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Method to generate highly stable D-amino acid analogs of bioactive helical peptides using a mirror image of the entire PDB

Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (7), p.1505-1510

2018

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Strategies to Develop Inhibitors of Motif-Mediated Protein-Protein Interactions as Drug Leads

Annual review of pharmacology and toxicology, 2017-01, Vol.57, p.39

2017

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Discovery of short linear motif‐mediated interactions through phage display of intrinsically disordered regions of the human proteome

The FEBS journal, 2017-02, Vol.284 (3), p.485-498

2017

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Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (7), p.2542-2547

2014

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Rapid and accurate structure‐based therapeutic peptide design using GPU accelerated thermodynamic integration

Proteins, structure, function, and bioinformatics, 2019-03, Vol.87 (3), p.236-244

2019

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Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson's disease

Nature communications, 2023-04, Vol.14 (1), p.2150-2150, Article 2150

2023

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PepNN: a deep attention model for the identification of peptide binding sites

Communications biology, 2022-05, Vol.5 (1), p.503-503, Article 503

2022

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A systematic approach to identify novel cancer drug targets using machine learning, inhibitor design and high-throughput screening

Genome medicine, 2014-07, Vol.6 (7), p.57-57, Article 57

2014

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Pooled screening for antiproliferative inhibitors of protein-protein interactions

Nature chemical biology, 2016-04, Vol.12 (4), p.275

2016

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Subcellular localization of coagulation factor II receptor-like 1 in neurons governs angiogenesis

Nature Medicine, 2014-10, Vol.20 (10), p.1165-1173

2014

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Caveolin‐1 regulation of dynamin‐dependent, raft‐mediated endocytosis of cholera toxin–B sub‐unit occurs independently of caveolae

Journal of cellular and molecular medicine, 2009-09, Vol.13 (9b), p.3218-3225

2009

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Apoptosis Detected in the Amygdala Following Myocardial Infarction in the Rat

Biological psychiatry (1969), 2006-03, Vol.59 (5), p.430-433

2006

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Computational Design of Potent and Selective d‑Peptide Agonists of the Glucagon-like Peptide‑2 Receptor

Journal of medicinal chemistry, 2023-08, Vol.66 (15), p.10342-10353

2023

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Computational Design of Potent D‑Peptide Inhibitors of SARS-CoV‑2

Journal of medicinal chemistry, 2021-10, Vol.64 (20), p.14955-14967

2021

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Targeting the Receptor-Binding Motif of SARS-CoV‑2 with D‑Peptides Mimicking the ACE2 Binding Helix: Lessons for Inhibiting Omicron and Future Variants of Concern

Journal of chemical information and modeling, 2022-08, Vol.62 (15), p.3618-3626

2022

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A universal deep-learning model for zinc finger design enables transcription factor reprogramming

Nature biotechnology, 2023-08, Vol.41 (8), p.1117-1129

2023

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Large-Scale Interaction Profiling of Protein Domains Through Proteomic Peptide-Phage Display Using Custom Peptidomes

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1518, p.213

2017

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Abstract 2232: Computational modeling reveals druggable cavities at the MKK3 and p38 protein interaction interface

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.2232-2232

2013

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Generation and Validation of Intracellular Ubiquitin Variant Inhibitors for USP7 and USP10

Journal of molecular biology, 2017-11, Vol.429 (22)

2017

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Early effects of spinal cord transection on skeletal muscle properties

Applied physiology, nutrition, and metabolism, 2006-08, Vol.31 (4), p.398

2006

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Protein engineering by highly parallel screening of computationally designed variants

Science advances, 2016-07, Vol.2 (7), p.e1600692-e1600692

2016

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Proangiogenic effects of protease-activated receptor 2 are tumor necrosis factor-alpha and consecutively Tie2 dependent

Arteriosclerosis, thrombosis, and vascular biology, 2006-04, Vol.26 (4), p.744

2006

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Mechanism of translocation of PAR-2 from the plasma membrane to the nucleus: Implications for angiogenesis and neovascularization

Nim, Satra

2009

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Alterations of β-adrenoceptor responsiveness in postischemic myocardium after 72 h of reperfusion

European journal of pharmacology, 2004-07, Vol.495 (2), p.185-191

2004

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Method to generate highly stable D-amino acid analogs of bioactive helical peptides using a mirror image of the entire PDB

Strategies to Develop Inhibitors of Motif-Mediated Protein-Protein Interactions as Drug Leads

Discovery of short linear motif‐mediated interactions through phage display of intrinsically disordered regions of the human proteome

Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes

Rapid and accurate structure‐based therapeutic peptide design using GPU accelerated thermodynamic integration

Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson's disease

PepNN: a deep attention model for the identification of peptide binding sites

A systematic approach to identify novel cancer drug targets using machine learning, inhibitor design and high-throughput screening

Pooled screening for antiproliferative inhibitors of protein-protein interactions

Subcellular localization of coagulation factor II receptor-like 1 in neurons governs angiogenesis

Caveolin‐1 regulation of dynamin‐dependent, raft‐mediated endocytosis of cholera toxin–B sub‐unit occurs independently of caveolae

Apoptosis Detected in the Amygdala Following Myocardial Infarction in the Rat

Computational Design of Potent and Selective d‑Peptide Agonists of the Glucagon-like Peptide‑2 Receptor

Computational Design of Potent D‑Peptide Inhibitors of SARS-CoV‑2

Targeting the Receptor-Binding Motif of SARS-CoV‑2 with D‑Peptides Mimicking the ACE2 Binding Helix: Lessons for Inhibiting Omicron and Future Variants of Concern

A universal deep-learning model for zinc finger design enables transcription factor reprogramming

Large-Scale Interaction Profiling of Protein Domains Through Proteomic Peptide-Phage Display Using Custom Peptidomes

Abstract 2232: Computational modeling reveals druggable cavities at the MKK3 and p38 protein interaction interface

Generation and Validation of Intracellular Ubiquitin Variant Inhibitors for USP7 and USP10

Early effects of spinal cord transection on skeletal muscle properties

Protein engineering by highly parallel screening of computationally designed variants

Proangiogenic effects of protease-activated receptor 2 are tumor necrosis factor-alpha and consecutively Tie2 dependent

Mechanism of translocation of PAR-2 from the plasma membrane to the nucleus: Implications for angiogenesis and neovascularization

Alterations of β-adrenoceptor responsiveness in postischemic myocardium after 72 h of reperfusion

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