The dengue virus NS5 protein as a target for drug discovery

MLN51 stimulates the RNA-helicase activity of eIF4AIII

Structural Basis of Mycobacterial Inhibition by Cyclomarin A

Structural biology of dengue virus enzymes: Towards rational design of therapeutics

Ten years of dengue drug discovery: Progress and prospects

The Role of GyrB in the DNA Cleavage-religation Reaction of DNA Gyrase: A Proposed Two Metal-ion Mechanism

Key features of the interaction between Pcf11 CID and RNA polymerase II CTD

Discovery of Potent Non-nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from Fragment Screening and Structure-Guided Design

A cocrystal structure of dengue capsid protein in complex of inhibitor

Two RNA Tunnel Inhibitors Bind in Highly Conserved Sites in Dengue Virus NS5 Polymerase: Structural and Functional Studies

Strategies for development of dengue virus inhibitors

Direct inhibitors of InhA are active against Mycobacterium tuberculosis

NMR Analysis of a Novel Enzymatically Active Unlinked Dengue NS2B-NS3 Protease Complex

Quinolone-DNA Interaction: Sequence-Dependent Binding to Single-Stranded DNA Reflects the Interaction within the Gyrase-DNA Complex

Crystal structure of dengue virus methyltransferase without S-adenosyl-L-methionine

Generation and characterization of mouse monoclonal antibodies against NS4B protein of dengue virus

Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor

Characterization of DLC1-SAM Equilibrium Unfolding at the Amino Acid Residue Level

RNA polymerase II CTD phosphopeptides compete with RNA for the interaction with Pcf11

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