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New Approaches to Drug Discovery

1st ed. 2016, 2016

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Suppressor of Cytokine Signaling-3 Is Recruited to the Activated Granulocyte-Colony Stimulating Factor Receptor and Modulates its Signal Transduction

The Journal of immunology (1950), 2002-08, Vol.169 (3), p.1219-1227

2002

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Pharmacokinetics in Drug Discovery: An Exposure-Centred Approach to Optimising and Predicting Drug Efficacy and Safety

Handbook of experimental pharmacology, 2016, Vol.232, p.235-260

2016

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The last decade has seen many exciting new medicines being introduced to the market. Introduction

Handbook of experimental pharmacology, 2016, Vol.232, p.v

2016

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Translational In Vivo Models for Women’s Health: The Nonhuman Primate Endometrium—A Predictive Model for Assessing Steroid Receptor Modulators

Handbook of experimental pharmacology, 2016-01, Vol.232, p.191-202

2016

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Trends in Modern Drug Discovery

Handbook of experimental pharmacology, 2016, Vol.232, p.3-22

2016

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Using Cheminformatics in Drug Discovery

Handbook of experimental pharmacology, 2016, Vol.232, p.139-168

2016

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A new high affinity binding site for suppressor of cytokine signaling‐3 on the erythropoietin receptor

European journal of biochemistry, 2002-05, Vol.269 (10), p.2516-2526

2002

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Comparing the global mRNA expression profile of human atrial and ventricular myocardium with high-density oligonucleotide arrays

The Journal of thoracic and cardiovascular surgery, 2005-06, Vol.129 (6), p.1383-1390

2005

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Implementation and Use of State-of-the-Art, Cell-Based In Vitro Assays

Handbook of experimental pharmacology, 2016, Vol.232, p.171-190

2016

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Sources for Leads: Natural Products and Libraries

Handbook of experimental pharmacology, 2016, Vol.232, p.91-123

2016

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Impact of Biomarkers on Personalized Medicine

Handbook of experimental pharmacology, 2016, Vol.232, p.285-311

2016

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Emerging Target Families: Intractable Targets

Handbook of experimental pharmacology, 2016, Vol.232, p.43-58

2016

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Predictive In Vivo Models for Oncology

Handbook of experimental pharmacology, 2016, Vol.232, p.203-221

2016

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Nonclinical Safety and Toxicology

Handbook of experimental pharmacology, 2016, Vol.232, p.261-283

2016

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Modeling and Simulation of In Vivo Drug Effects

Handbook of experimental pharmacology, 2016, Vol.232, p.313-329

2016

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In Vivo Target Validation Using Biological Molecules in Drug Development

Handbook of experimental pharmacology, 2016, Vol.232, p.59-70

2016

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New Compound Classes: Protein-Protein Interactions

Handbook of experimental pharmacology, 2016, Vol.232, p.125-138

2016

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Translational In Vivo Models for Cardiovascular Diseases

Handbook of experimental pharmacology, 2016, Vol.232, p.223-234

2016

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Functional Genomics in Pharmaceutical Drug Discovery

Handbook of experimental pharmacology, 2016, Vol.232, p.25-41

2016

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High-Throughput Synthesis of Diverse Compound Collections for Lead Discovery and Optimization

Handbook of experimental pharmacology, 2016, Vol.232, p.73-89

2016

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One target – multiple indications: a call for an integrated common mechanisms strategy

Drug discovery today, 2007-12, Vol.12 (23), p.1025-1031

2007

Volltextzugriff (PDF)

Changes in NF‐kappa B and ISGF3 DNA binding activities are responsible for differences in MHC and beta‐IFN gene expression in Ad5‐ versus Ad12‐transformed cells

The EMBO journal, 1991-12, Vol.10 (13), p.4169-4175

1991

Volltextzugriff (PDF)

Translational In Vivo Models for Women´s Health: The Nonhuman Primate Endometrium-A Predictive Model for Assessing Steroid Rec

New Approaches to Drug Discovery, 2016, Vol.232

2016

Volltextzugriff (PDF)

Intro

New Approaches to Drug Discovery, 2016, Vol.232

2016

Volltextzugriff (PDF)

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New Approaches to Drug Discovery

Suppressor of Cytokine Signaling-3 Is Recruited to the Activated Granulocyte-Colony Stimulating Factor Receptor and Modulates its Signal Transduction

Pharmacokinetics in Drug Discovery: An Exposure-Centred Approach to Optimising and Predicting Drug Efficacy and Safety

The last decade has seen many exciting new medicines being introduced to the market. Introduction

Translational In Vivo Models for Women’s Health: The Nonhuman Primate Endometrium—A Predictive Model for Assessing Steroid Receptor Modulators

Trends in Modern Drug Discovery

Using Cheminformatics in Drug Discovery

A new high affinity binding site for suppressor of cytokine signaling‐3 on the erythropoietin receptor

Comparing the global mRNA expression profile of human atrial and ventricular myocardium with high-density oligonucleotide arrays

Implementation and Use of State-of-the-Art, Cell-Based In Vitro Assays

Sources for Leads: Natural Products and Libraries

Impact of Biomarkers on Personalized Medicine

Emerging Target Families: Intractable Targets

Predictive In Vivo Models for Oncology

Nonclinical Safety and Toxicology

Modeling and Simulation of In Vivo Drug Effects

In Vivo Target Validation Using Biological Molecules in Drug Development

New Compound Classes: Protein-Protein Interactions

Translational In Vivo Models for Cardiovascular Diseases

Functional Genomics in Pharmaceutical Drug Discovery

High-Throughput Synthesis of Diverse Compound Collections for Lead Discovery and Optimization

One target – multiple indications: a call for an integrated common mechanisms strategy

Changes in NF‐kappa B and ISGF3 DNA binding activities are responsible for differences in MHC and beta‐IFN gene expression in Ad5‐ versus Ad12‐transformed cells

Translational In Vivo Models for Women´s Health: The Nonhuman Primate Endometrium-A Predictive Model for Assessing Steroid Rec

Intro

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