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Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells

Nature communications, 2017-07, Vol.8 (1), p.16114-16114, Article 16114

2017

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Deletion of the autism-related gene Chd8 alters activity-dependent transcriptional responses in mouse postmitotic neurons

Communications biology, 2023-06, Vol.6 (1), p.593-593, Article 593

2023

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The FBXL5-IRP2 Axis Is Integral to Control of Iron Metabolism In Vivo

Cell metabolism, 2011-09, Vol.14 (3), p.339-351

2011

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Oligodendrocyte dysfunction due to Chd8 mutation gives rise to behavioral deficits in mice

Human molecular genetics, 2020-05, Vol.29 (8), p.1274-1291

2020

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The autism-associated protein CHD8 is required for cerebellar development and motor function

Cell reports (Cambridge), 2021-04, Vol.35 (1), p.108932, Article 108932

2021

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Histone H1 Recruitment by CHD8 Is Essential for Suppression of the Wnt–β-Catenin Signaling Pathway

Molecular and Cellular Biology, 2012-01, Vol.32 (2), p.501-512

2012

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The autism-related protein CHD8 contributes to the stemness and differentiation of mouse hematopoietic stem cells

Cell reports (Cambridge), 2021-02, Vol.34 (5), p.108688-108688, Article 108688

2021

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FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells

Molecular and cellular biology, 2017-04, Vol.37 (8)

2017

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HERC2 Targets the Iron Regulator FBXL5 for Degradation and Modulates Iron Metabolism

The Journal of biological chemistry, 2014-06, Vol.289 (23), p.16430-16441

2014

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Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autism

BMC neuroscience, 2021-05, Vol.22 (1), p.32-32, Article 32

2021

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Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

The EMBO journal, 2004-05, Vol.23 (10), p.2116-2125

2004

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Skp2 contributes to cell cycle progression in trophoblast stem cells and to placental development

Genes to cells : devoted to molecular & cellular mechanisms, 2020-06, Vol.25 (6), p.427-438

2020

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FBXL12‐Mediated Degradation of ALDH3 is Essential for Trophoblast Differentiation During Placental Development

Stem cells (Dayton, Ohio), 2015-11, Vol.33 (11), p.3327-3340

2015

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MDM2 Mediates Nonproteolytic Polyubiquitylation of the DEAD-Box RNA Helicase DDX24

Molecular and cellular biology, 2014-09, Vol.34 (17), p.3321-3340

2014

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Mouse Fbw7/Sel-10/Cdc4 Is Required for Notch Degradation during Vascular Development

The Journal of biological chemistry, 2004-03, Vol.279 (10), p.9417-9423

2004

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Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brain

Molecular brain, 2020-11, Vol.13 (1), p.160-160, Article 160

2020

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Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin‐dependent degradation

Cancer science, 2006-08, Vol.97 (8), p.729-736

2006

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A fluorescent sensor for real-time measurement of extracellular oxytocin dynamics in the brain

Nature methods, 2022-10, Vol.19 (10), p.1286-1294

2022

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Macrophage-derived exosomes induce inflammatory factors in endothelial cells under hypertensive conditions

Hypertension research, 2017-04, Vol.40 (4), p.353-360

2017

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Fbxw8 Is Essential for Cul1-Cul7 Complex Formation and for Placental Development

Molecular and Cellular Biology, 2006-08, Vol.26 (16), p.6157-6169

2006

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Classification of multiple emotional states from facial expressions in head-fixed mice using a deep learning-based image analysis

PloS one, 2023-07, Vol.18 (7), p.e0288930-e0288930

2023

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CHD8 haploinsufficiency results in autistic-like phenotypes in mice

Nature (London), 2016-09, Vol.537 (7622), p.675-679

2016

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Chromatin remodeler CHD8 is required for spermatogonial proliferation and early meiotic progression

Nucleic acids research, 2024-04, Vol.52 (6), p.2995-3010

2024

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Early Embryonic Death in Mice Lacking the β-Catenin-Binding Protein Duplin

Molecular and Cellular Biology, 2004-10, Vol.24 (19), p.8386-8394

2004

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The complex etiology of autism spectrum disorder due to missense mutations of CHD8

Molecular psychiatry, 2024-07, Vol.29 (7), p.2145-2160

2024

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Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells

Deletion of the autism-related gene Chd8 alters activity-dependent transcriptional responses in mouse postmitotic neurons

The FBXL5-IRP2 Axis Is Integral to Control of Iron Metabolism In Vivo

Oligodendrocyte dysfunction due to Chd8 mutation gives rise to behavioral deficits in mice

The autism-associated protein CHD8 is required for cerebellar development and motor function

Histone H1 Recruitment by CHD8 Is Essential for Suppression of the Wnt–β-Catenin Signaling Pathway

The autism-related protein CHD8 contributes to the stemness and differentiation of mouse hematopoietic stem cells

FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells

HERC2 Targets the Iron Regulator FBXL5 for Degradation and Modulates Iron Metabolism

Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autism

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

Skp2 contributes to cell cycle progression in trophoblast stem cells and to placental development

FBXL12‐Mediated Degradation of ALDH3 is Essential for Trophoblast Differentiation During Placental Development

MDM2 Mediates Nonproteolytic Polyubiquitylation of the DEAD-Box RNA Helicase DDX24

Mouse Fbw7/Sel-10/Cdc4 Is Required for Notch Degradation during Vascular Development

Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brain

Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin‐dependent degradation

A fluorescent sensor for real-time measurement of extracellular oxytocin dynamics in the brain

Macrophage-derived exosomes induce inflammatory factors in endothelial cells under hypertensive conditions

Fbxw8 Is Essential for Cul1-Cul7 Complex Formation and for Placental Development

Classification of multiple emotional states from facial expressions in head-fixed mice using a deep learning-based image analysis

CHD8 haploinsufficiency results in autistic-like phenotypes in mice

Chromatin remodeler CHD8 is required for spermatogonial proliferation and early meiotic progression

Early Embryonic Death in Mice Lacking the β-Catenin-Binding Protein Duplin

The complex etiology of autism spectrum disorder due to missense mutations of CHD8

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