UB Paderborn / Katalog / Suche / in CDI

Quenching protein dynamics interferes with HIV capsid maturation

Nature communications, 2017-11, Vol.8 (1), p.1779-12, Article 1779

2017

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Resistance to Second-Generation HIV-1 Maturation Inhibitors

Journal of virology, 2019-03, Vol.93 (6)

2019

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The prototype HIV-1 maturation inhibitor, bevirimat, binds to the CA-SP1 cleavage site in immature Gag particles

Retrovirology, 2011-12, Vol.8 (1), p.101-101, Article 101

2011

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Alkyl Amine Bevirimat Derivatives Are Potent and Broadly Active HIV-1 Maturation Inhibitors

Antimicrobial agents and chemotherapy, 2016-01, Vol.60 (1), p.190-197

2016

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Identification of potent maturation inhibitors against HIV-1 clade C

Scientific reports, 2016-06, Vol.6 (1), p.27403-27403, Article 27403

2016

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Anti-AIDS Agents. 78. Design, Synthesis, Metabolic Stability Assessment, and Antiviral Evaluation of Novel Betulinic Acid Derivatives as Potent Anti-Human Immunodeficiency Virus (HIV) Agents

Journal of medicinal chemistry, 2009-05, Vol.52 (10), p.3248-3258

2009

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Anti-AIDS agents 73: Structure–activity relationship study and asymmetric synthesis of 3- O-monomethylsuccinyl-betulinic acid derivatives

Bioorganic & medicinal chemistry letters, 2007-12, Vol.17 (23), p.6553-6557

2007

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Antiviral efficacy of VP14637 against respiratory syncytial virus in vitro and in cotton rats following delivery by small droplet aerosol

Antiviral research, 2005-10, Vol.68 (1), p.18-26

2005

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Regiospecific Synthesis of 3-Substituted 5-Alkylisoxazoles from Oxime Dianions and N-Methoxy-N-Methylalkylamides

Journal of organic chemistry, 1994-09, Vol.59 (19), p.5828-5832

1994

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Antipicornavirus activity of tetrazole analogs related to disoxaril

Journal of medicinal chemistry, 1993-10, Vol.36 (22), p.3240-3250

1993

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Parallel synthesis of 1,2,4-oxadiazoles using CDI activation

Bioorganic & medicinal chemistry letters, 1999-01, Vol.9 (2), p.209-212

1999

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Oxadiazoles as Ester Bioisosteric Replacements in Compounds Related to Disoxaril. Antirhinovirus Activity

Journal of medicinal chemistry, 1994-07, Vol.37 (15), p.2421-2436

1994

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Picornavirus Inhibitors: Trifluoromethyl Substitution Provides a Global Protective Effect against Hepatic Metabolism

Journal of medicinal chemistry, 1995-04, Vol.38 (8), p.1355-1371

1995

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Ingenane synthetic studies. An expedient approach to highly oxygenated ABC subunits of ingenol via reductive dialkylative annulation and .alpha.,.beta.-epoxy ketone photoisomerization

Journal of the American Chemical Society, 1984-03, Vol.106 (5), p.1446-1454

1984

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An excursion into the synthesis of potential angiotensin converting enzyme inhibitors

Journal of organic chemistry, 1982-10, Vol.47 (21), p.4029-4032

1982

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N-[(Carbobenzyl)oxy]-.DELTA.E-phenylalanine ethyl ester

Journal of organic chemistry, 1981-06, Vol.46 (13), p.2667-2671

1981

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3-Pyridines as replacements for an isoxazole ring: The antirhinoviral activity of pyridine analogues related to disoxaril

Bioorganic & medicinal chemistry letters, 1995-05, Vol.5 (9), p.985-990

1995

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Chemoselective ethylene acetalization of α, β-unsaturated vis-à-vis saturated carbonyl groups

Tetrahedron letters, 1984, Vol.25 (29), p.3047-3050

1984

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E/ Z-Configurational assignment of dehydropeptides: Differential noe enhancement between the vinyl and amide protons of an α,β-dehydro amino acid derivative

Tetrahedron letters, 1982, Vol.23 (32), p.3235-3236

1982

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From Natural Product to Clinical Trials: Bevirimat, a Plant-Derived Anti-AIDS Drug

Natural Product Chemistry for Drug Discovery, 2010, p.1-1

2010

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Importance of the stereo-orientation of aromatic groups in enkephalins to opiate receptor recognition

Biochemical and biophysical research communications, 1984-06, Vol.121 (3), p.966-972

1984

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Chapter 13 - From Natural Product to Clinical Trials: Bevirimat, a Plant-Derived Anti-AIDS Drug

Natural Product Chemistry for Drug Discovery, 2009, p.374-391

2009

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ChemInform Abstract: Parallel Synthesis of 1,2,4-Oxadiazoles Using CDI Activation

ChemInform, 1999-05, Vol.30 (19), p.no-no

1999

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Synthesis and receptor binding affinity of both E-and Z-dehydro-phenylaline4 enkephalins

International Journal of Peptide and Protein Research, 1986-05, Vol.27 (5), p.522-529

1986

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Synthesis and receptor binding affinity of both E‐and Z‐dehydro‐phenylaline 4 enkephalins

International journal of peptide and protein research, 1986-05, Vol.27 (5), p.522-529

1986

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Quenching protein dynamics interferes with HIV capsid maturation

Resistance to Second-Generation HIV-1 Maturation Inhibitors

The prototype HIV-1 maturation inhibitor, bevirimat, binds to the CA-SP1 cleavage site in immature Gag particles

Alkyl Amine Bevirimat Derivatives Are Potent and Broadly Active HIV-1 Maturation Inhibitors

Identification of potent maturation inhibitors against HIV-1 clade C

Anti-AIDS Agents. 78. Design, Synthesis, Metabolic Stability Assessment, and Antiviral Evaluation of Novel Betulinic Acid Derivatives as Potent Anti-Human Immunodeficiency Virus (HIV) Agents

Anti-AIDS agents 73: Structure–activity relationship study and asymmetric synthesis of 3- O-monomethylsuccinyl-betulinic acid derivatives

Antiviral efficacy of VP14637 against respiratory syncytial virus in vitro and in cotton rats following delivery by small droplet aerosol

Regiospecific Synthesis of 3-Substituted 5-Alkylisoxazoles from Oxime Dianions and N-Methoxy-N-Methylalkylamides

Antipicornavirus activity of tetrazole analogs related to disoxaril

Parallel synthesis of 1,2,4-oxadiazoles using CDI activation

Oxadiazoles as Ester Bioisosteric Replacements in Compounds Related to Disoxaril. Antirhinovirus Activity

Picornavirus Inhibitors: Trifluoromethyl Substitution Provides a Global Protective Effect against Hepatic Metabolism

Ingenane synthetic studies. An expedient approach to highly oxygenated ABC subunits of ingenol via reductive dialkylative annulation and .alpha.,.beta.-epoxy ketone photoisomerization

An excursion into the synthesis of potential angiotensin converting enzyme inhibitors

N-[(Carbobenzyl)oxy]-.DELTA.E-phenylalanine ethyl ester

3-Pyridines as replacements for an isoxazole ring: The antirhinoviral activity of pyridine analogues related to disoxaril

Chemoselective ethylene acetalization of α, β-unsaturated vis-à-vis saturated carbonyl groups

E/ Z-Configurational assignment of dehydropeptides: Differential noe enhancement between the vinyl and amide protons of an α,β-dehydro amino acid derivative

From Natural Product to Clinical Trials: Bevirimat, a Plant-Derived Anti-AIDS Drug

Importance of the stereo-orientation of aromatic groups in enkephalins to opiate receptor recognition

Chapter 13 - From Natural Product to Clinical Trials: Bevirimat, a Plant-Derived Anti-AIDS Drug

ChemInform Abstract: Parallel Synthesis of 1,2,4-Oxadiazoles Using CDI Activation

Synthesis and receptor binding affinity of both E-and Z-dehydro-phenylaline4 enkephalins

Synthesis and receptor binding affinity of both E‐and Z‐dehydro‐phenylaline 4 enkephalins

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