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Inhibition of Plasma Kallikrein by a Highly Specific Active Site Blocking Antibody

The Journal of biological chemistry, 2014-08, Vol.289 (34), p.23596-23608

2014

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Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis

Cancer research (Chicago, Ill.), 2009-02, Vol.69 (4), p.1517-1526

2009

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How can we discover developable antibody-based biotherapeutics?

Frontiers in molecular biosciences, 2023-08, Vol.10, p.1221626-1221626

2023

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An adapted consensus protein design strategy for identifying globally optimal biotherapeutics

mAbs, 2022, Vol.14 (1), p.2073632-2073632

2022

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Intrinsic physicochemical profile of marketed antibody-based biotherapeutics

Proceedings of the National Academy of Sciences - PNAS, 2021-09, Vol.118 (37)

2021

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A Bispecific DLL3/CD3 IgG-Like T-Cell Engaging Antibody Induces Antitumor Responses in Small Cell Lung Cancer

Clinical cancer research, 2020-10, Vol.26 (19), p.5258-5268

2020

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Drugs derived from phage display: From candidate identification to clinical practice

mAbs, 2014-01, Vol.6 (1), p.73-85

2014

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Specific inhibition of tissue kallikrein 1 with a human monoclonal antibody reveals a potential role in airway diseases

Biochemical journal, 2009-09, Vol.422 (2), p.383-392

2009

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Choices of capture chromatography technology in antibody manufacturing processes

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017-11, Vol.1068-1069, p.136-148

2017

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Selective Inhibition of Membrane Type 1 Matrix Metalloproteinase Abrogates Progression of Experimental Inflammatory Arthritis: Synergy With Tumor Necrosis Factor Blockade

Arthritis & rheumatology (Hoboken, N.J.), 2016-02, Vol.68 (2), p.521-531

2016

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The distinctive separation attributes of mixed-mode resins and their application in monoclonal antibody downstream purification process

Journal of Chromatography A, 2010-01, Vol.1217 (2), p.216-224

2010

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Fully human monoclonal antibody inhibitors of the neonatal fc receptor reduce circulating IgG in non-human primates

Frontiers in immunology, 2015-04, Vol.6, p.176-176

2015

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Combinatorial Protein Engineering by Incremental Truncation

Proceedings of the National Academy of Sciences - PNAS, 1999-03, Vol.96 (7), p.3562-3567

1999

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Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody

The Journal of biological chemistry, 2017-10, Vol.292 (42), p.17449-17460

2017

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Fully human monoclonal antibody inhibitors of the neonatal Fc receptor (FcRn) reduce circulating IgG in nonhuman primates

Frontiers in immunology, 2015-04, Vol.6

2015

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Rapid kinetic-based screening of human Fab fragments

Journal of immunological methods, 2006-03, Vol.310 (1), p.126-135

2006

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In silico enzyme screening identifies an SDR ketoreductase from Thermus caliditerrae as an attractive biocatalyst and promising candidate for protein engineering

Frontiers in Chemical Biology, 2024-07, Vol.3

2024

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A homogeneous fluorescence anisotropy assay for measuring transglutaminase 2 activity

Analytical biochemistry, 2013-05, Vol.436 (1), p.13-15

2013

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High-throughput affinity ranking of antibodies using surface plasmon resonance microarrays

Analytical biochemistry, 2006-04, Vol.351 (2), p.241-253

2006

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Evaluation of protein engineering and process optimization approaches to enhance antibody drug manufacturability

Biotechnology and bioengineering, 2011-11, Vol.108 (11), p.2634-2644

2011

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Rational Design of a Scytalone Dehydratase-Like Enzyme Using a Structurally Homologous Protein Scaffold

Proceedings of the National Academy of Sciences - PNAS, 1999-03, Vol.96 (7), p.3568-3571

1999

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Hybrid enzymes: manipulating enzyme design

Trends in biotechnology (Regular ed.), 1998-06, Vol.16 (6), p.258-264

1998

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Phage display as a tool for protease ligand discovery

Current pharmaceutical biotechnology, 2002-03, Vol.3 (1), p.1-12

Nixon, Andrew E

2002

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Incremental truncation as a strategy in the engineering of novel biocatalysts

Bioorganic & medicinal chemistry, 1999-10, Vol.7 (10), p.2139-2144

1999

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Inhibition of Plasma Kallikrein by a Highly Specific Active Site Blocking Antibody

Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis

How can we discover developable antibody-based biotherapeutics?

An adapted consensus protein design strategy for identifying globally optimal biotherapeutics

Intrinsic physicochemical profile of marketed antibody-based biotherapeutics

A Bispecific DLL3/CD3 IgG-Like T-Cell Engaging Antibody Induces Antitumor Responses in Small Cell Lung Cancer

Drugs derived from phage display: From candidate identification to clinical practice

Specific inhibition of tissue kallikrein 1 with a human monoclonal antibody reveals a potential role in airway diseases

Choices of capture chromatography technology in antibody manufacturing processes

Selective Inhibition of Membrane Type 1 Matrix Metalloproteinase Abrogates Progression of Experimental Inflammatory Arthritis: Synergy With Tumor Necrosis Factor Blockade

The distinctive separation attributes of mixed-mode resins and their application in monoclonal antibody downstream purification process

Fully human monoclonal antibody inhibitors of the neonatal fc receptor reduce circulating IgG in non-human primates

Combinatorial Protein Engineering by Incremental Truncation

Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody

Fully human monoclonal antibody inhibitors of the neonatal Fc receptor (FcRn) reduce circulating IgG in nonhuman primates

Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity

Rapid kinetic-based screening of human Fab fragments

In silico enzyme screening identifies an SDR ketoreductase from Thermus caliditerrae as an attractive biocatalyst and promising candidate for protein engineering

A homogeneous fluorescence anisotropy assay for measuring transglutaminase 2 activity

High-throughput affinity ranking of antibodies using surface plasmon resonance microarrays

Evaluation of protein engineering and process optimization approaches to enhance antibody drug manufacturability

Rational Design of a Scytalone Dehydratase-Like Enzyme Using a Structurally Homologous Protein Scaffold

Hybrid enzymes: manipulating enzyme design

Phage display as a tool for protease ligand discovery

Incremental truncation as a strategy in the engineering of novel biocatalysts

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