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Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake

The Journal of clinical investigation, 2006-07, Vol.116 (7), p.1955-1962

2006

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First‐in‐Human Evaluation of Oral Denatonium Acetate (ARD‐101), a Potential Bitter Taste Receptor Agonist: A Randomized, Double‐Blind, Placebo‐Controlled Phase 1 Trial in Healthy Adults

Clinical pharmacology in drug development, 2022-08, Vol.11 (8), p.997-1006

2022

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A DNA vaccine against VEGF receptor 2 prevents effective angiogenesis and inhibits tumor growth

Nature medicine, 2002-12, Vol.8 (12), p.1369-1375

2002

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Double-blind, placebo-controlled first in human study to investigate an oral vaccine aimed to elicit an immune reaction against the VEGF-Receptor 2 in patients with stage IV and locally advanced pancreatic cancer

BMC cancer, 2012-08, Vol.12 (1), p.361-361, Article 361

2012

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Multicenter, phase II study of axitinib, a selective second-generation inhibitor of vascular endothelial growth factor receptors 1, 2, and 3, in patients with metastatic melanoma

Clinical cancer research, 2011-12, Vol.17 (23), p.7462-7469

2011

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Oral DNA vaccines target the tumor vasculature and microenvironment and suppress tumor growth and metastasis

Immunological reviews, 2008-04, Vol.222 (1), p.117-128

2008

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Randomized phase II study of pemetrexed/cisplatin with or without axitinib for non-squamous non-small-cell lung cancer

BMC cancer, 2014-04, Vol.14 (1), p.290-290, Article 290

2014

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T cell homeostatic proliferation elicits effective antitumor autoimmunity

The Journal of clinical investigation, 2002-07, Vol.110 (2), p.185-192

2002

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Novel decoy cellular vaccine strategy utilizing transgenic antigen-expressing cells as immune presenter and adjuvant in vaccine prototype against SARS-CoV-2 virus

Medicine in drug discovery, 2020-03, Vol.5, p.100026-100026, Article 100026

2020

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Vaccination against VEGFR2 attenuates initiation and progression of atherosclerosis

Arteriosclerosis, thrombosis, and vascular biology, 2007-09, Vol.27 (9), p.2050-2057

2007

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DNA vaccines suppress tumor growth and metastases by the induction of anti-angiogenesis

Immunological reviews, 2004-06, Vol.199 (1), p.181-190

2004

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A Dual-Function DNA Vaccine Encoding Carcinoembryonic Antigen and CD40 Ligand Trimer Induces T Cell-Mediated Protective Immunity Against Colon Cancer in Carcinoembryonic Antigen-Transgenic Mice

The Journal of immunology (1950), 2001-10, Vol.167 (8), p.4560-4565

2001

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Long-term results of intraoperative presacral electron boost radiotherapy (IOERT) in combination with total mesorectal excision (TME) and chemoradiation in patients with locally advanced rectal cancer

International journal of radiation oncology, biology, physics, 2006-11, Vol.66 (4), p.1143-1151

2006

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Randomized Phase III Trial of Temsirolimus Versus Sorafenib As Second-Line Therapy After Sunitinib in Patients With Metastatic Renal Cell Carcinoma

Journal of clinical oncology, 2014-03, Vol.32 (8), p.760-767

2014

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Intraoperative electron boost radiation followed by moderate doses of external beam radiotherapy in limb-sparing treatment of patients with extremity soft-tissue sarcoma

International journal of radiation oncology, biology, physics, 2006-04, Vol.64 (5), p.1416-1423

2006

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Combination of external-beam radiotherapy with intraoperative electron-beam therapy is effective in incompletely resected pediatric malignancies

International journal of radiation oncology, biology, physics, 2006, Vol.64 (1), p.235-241

2006

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Multidrug resistance-1 (MDR-1): a new target for T cell-based immunotherapy

The FASEB journal, 2005-01, Vol.19 (1), p.158-159

2005

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An oral DNA vaccine against human carcinoembryonic antigen (CEA) prevents growth and dissemination of Lewis lung carcinoma in CEA transgenic mice

Vaccine, 2001-11, Vol.20 (3), p.421-429

2001

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Bisphosphonates and bone metastases: current status and future directions

Expert review of anticancer therapy, 2005-04, Vol.5 (2), p.295-305

2005

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Ralph A. Reisfeld, PhD: In Memoriam (1926–2020)

Cancer research (Chicago, Ill.), 2021-03, Vol.81 (6), p.1429-1430

2021

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Hydrolytically activated etoposide prodrugs inhibit MDR-1 function and eradicate established MDR-1 multidrug-resistant T-cell leukemia

Blood, 2003-07, Vol.102 (1), p.246-253

2003

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Protective Immunity against Human Carcinoembryonic Antigen (CEA) Induced by an Oral DNA Vaccine in CEA-transgenic Mice

Clinical cancer research, 2001-03, Vol.7 (3), p.856s-864s

2001

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IMCT-04TOCA 5: PHASE 2/3 RANDOMIZED, OPEN-LABEL STUDY OF TOCA 511 WITH TOCA FC VERSUS STANDARD OF CARE IN PATIENTS UNDERGOING PLANNED RESECTION FOR RECURRENT HIGH GRADE GLIOMA (NCT02414165)

Neuro-oncology (Charlottesville, Va.), 2015-11, Vol.17 (suppl 5), p.v107.4-v108

2015

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SURG-10TRANSCRANIAL TOCA 511 FOLLOWED BY TOCA FC IN SUBJECTS WITH RECURRENT HIGH GRADE GLIOMA (HGG)

Neuro-oncology (Charlottesville, Va.), 2015-11, Vol.17 (suppl 5), p.v216.2-v216

2015

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Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake

First‐in‐Human Evaluation of Oral Denatonium Acetate (ARD‐101), a Potential Bitter Taste Receptor Agonist: A Randomized, Double‐Blind, Placebo‐Controlled Phase 1 Trial in Healthy Adults

A DNA vaccine against VEGF receptor 2 prevents effective angiogenesis and inhibits tumor growth

Double-blind, placebo-controlled first in human study to investigate an oral vaccine aimed to elicit an immune reaction against the VEGF-Receptor 2 in patients with stage IV and locally advanced pancreatic cancer

Multicenter, phase II study of axitinib, a selective second-generation inhibitor of vascular endothelial growth factor receptors 1, 2, and 3, in patients with metastatic melanoma

Oral DNA vaccines target the tumor vasculature and microenvironment and suppress tumor growth and metastasis

Randomized phase II study of pemetrexed/cisplatin with or without axitinib for non-squamous non-small-cell lung cancer

T cell homeostatic proliferation elicits effective antitumor autoimmunity

Anti-angiogenic activity of VXM01, an oral T-cell vaccine against VEGF receptor 2, in patients with advanced pancreatic cancer: A randomized, placebo-controlled, phase 1 trial

Novel decoy cellular vaccine strategy utilizing transgenic antigen-expressing cells as immune presenter and adjuvant in vaccine prototype against SARS-CoV-2 virus

Vaccination against VEGFR2 attenuates initiation and progression of atherosclerosis

DNA vaccines suppress tumor growth and metastases by the induction of anti-angiogenesis

A Dual-Function DNA Vaccine Encoding Carcinoembryonic Antigen and CD40 Ligand Trimer Induces T Cell-Mediated Protective Immunity Against Colon Cancer in Carcinoembryonic Antigen-Transgenic Mice

Long-term results of intraoperative presacral electron boost radiotherapy (IOERT) in combination with total mesorectal excision (TME) and chemoradiation in patients with locally advanced rectal cancer

Randomized Phase III Trial of Temsirolimus Versus Sorafenib As Second-Line Therapy After Sunitinib in Patients With Metastatic Renal Cell Carcinoma

Intraoperative electron boost radiation followed by moderate doses of external beam radiotherapy in limb-sparing treatment of patients with extremity soft-tissue sarcoma

Combination of external-beam radiotherapy with intraoperative electron-beam therapy is effective in incompletely resected pediatric malignancies

Multidrug resistance-1 (MDR-1): a new target for T cell-based immunotherapy

An oral DNA vaccine against human carcinoembryonic antigen (CEA) prevents growth and dissemination of Lewis lung carcinoma in CEA transgenic mice

Bisphosphonates and bone metastases: current status and future directions

Ralph A. Reisfeld, PhD: In Memoriam (1926–2020)

Hydrolytically activated etoposide prodrugs inhibit MDR-1 function and eradicate established MDR-1 multidrug-resistant T-cell leukemia

Protective Immunity against Human Carcinoembryonic Antigen (CEA) Induced by an Oral DNA Vaccine in CEA-transgenic Mice

IMCT-04TOCA 5: PHASE 2/3 RANDOMIZED, OPEN-LABEL STUDY OF TOCA 511 WITH TOCA FC VERSUS STANDARD OF CARE IN PATIENTS UNDERGOING PLANNED RESECTION FOR RECURRENT HIGH GRADE GLIOMA (NCT02414165)

SURG-10TRANSCRANIAL TOCA 511 FOLLOWED BY TOCA FC IN SUBJECTS WITH RECURRENT HIGH GRADE GLIOMA (HGG)

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