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Regioselective hydroxylation of steroid hormones by human cytochromes P450

Drug metabolism reviews, 2015-05, Vol.47 (2), p.89-110

2015

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Drug interactions between nine antifungal agents and drugs metabolized by human cytochromes P450

Current drug metabolism, 2014-01, Vol.15 (7), p.651-679

2014

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Effect of Antifungal Drugs on Cytochrome P450 (CYP) 2C9, CYP2C19, and CYP3A4 Activities in Human Liver Microsomes

Biological and Pharmaceutical Bulletin, 2005, Vol.28(9), pp.1805-1808

2005

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Comparison of the Stimulatory and Inhibitory Effects of Steroid Hormones and α-Naphthoflavone on Steroid Hormone Hydroxylation Catalyzed by Human Cytochrome P450 3A Subfamilies

Biological and Pharmaceutical Bulletin, 2021/04/01, Vol.44(4), pp.579-584

2021

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ヒト薬物代謝酵素シトクロムP450（CYP）2D6及びCYP3Aサブファミリーの代謝反応及び内在性ステロイドホルモンなどによる相互作用

YAKUGAKU ZASSHI, 2024/02/01, Vol.144(2), pp.197-202

丹羽, 俊朗

2024

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Role of amino acids at positions 34, 296, and 486 of cytochrome P450 2D6 in the stimulatory and inhibitory effects of psychotropic agents on dopamine formation from p-tyramine

Xenobiotica, 2021-11, Vol.51 (11), p.1229-1235

2021

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Inhibitory and Stimulatory Effects of Selective Serotonin Reuptake Inhibitors on Cytochrome P450 2D6-mediated Dopamine Formation from p-Tyramine

Journal of pharmacy & pharmaceutical sciences, 2019, Vol.22, p.585-592

2019

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Comparison of steroid hormone hydroxylation mediated by cytochrome P450 3A subfamilies

Archives of biochemistry and biophysics, 2020-03, Vol.682, p.108283-108283, Article 108283

2020

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Effect of genetic polymorphism on the inhibition of dopamine formation from p-tyramine catalyzed by brain cytochrome P450 2D6

Archives of biochemistry and biophysics, 2017-04, Vol.620, p.23-27

2017

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Effect of Human Cytochrome P450 2D6 Polymorphism on Progesterone Hydroxylation

European journal of drug metabolism and pharmacokinetics, 2022-09, Vol.47 (5), p.741-747

2022

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Comparison of the Stimulatory and Inhibitory Effects of Steroid Hormones and α-Naphthoflavone on Steroid Hormone Hydroxylation Catalyzed by Human Cytochrome P450 3A Subfamilies

Biological and Pharmaceutical Bulletin, 2021-04, Vol.44 (4), p.579-584

2021

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Substrate Specificity of Human Cytochrome P450 (CYP) 2C Subfamily and Effect of Azole Antifungal Agents on CYP2C8

Journal of pharmacy & pharmaceutical sciences, 2016-11, Vol.19 (4), p.423

2016

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Comparison of Steroid Hormone Hydroxylations by and Docking to Human Cytochromes P450 3A4 and 3A5

Journal of pharmacy & pharmaceutical sciences, 2019, Vol.22, p.332-339

2019

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Effect of penicillin-based antibiotics, amoxicillin, ampicillin, and piperacillin, on drug-metabolizing activities of human hepatic cytochromes P450

The Journal of Toxicological Sciences, 2016/02/01, Vol.41(1), pp.143-146

2016

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Relative contribution of rat CYP isoforms responsible for stereoselective metabolism of carvedilol

The Journal of Toxicological Sciences, 2018, Vol.43(1), pp.59-63

2018

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Metabolic Activities Catalyzed by Human Cytochrome P450 (CYP) 2D6 and CYP3A Subfamily Members and Effect of Various Compounds, Including Endogenous Steroid Hormones, on These Activities

Yakugaku zasshi, 2024-02, Vol.144 (2), p.197-202, Article 23-00174

Niwa, Toshiro

2024

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Effect of Cytochrome P450 (CYP) 2D6 Genetic Polymorphism on the Inhibitory Action of Antidepressants on CYP2D6-Mediated Dopamine Formation from p-Tyramine

Journal of pharmacy & pharmaceutical sciences, 2018-03, Vol.21 (1), p.135-142

2018

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Metabolic Activities Catalyzed by Human Cytochrome P450 (CYP) 2D6 and CYP3A Subfamily Members and Effect of Various Compounds, Including Endogenous Steroid Hormones, on These Activities

YAKUGAKU ZASSHI, 2024/02/01, Vol.144(2), pp.197-202

Niwa, Toshiro

2024

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Comparison of cytochrome P450 2C subfamily members in terms of drug oxidation rates and substrate inhibition

Current drug metabolism, 2012-10, Vol.13 (8), p.1145-1159

2012

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Prediction of Hepatic Clearance of Stereoselective Metabolism of Carvedilol in Liver Microsomes and Hepatocytes of Sprague-Dawley and Cytochrome P450 2D-Deficient Dark Agouti Rats

Journal of pharmacy & pharmaceutical sciences, 2019, Vol.22, p.72-84

2019

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Comparison of kinetic parameters for drug oxidation rates and substrate inhibition potential mediated by cytochrome P450 3A4 and 3A5

Current drug metabolism, 2008-01, Vol.9 (1), p.20-33

2008

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Application of substrate depletion assay to evaluation of CYP isoforms responsible for stereoselective metabolism of carvedilol

Drug metabolism and pharmacokinetics, 2016-12, Vol.31 (6), p.425-432

2016

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Comparison of cytochrome P450 2D6 and variants in terms of drug oxidation rates and substrate inhibition

Current drug metabolism, 2011-06, Vol.12 (5), p.412-435

2011

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Comparison of catalytic and inhibitory properties in human drug-metabolizing cytochrome P450 3A4 and 3A5 for various compounds including endogenous steroid hormones and azole antifungals by molecular docking simulation

Drug metabolism and pharmacokinetics, 2017-01, Vol.32 (1), p.S38-S38

2017

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Inhibition of Human Steroidogenic Cytochrome P450 c17 by 21-Hydroxypregnenolone and Related Steroid Hormones

Biological and Pharmaceutical Bulletin, 2012/09/01, Vol.35(9), pp.1594-1597

2012

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Regioselective hydroxylation of steroid hormones by human cytochromes P450

Drug interactions between nine antifungal agents and drugs metabolized by human cytochromes P450

Effect of Antifungal Drugs on Cytochrome P450 (CYP) 2C9, CYP2C19, and CYP3A4 Activities in Human Liver Microsomes

Comparison of the Stimulatory and Inhibitory Effects of Steroid Hormones and α-Naphthoflavone on Steroid Hormone Hydroxylation Catalyzed by Human Cytochrome P450 3A Subfamilies

ヒト薬物代謝酵素シトクロムP450（CYP）2D6及びCYP3Aサブファミリーの代謝反応及び内在性ステロイドホルモンなどによる相互作用

Role of amino acids at positions 34, 296, and 486 of cytochrome P450 2D6 in the stimulatory and inhibitory effects of psychotropic agents on dopamine formation from p-tyramine

Inhibitory and Stimulatory Effects of Selective Serotonin Reuptake Inhibitors on Cytochrome P450 2D6-mediated Dopamine Formation from p-Tyramine

Comparison of steroid hormone hydroxylation mediated by cytochrome P450 3A subfamilies

Effect of genetic polymorphism on the inhibition of dopamine formation from p-tyramine catalyzed by brain cytochrome P450 2D6

Effect of Human Cytochrome P450 2D6 Polymorphism on Progesterone Hydroxylation

Comparison of the Stimulatory and Inhibitory Effects of Steroid Hormones and α-Naphthoflavone on Steroid Hormone Hydroxylation Catalyzed by Human Cytochrome P450 3A Subfamilies

Substrate Specificity of Human Cytochrome P450 (CYP) 2C Subfamily and Effect of Azole Antifungal Agents on CYP2C8

Comparison of Steroid Hormone Hydroxylations by and Docking to Human Cytochromes P450 3A4 and 3A5

Effect of penicillin-based antibiotics, amoxicillin, ampicillin, and piperacillin, on drug-metabolizing activities of human hepatic cytochromes P450

Relative contribution of rat CYP isoforms responsible for stereoselective metabolism of carvedilol

Metabolic Activities Catalyzed by Human Cytochrome P450 (CYP) 2D6 and CYP3A Subfamily Members and Effect of Various Compounds, Including Endogenous Steroid Hormones, on These Activities

Effect of Cytochrome P450 (CYP) 2D6 Genetic Polymorphism on the Inhibitory Action of Antidepressants on CYP2D6-Mediated Dopamine Formation from p-Tyramine

Metabolic Activities Catalyzed by Human Cytochrome P450 (CYP) 2D6 and CYP3A Subfamily Members and Effect of Various Compounds, Including Endogenous Steroid Hormones, on These Activities

Comparison of cytochrome P450 2C subfamily members in terms of drug oxidation rates and substrate inhibition

Prediction of Hepatic Clearance of Stereoselective Metabolism of Carvedilol in Liver Microsomes and Hepatocytes of Sprague-Dawley and Cytochrome P450 2D-Deficient Dark Agouti Rats

Comparison of kinetic parameters for drug oxidation rates and substrate inhibition potential mediated by cytochrome P450 3A4 and 3A5

Application of substrate depletion assay to evaluation of CYP isoforms responsible for stereoselective metabolism of carvedilol

Comparison of cytochrome P450 2D6 and variants in terms of drug oxidation rates and substrate inhibition

Comparison of catalytic and inhibitory properties in human drug-metabolizing cytochrome P450 3A4 and 3A5 for various compounds including endogenous steroid hormones and azole antifungals by molecular docking simulation

Inhibition of Human Steroidogenic Cytochrome P450 c17 by 21-Hydroxypregnenolone and Related Steroid Hormones

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