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The Past, Present, and Future of Non-Viral CAR T Cells

Frontiers in immunology, 2022-06, Vol.13, p.867013-867013

2022

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A review of the clinical experience with CMN-001, a tumor RNA loaded dendritic cell immunotherapy for the treatment of metastatic renal cell carcinoma

Human vaccines & immunotherapeutics, 2023-08, Vol.19 (2), p.2220629-2220629

2023

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Results of the ADAPT Phase 3 Study of Rocapuldencel-T in Combination with Sunitinib as First-Line Therapy in Patients with Metastatic Renal Cell Carcinoma

Clinical cancer research, 2020-05, Vol.26 (10), p.2327-2336

2020

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Soluble CD83 Inhibits T Cell Activation by Binding to the TLR4/MD-2 Complex on CD14 + Monocytes

The Journal of immunology (1950), 2017-03, Vol.198 (6), p.2286-2301

2017

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Immunogenicity of AGS-004 Dendritic Cell Therapy in Patients Treated During Acute HIV Infection

AIDS research and human retroviruses, 2018-01, Vol.34 (1), p.111

2018

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Assessing the impact of AGS-004, a dendritic cell-based immunotherapy, and vorinostat on persistent HIV-1 Infection

Scientific reports, 2020-03, Vol.10 (1), p.5134-5134, Article 5134

2020

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Survival with AGS-003, an autologous dendritic cell-based immunotherapy, in combination with sunitinib in unfavorable risk patients with advanced renal cell carcinoma (RCC): Phase 2 study results

Journal for immunotherapy of cancer, 2015-04, Vol.3 (1), p.14-14, Article 14

2015

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A Short Pulse of IL-4 Delivered by DCs Electroporated With Modified mRNA Can Both Prevent and Treat Autoimmune Diabetes in NOD Mice

Molecular therapy, 2010-12, Vol.18 (12), p.2112-2120

2010

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Ectopic expression of a truncated CD40L protein from synthetic post-transcriptionally capped RNA in dendritic cells induces high levels of IL-12 secretion

BMC molecular biology, 2008-10, Vol.9 (1), p.90-90

2008

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Multiplex RT-PCR amplification of HIV genes to create a completely autologous DC-based immunotherapy for the treatment of HIV infection

PloS one, 2008-01, Vol.3 (1), p.e1489-e1489

2008

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Evaluation of a microfluidics-based platform and slab electrophoresis for determination of size, integrity and quantification of in vitro transcribed RNA used as a component in therapeutic drug manufacturing

Journal of pharmaceutical and biomedical analysis, 2012-11, Vol.70, p.657-663

2012

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Prevention of chronic renal allograft rejection by soluble CD83

Transplantation, 2010-12, Vol.90 (12), p.1278

2010

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Potency of mature CD40L RNA electroporated dendritic cells correlates with IL-12 secretion by tracking multifunctional CD8(+)/CD28(+) cytotoxic T-cell responses in vitro

Journal of immunotherapy (1997), 2011-01, Vol.34 (1), p.45

2011

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Priming of a Novel Subset of CD28+ Rapidly Expanding High-Avidity Effector Memory CTL by Post Maturation Electroporation-CD40L Dendritic Cells Is IL-12 Dependent

The Journal of immunology (1950), 2008-10, Vol.181 (8), p.5296-5305

2008

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Cytokine maturation followed by CD40L mRNA electroporation results in a clinically relevant dendritic cell product capable of inducing a potent proinflammatory CTL response

Journal of immunotherapy, 2008-10, Vol.31 (8), p.731-741

2008

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Evaluation of RNA Amplification Methods to Improve DC Immunotherapy Antigen Presentation and Immune Response

Molecular therapy. Nucleic acids, 2013-05, Vol.2 (5), p.e91-e91, Article e91

2013

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The immunosuppressive properties of the HIV Vpr protein are linked to a single highly conserved residue, R90

PloS one, 2009-06, Vol.4 (6), p.e5853-e5853

2009

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Structural identification of recombinant human CD83 mutant variant as a potent therapeutic protein

Protein expression and purification, 2010-10, Vol.73 (2), p.140-146

2010

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The identification of clinically relevant markers and therapeutic targets

Drug Discovery Today, 2003, Vol.8 (1), p.31-38

2003

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Dendritic Cell Immunotherapy for HIV-1 Infection Using Autologous HIV-1 RNA: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Journal of acquired immune deficiency syndromes (1999), 2016-05, Vol.72 (1), p.31

2016

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Topical application of soluble CD83 induces IDO-mediated immune modulation, increases Foxp3+ T cells, and prolongs allogeneic corneal graft survival

The Journal of immunology (1950), 2013-08, Vol.191 (4), p.1965-1975

2013

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Reduced Chronic Lymphocyte Activation following Interferon Alpha Blockade during the Acute Phase of Simian Immunodeficiency Virus Infection in Rhesus Macaques

Journal of virology, 2018-05, Vol.92 (9)

2018

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Interim data analysis of the ADAPT trial using the modified intent to treat (mITT) population re-evaluates Rocapuldencel-T for clinical benefit over standard of care

Journal of clinical oncology, 2018-05, Vol.36 (15_suppl), p.4557-4557

2018

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A high-throughput proteo-genomics method to identify antibody targets associated with malignant disease

Clinical immunology (Orlando, Fla.), 2004-05, Vol.111 (2), p.202-209

2004

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Development of a novel immunotherapy for muscle invasive bladder cancer (MIBC)

Journal of clinical oncology, 2017-02, Vol.35 (6_suppl), p.402-402

2017

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The Past, Present, and Future of Non-Viral CAR T Cells

A review of the clinical experience with CMN-001, a tumor RNA loaded dendritic cell immunotherapy for the treatment of metastatic renal cell carcinoma

Results of the ADAPT Phase 3 Study of Rocapuldencel-T in Combination with Sunitinib as First-Line Therapy in Patients with Metastatic Renal Cell Carcinoma

Soluble CD83 Inhibits T Cell Activation by Binding to the TLR4/MD-2 Complex on CD14 + Monocytes

Immunogenicity of AGS-004 Dendritic Cell Therapy in Patients Treated During Acute HIV Infection

Assessing the impact of AGS-004, a dendritic cell-based immunotherapy, and vorinostat on persistent HIV-1 Infection

Survival with AGS-003, an autologous dendritic cell-based immunotherapy, in combination with sunitinib in unfavorable risk patients with advanced renal cell carcinoma (RCC): Phase 2 study results

A Short Pulse of IL-4 Delivered by DCs Electroporated With Modified mRNA Can Both Prevent and Treat Autoimmune Diabetes in NOD Mice

Ectopic expression of a truncated CD40L protein from synthetic post-transcriptionally capped RNA in dendritic cells induces high levels of IL-12 secretion

Multiplex RT-PCR amplification of HIV genes to create a completely autologous DC-based immunotherapy for the treatment of HIV infection

Evaluation of a microfluidics-based platform and slab electrophoresis for determination of size, integrity and quantification of in vitro transcribed RNA used as a component in therapeutic drug manufacturing

Prevention of chronic renal allograft rejection by soluble CD83

Potency of mature CD40L RNA electroporated dendritic cells correlates with IL-12 secretion by tracking multifunctional CD8(+)/CD28(+) cytotoxic T-cell responses in vitro

Priming of a Novel Subset of CD28+ Rapidly Expanding High-Avidity Effector Memory CTL by Post Maturation Electroporation-CD40L Dendritic Cells Is IL-12 Dependent

Cytokine maturation followed by CD40L mRNA electroporation results in a clinically relevant dendritic cell product capable of inducing a potent proinflammatory CTL response

Evaluation of RNA Amplification Methods to Improve DC Immunotherapy Antigen Presentation and Immune Response

The immunosuppressive properties of the HIV Vpr protein are linked to a single highly conserved residue, R90

Structural identification of recombinant human CD83 mutant variant as a potent therapeutic protein

The identification of clinically relevant markers and therapeutic targets

Dendritic Cell Immunotherapy for HIV-1 Infection Using Autologous HIV-1 RNA: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Topical application of soluble CD83 induces IDO-mediated immune modulation, increases Foxp3+ T cells, and prolongs allogeneic corneal graft survival

Reduced Chronic Lymphocyte Activation following Interferon Alpha Blockade during the Acute Phase of Simian Immunodeficiency Virus Infection in Rhesus Macaques

Interim data analysis of the ADAPT trial using the modified intent to treat (mITT) population re-evaluates Rocapuldencel-T for clinical benefit over standard of care

A high-throughput proteo-genomics method to identify antibody targets associated with malignant disease

Development of a novel immunotherapy for muscle invasive bladder cancer (MIBC)

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