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Interleukin-6 as a Therapeutic Target in Candidate Inflammatory Diseases

Clinical pharmacology and therapeutics, 2010-04, Vol.87 (4), p.483-487

Nishimoto, N

2010

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Long-term safety and efficacy of tocilizumab, an anti-IL-6 receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis (the STREAM study): evidence of safety and efficacy in a 5-year extension study

Annals of the rheumatic diseases, 2009-10, Vol.68 (10), p.1580-1584

2009

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Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab

Annals of the rheumatic diseases, 2007-09, Vol.66 (9), p.1162-1167

2007

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Humanized antihuman IL-6 receptor antibody, tocilizumab

Handbook of experimental pharmacology, 2008 (181), p.151

2008

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Inhibition of IL-6 for the treatment of inflammatory diseases

Current opinion in pharmacology, 2004-08, Vol.4 (4), p.386-391

2004

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Blood identification and discrimination between human and nonhuman blood using portable Raman spectroscopy

International journal of legal medicine, 2017-03, Vol.131 (2), p.319-322

2017

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SAT0176 IL-6 Blockade with Tocilizumab Does Not Suppress CD4+T Cell Activation at 48 Weeks of The Treatment

Annals of the rheumatic diseases, 2016-06, Vol.75 (Suppl 2), p.731-731

2016

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Anti-interleukin 6 receptor antibody treatment in rheumatic disease

Annals of the rheumatic diseases, 2000-11, Vol.59 (suppl 1), p.i21-i27

2000

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Superovulatory response in Japanese Black cows receiving a single subcutaneous porcine follicle–stimulating hormone treatment or six intramuscular treatments over three days

Theriogenology, 2015-03, Vol.83 (4), p.466-473

2015

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Temperature dependent local atomic displacements in ammonia intercalated iron selenide superconductor

Scientific reports, 2016-06, Vol.6 (1), p.27646-27646, Article 27646

2016

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Therapeutic adenoviral gene transfer of a glycosyltransferase for prevention of peritoneal dissemination and metastasis of gastric cancer

Cancer gene therapy, 2014-10, Vol.21 (10), p.427-433

2014

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Laboratory and febrile features after joint surgery in patients with rheumatoid arthritis treated with tocilizumab

Annals of the rheumatic diseases, 2009-05, Vol.68 (5), p.654-657

2009

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AB0709 SERUM IL-12/23 AND IL-17 LEVELS IN PATIENTS WITH SPONDYLOARTHRITIS WERE NOT INFLUENCED BY TNF-BLOCKADE

Annals of the rheumatic diseases, 2020-06, Vol.79 (Suppl 1), p.1650-1650

2020

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Multicenter phase 2 trial of weekly 5-FU plus l-LV regimen as salvage line chemotherapy for oral fluorouracil-resistant advanced gastric cancer (HGCSG1502)

Annals of oncology, 2019-07, Vol.30, p.iv48-iv48

2019

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Interleukin 6: from bench to bedside

Nature clinical practice. Rheumatology, 2006-11, Vol.2 (11), p.619-626

2006

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Reduced-intensity vs myeloablative conditioning allogeneic hematopoietic SCT for patients aged over 45 years with ALL in remission: a study from the Adult ALL Working Group of the Japan Society for Hematopoietic Cell Transplantation (JSHCT)

Bone marrow transplantation (Basingstoke), 2013-11, Vol.48 (11), p.1389-1394

2013

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THU0014 Composition of Dendritic Cell and NK Cell-Related Network with Abnormally Expressed Glycosylation-Related Molecules in the Bone Marrow Cells from Patients with Rheumatoid Arthritis

Annals of the rheumatic diseases, 2015-06, Vol.74 (Suppl 2), p.197-198

2015

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Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo

Nature medicine, 2000-05, Vol.6 (5), p.583-588

2000

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Pro-inflammatory responses and oxidative stress induced by ZnO nanoparticles in vivo following intravenous injection

European review for medical and pharmacological sciences, 2015-12, Vol.19 (24), p.4920

2015

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Interleukin-6 in rheumatoid arthritis

Current opinion in rheumatology, 2006-05, Vol.18 (3), p.277-281

Nishimoto, Norihiro

2006

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Abnormal expression of the genes involved in cytokine networks and mitochondrial function in systemic juvenile idiopathic arthritis identified by DNA microarray analysis

Annals of the rheumatic diseases, 2009-02, Vol.68 (2), p.264-272

2009

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AB0049 Appearance of CD14+CD15+ Poplulation During the Differentiation from RA-IPS Cells into Monocytes

Annals of the rheumatic diseases, 2014-06, Vol.73 (Suppl 2), p.820-820

2014

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AB0100 Monocytes Differentiated from IPS Cells Derived from Rheumatoid Arthritis Patients Express More M-Scf-Receptor Together with Rank Than Those from Healthy Donors Resulting in the Accelerated Osteoclastgenesis

Annals of the rheumatic diseases, 2015-06, Vol.74 (Suppl 2), p.924-924

2015

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AB0486 Effect of Baseline Disease Duration on Development of Clinical Remission in the RA Patients Receiving Tocilizumab – Data from PMS with Tocilizumab in Biologics-Naïve RA Patients (First Bio) Study

Annals of the rheumatic diseases, 2015-06, Vol.74 (Suppl 2), p.1060-1060

2015

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SAT0211 Effectiveness and Safety of Tocilizumab in Biologics Naïve RA Patients – PMS for Investigating Success in Achieving Clinical and Functional Remission and Sustaining Efficacy with Tocilizumab in Biologics-Naïve RA Patients (First Bio) Study

Annals of the rheumatic diseases, 2015-06, Vol.74 (Suppl 2), p.733

2015

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Interleukin-6 as a Therapeutic Target in Candidate Inflammatory Diseases

Long-term safety and efficacy of tocilizumab, an anti-IL-6 receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis (the STREAM study): evidence of safety and efficacy in a 5-year extension study

Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab

Humanized antihuman IL-6 receptor antibody, tocilizumab

Inhibition of IL-6 for the treatment of inflammatory diseases

Blood identification and discrimination between human and nonhuman blood using portable Raman spectroscopy

SAT0176 IL-6 Blockade with Tocilizumab Does Not Suppress CD4+T Cell Activation at 48 Weeks of The Treatment

Anti-interleukin 6 receptor antibody treatment in rheumatic disease

Superovulatory response in Japanese Black cows receiving a single subcutaneous porcine follicle–stimulating hormone treatment or six intramuscular treatments over three days

Temperature dependent local atomic displacements in ammonia intercalated iron selenide superconductor

Therapeutic adenoviral gene transfer of a glycosyltransferase for prevention of peritoneal dissemination and metastasis of gastric cancer

Laboratory and febrile features after joint surgery in patients with rheumatoid arthritis treated with tocilizumab

AB0709 SERUM IL-12/23 AND IL-17 LEVELS IN PATIENTS WITH SPONDYLOARTHRITIS WERE NOT INFLUENCED BY TNF-BLOCKADE

Multicenter phase 2 trial of weekly 5-FU plus l-LV regimen as salvage line chemotherapy for oral fluorouracil-resistant advanced gastric cancer (HGCSG1502)

Interleukin 6: from bench to bedside

Reduced-intensity vs myeloablative conditioning allogeneic hematopoietic SCT for patients aged over 45 years with ALL in remission: a study from the Adult ALL Working Group of the Japan Society for Hematopoietic Cell Transplantation (JSHCT)

THU0014 Composition of Dendritic Cell and NK Cell-Related Network with Abnormally Expressed Glycosylation-Related Molecules in the Bone Marrow Cells from Patients with Rheumatoid Arthritis

Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo

Pro-inflammatory responses and oxidative stress induced by ZnO nanoparticles in vivo following intravenous injection

Interleukin-6 in rheumatoid arthritis

Abnormal expression of the genes involved in cytokine networks and mitochondrial function in systemic juvenile idiopathic arthritis identified by DNA microarray analysis

AB0049 Appearance of CD14+CD15+ Poplulation During the Differentiation from RA-IPS Cells into Monocytes

AB0100 Monocytes Differentiated from IPS Cells Derived from Rheumatoid Arthritis Patients Express More M-Scf-Receptor Together with Rank Than Those from Healthy Donors Resulting in the Accelerated Osteoclastgenesis

AB0486 Effect of Baseline Disease Duration on Development of Clinical Remission in the RA Patients Receiving Tocilizumab – Data from PMS with Tocilizumab in Biologics-Naïve RA Patients (First Bio) Study

SAT0211 Effectiveness and Safety of Tocilizumab in Biologics Naïve RA Patients – PMS for Investigating Success in Achieving Clinical and Functional Remission and Sustaining Efficacy with Tocilizumab in Biologics-Naïve RA Patients (First Bio) Study

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