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Immune Cell Gene Signatures for Profiling the Microenvironment of Solid Tumors

Cancer immunology research, 2018-11, Vol.6 (11), p.1388-1400

2018

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Multiplexed and reproducible high content screening of live and fixed cells using Dye Drop

Nature communications, 2022-11, Vol.13 (1), p.6918-18, Article 6918

2022

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Transcriptomics Analysis of Porcine Caudal Dorsal Root Ganglia in Tail Amputated Pigs Shows Long-Term Effects on Many Pain-Associated Genes

Frontiers in veterinary science, 2019-09, Vol.6, p.314-314

2019

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The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single-Cell Resolution

Cancer discovery, 2022-06, Vol.12 (6), p.1518-1541

2022

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MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging

Nature methods, 2022-03, Vol.19 (3), p.311-315

2022

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Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma

Cancer cell, 2023-05, Vol.41 (5), p.871-886.e10

2023

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Immune Profiling of Dermatologic Adverse Events from Checkpoint Blockade Using Tissue Cyclic Immunofluorescence: A Pilot Study

Journal of investigative dermatology, 2024-08, Vol.144 (8), p.1887-1890.e5

2024

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SCIMAP: A Python Toolkit for Integrated Spatial Analysis of Multiplexed Imaging Data

Journal of open source software, 2024-01, Vol.9 (97), p.6604

2024

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Development and validation of time-to-event models to predict metastatic recurrence of localized cutaneous melanoma

Journal of the American Academy of Dermatology, 2024-02, Vol.90 (2), p.288-298

2024

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Macrophage colony-stimulating factor increases hepatic macrophage content, liver growth, and lipid accumulation in neonatal rats

American journal of physiology: Gastrointestinal and liver physiology, 2018-03, Vol.314 (3), p.G388-G398

2018

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SpatialCells: automated profiling of tumor microenvironments with spatially resolved multiplexed single-cell data

Briefings in bioinformatics, 2024-03, Vol.25 (3)

2024

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Derivation of marker gene signatures from human skin and their use in the interpretation of the transcriptional changes associated with dermatological disorders

The Journal of pathology, 2017-04, Vol.241 (5), p.600-613

2017

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TP63 fusions drive multicomplex enhancer rewiring, lymphomagenesis, and EZH2 dependence

Science translational medicine, 2023-09, Vol.15 (714), p.eadi7244

2023

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Single Cell Spatial Biology for Precision Cancer Medicine

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 2023, Vol.28, p.549

2023

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Durable engraftment of genetically modified FVIII‐secreting autologous bone marrow stromal cells in the intramedullary microenvironment

Journal of cellular and molecular medicine, 2018-07, Vol.22 (7), p.3698-3702

2018

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The 2023 generation

Nature cancer, 2023-12, Vol.4 (12), p.1630-1635

2023

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Abstract A080: CD8+T-cell interplay with myeloid cells as spatial determinant of chemotherapy response in the tumor microenvironment of metastatic high-grade serous ovarian cancer

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (5_Supplement_2), p.A080-A080

2024

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Abstract 5706: ImmunoPROFILE: A prospective implementation of clinically validated, quantitative immune cell profiling test identifies tumor-infiltrating CD8+ and PD-1+ cell densities as prognostic biomarkers across a 2,023 patient pan-cancer cohort treated with different therapies

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.5706-5706

2023

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Abstract 5877: Intratumoral lymphocyte networks harbor TCF1+ PD1+ progenitor CD8 T cells in lung cancer

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.5877-5877

2023

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The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single Cell Resolution

SSRN Electronic Journal

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Lymphocyte Networks are Dynamic Cellular Communities in the Immunoregulatory Landscape of Lung Adenocarcinoma

SSRN Electronic Journal

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Discovery and pre-clinical characterization of a selective PI3Kδ inhibitor, LL-00071210 in rheumatoid arthritis

European journal of pharmacology, 2022-07, Vol.927, p.175054-175054, Article 175054

2022

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Discovery of a Potent and Selective PI3Kδ Inhibitor ( S )-2,4-Diamino-6-((1-(7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenyl-4 H -quinolizin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile with Improved Pharmacokinetic Profile and Superior Efficacy in Hematological Cancer Models

Journal of medicinal chemistry, 2020-12, Vol.63 (23), p.14700-14723

2020

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Immune Cell Gene Signatures for Profiling the Microenvironment of Solid Tumors

Multiplexed and reproducible high content screening of live and fixed cells using Dye Drop

Transcriptomics Analysis of Porcine Caudal Dorsal Root Ganglia in Tail Amputated Pigs Shows Long-Term Effects on Many Pain-Associated Genes

The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single-Cell Resolution

MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging

Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma

Immune Profiling of Dermatologic Adverse Events from Checkpoint Blockade Using Tissue Cyclic Immunofluorescence: A Pilot Study

SCIMAP: A Python Toolkit for Integrated Spatial Analysis of Multiplexed Imaging Data

Overcoming IMiD resistance in T-cell lymphomas through potent degradation of ZFP91 and IKZF1

Duvelisib plus romidepsin in relapsed/refractory T cell lymphomas: a phase 1b/2a trial

Development and validation of time-to-event models to predict metastatic recurrence of localized cutaneous melanoma

Macrophage colony-stimulating factor increases hepatic macrophage content, liver growth, and lipid accumulation in neonatal rats

SpatialCells: automated profiling of tumor microenvironments with spatially resolved multiplexed single-cell data

Derivation of marker gene signatures from human skin and their use in the interpretation of the transcriptional changes associated with dermatological disorders

TP63 fusions drive multicomplex enhancer rewiring, lymphomagenesis, and EZH2 dependence

Single Cell Spatial Biology for Precision Cancer Medicine

Durable engraftment of genetically modified FVIII‐secreting autologous bone marrow stromal cells in the intramedullary microenvironment

The 2023 generation

Abstract A080: CD8+T-cell interplay with myeloid cells as spatial determinant of chemotherapy response in the tumor microenvironment of metastatic high-grade serous ovarian cancer

Abstract 5706: ImmunoPROFILE: A prospective implementation of clinically validated, quantitative immune cell profiling test identifies tumor-infiltrating CD8+ and PD-1+ cell densities as prognostic biomarkers across a 2,023 patient pan-cancer cohort treated with different therapies

Abstract 5877: Intratumoral lymphocyte networks harbor TCF1+ PD1+ progenitor CD8 T cells in lung cancer

The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single Cell Resolution

Lymphocyte Networks are Dynamic Cellular Communities in the Immunoregulatory Landscape of Lung Adenocarcinoma

Discovery and pre-clinical characterization of a selective PI3Kδ inhibitor, LL-00071210 in rheumatoid arthritis

Discovery of a Potent and Selective PI3Kδ Inhibitor ( S )-2,4-Diamino-6-((1-(7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenyl-4 H -quinolizin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile with Improved Pharmacokinetic Profile and Superior Efficacy in Hematological Cancer Models

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