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Osteoarthritis as a disease of the cartilage pericellular matrix

Matrix biology, 2018-10, Vol.71-72, p.40-50

2018

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Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis

Proceedings of the National Academy of Sciences - PNAS, 2021-03, Vol.118 (13)

2021

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Regulation of chondrocyte biosynthetic activity by dynamic hydrostatic pressure: the role of TRP channels

Connective tissue research, 2022-01, Vol.63 (1), p.69-81

2022

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Designer Stem Cells: Genome Engineering and the Next Generation of Cell‐Based Therapies

Journal of orthopaedic research, 2019-06, Vol.37 (6), p.1287-1293

2019

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Accumulation of Exogenous Activated TGF-β in the Superficial Zone of Articular Cartilage

Biophysical journal, 2013-04, Vol.104 (8), p.1794-1804

2013

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Shearing of synovial fluid activates latent TGF-β

Osteoarthritis and cartilage, 2012-11, Vol.20 (11), p.1374-1382

2012

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Mechanogenetics: harnessing mechanobiology for cellular engineering

Current opinion in biotechnology, 2022-02, Vol.73, p.374-379

2022

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A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues

Science advances, 2021-01, Vol.7 (5)

2021

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Nutrient Channels Aid the Growth of Articular Surface-Sized Engineered Cartilage Constructs

Tissue engineering. Part A, 2016-09, Vol.22 (17-18), p.1063-1074

2016

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Time and dose-dependent effects of chondroitinase ABC on growth of engineered cartilage

European Cells and Materials, 2014-04, Vol.27, p.312-320

2014

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Optimizing nutrient channel spacing and revisiting TGF-beta in large engineered cartilage constructs

Journal of biomechanics, 2016-07, Vol.49 (10), p.2089-2094

2016

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Immunoengineering the next generation of arthritis therapies

Acta biomaterialia, 2021-10, Vol.133, p.74-86

2021

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Membrane stretch as the mechanism of activation of PIEZO1 ion channels in chondrocytes

Proceedings of the National Academy of Sciences - PNAS, 2023-07, Vol.120 (30), p.e2221958120-e2221958120

2023

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Direct Osmotic Pressure Measurements in Articular Cartilage Demonstrate Nonideal and Concentration-Dependent Phenomena

Journal of biomechanical engineering, 2021-04, Vol.143 (4)

2021

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Standards for vision science libraries: 2014 revision

Journal of the Medical Library Association, 2014-10, Vol.102 (4), p.288-291

2014

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Heterogeneous engineered cartilage growth results from gradients of media-supplemented active TGF-β and is ameliorated by the alternative supplementation of latent TGF-β

Biomaterials, 2016-01, Vol.77, p.173-185

2016

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Immature bovine cartilage wear by fatigue failure and delamination

Journal of biomechanics, 2020-06, Vol.107, p.109852-109852, Article 109852

2020

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High seeding density of human chondrocytes in agarose produces tissue-engineered cartilage approaching native mechanical and biochemical properties

Journal of biomechanics, 2016-06, Vol.49 (9), p.1909-1917

2016

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Reactive Constrained Mixtures for Modeling the Solid Matrix of Biological Tissues

Journal of elasticity, 2017-12, Vol.129 (1-2), p.69-105

2017

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Combined Experimental Approach and Finite Element Modeling of Small Molecule Transport Through Joint Synovium to Measure Effective Diffusivity

Journal of biomechanical engineering, 2020-04, Vol.142 (4)

2020

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Synthesis rates and binding kinetics of matrix products in engineered cartilage constructs using chondrocyte-seeded agarose gels

Journal of biomechanics, 2014-06, Vol.47 (9), p.2165-2172

2014

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Computational modeling of chemical reactions and interstitial growth and remodeling involving charged solutes and solid-bound molecules

Biomechanics and modeling in mechanobiology, 2014-10, Vol.13 (5), p.1105-1120

2014

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Nutrient channels and stirring enhanced the composition and stiffness of large cartilage constructs

Journal of biomechanics, 2014-12, Vol.47 (16), p.3847-3854

2014

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Constrained Cage Culture Improves Engineered Cartilage Functional Properties by Enhancing Collagen Network Stability

Tissue engineering. Part A, 2017-08, Vol.23 (15-16), p.847-858

2017

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Matrix Production in Large Engineered Cartilage Constructs Is Enhanced by Nutrient Channels and Excess Media Supply

Tissue engineering. Part C, Methods, 2015-07, Vol.21 (7), p.747-757

2015

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Osteoarthritis as a disease of the cartilage pericellular matrix

Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis

Regulation of chondrocyte biosynthetic activity by dynamic hydrostatic pressure: the role of TRP channels

Designer Stem Cells: Genome Engineering and the Next Generation of Cell‐Based Therapies

Accumulation of Exogenous Activated TGF-β in the Superficial Zone of Articular Cartilage

Shearing of synovial fluid activates latent TGF-β

Mechanogenetics: harnessing mechanobiology for cellular engineering

A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues

Nutrient Channels Aid the Growth of Articular Surface-Sized Engineered Cartilage Constructs

Time and dose-dependent effects of chondroitinase ABC on growth of engineered cartilage

Optimizing nutrient channel spacing and revisiting TGF-beta in large engineered cartilage constructs

Immunoengineering the next generation of arthritis therapies

Membrane stretch as the mechanism of activation of PIEZO1 ion channels in chondrocytes

Direct Osmotic Pressure Measurements in Articular Cartilage Demonstrate Nonideal and Concentration-Dependent Phenomena

Standards for vision science libraries: 2014 revision

Heterogeneous engineered cartilage growth results from gradients of media-supplemented active TGF-β and is ameliorated by the alternative supplementation of latent TGF-β

Immature bovine cartilage wear by fatigue failure and delamination

High seeding density of human chondrocytes in agarose produces tissue-engineered cartilage approaching native mechanical and biochemical properties

Reactive Constrained Mixtures for Modeling the Solid Matrix of Biological Tissues

Combined Experimental Approach and Finite Element Modeling of Small Molecule Transport Through Joint Synovium to Measure Effective Diffusivity

Synthesis rates and binding kinetics of matrix products in engineered cartilage constructs using chondrocyte-seeded agarose gels

Computational modeling of chemical reactions and interstitial growth and remodeling involving charged solutes and solid-bound molecules

Nutrient channels and stirring enhanced the composition and stiffness of large cartilage constructs

Constrained Cage Culture Improves Engineered Cartilage Functional Properties by Enhancing Collagen Network Stability

Matrix Production in Large Engineered Cartilage Constructs Is Enhanced by Nutrient Channels and Excess Media Supply

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