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Promiscuity and specificity in BMP receptor activation

FEBS letters, 2012-07, Vol.586 (14), p.1846-1859

2012

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Specification of BMP Signaling

Cells (Basel, Switzerland), 2019-12, Vol.8 (12), p.1579

2019

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Unraveling the Connection between Fibroblast Growth Factor and Bone Morphogenetic Protein Signaling

International journal of molecular sciences, 2018-10, Vol.19 (10), p.3220

2018

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Release and bioactivity of bone morphogenetic protein-2 are affected by scaffold binding techniques in vitro and in vivo

Journal of controlled release, 2015-01, Vol.197, p.148-157

2015

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Enhanced reconstruction of long bone architecture by a growth factor mutant combining positive features of GDF-5 and BMP-2

Biomaterials, 2013-08, Vol.34 (24), p.5926-5936

2013

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Receptor oligomerization and beyond: a case study in bone morphogenetic proteins

BMC biology, 2009-09, Vol.7 (1), p.59-59, Article 59

2009

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Site-Directed Immobilization of an Engineered Bone Morphogenetic Protein 2 (BMP2) Variant to Collagen-Based Microspheres Induces Bone Formation In Vivo

International journal of molecular sciences, 2022-04, Vol.23 (7), p.3928

2022

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Growth on Metallo-Supramolecular Coordination Polyelectrolyte (MEPE) Stimulates Osteogenic Differentiation of Human Osteosarcoma Cells (MG63) and Human Bone Marrow Derived Mesenchymal Stem Cells

Polymers, 2019-06, Vol.11 (7), p.1090

2019

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Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity

The EMBO journal, 2009-04, Vol.28 (7), p.937-947

2009

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GDF-5 can act as a context-dependent BMP-2 antagonist

BMC biology, 2015-09, Vol.13 (1), p.77-77, Article 77

2015

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The anti-myeloma activity of bone morphogenetic protein 2 predominantly relies on the induction of growth arrest and is apoptosis-independent

PloS one, 2017-10, Vol.12 (10), p.e0185720-e0185720

2017

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Comparative in vitro treatment of mesenchymal stromal cells with GDF-5 and R57A induces chondrogenic differentiation while limiting chondrogenic hypertrophy

Journal of experimental orthopaedics, 2023-03, Vol.10 (1), p.29-n/a

2023

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Anisotropic Cryostructured Collagen Scaffolds for Efficient Delivery of RhBMP–2 and Enhanced Bone Regeneration

Materials, 2019-09, Vol.12 (19), p.3105

2019

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Utilizing BMP-2 muteins for treatment of multiple myeloma

PloS one, 2017-05, Vol.12 (5), p.e0174884-e0174884

2017

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Functional Antibodies Targeting IsaA of Staphylococcus aureus Augment Host Immune Response and Open New Perspectives for Antibacterial Therapy

Antimicrobial Agents and Chemotherapy, 2011-01, Vol.55 (1), p.165-173

2011

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von Willebrand Factor Type C Domain-containing Proteins Regulate Bone Morphogenetic Protein Signaling through Different Recognition Mechanisms

The Journal of biological chemistry, 2007-07, Vol.282 (27), p.20002-20014

2007

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Addition of heparin binding sites strongly increases the bone forming capabilities of BMP9 in vivo

Bioactive materials, 2023-11, Vol.29, p.241-250

2023

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Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand

The FEBS journal, 2008-01, Vol.275 (1), p.172-183

2008

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Molecular recognition of BMP-2 and BMP receptor IA

Nature structural & molecular biology, 2004-05, Vol.11 (5), p.481-488

2004

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Identification of a Novel TGF-β-Binding Site in the Zona Pellucida C-terminal (ZP-C) Domain of TGF-β-Receptor-3 (TGFR-3)

PloS one, 2013-06, Vol.8 (6), p.e67214-e67214

2013

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Effectiveness of BMP-2 and PDGF-BB Adsorption onto a Collagen/Collagen-Magnesium-Hydroxyapatite Scaffold in Weight-Bearing and Non-Weight-Bearing Osteochondral Defect Bone Repair: In Vitro, Ex Vivo and In Vivo Evaluation

Journal of functional biomaterials, 2023-02, Vol.14 (2), p.111

2023

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A GDF5 point mutation strikes twice--causing BDA1 and SYNS2

PLoS genetics, 2013-10, Vol.9 (10), p.e1003846-e1003846

2013

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Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN

PLoS genetics, 2009-11, Vol.5 (11), p.e1000747-e1000747

2009

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Molecular recognition in bone morphogenetic protein (BMP)/receptor interaction

Biological chemistry, 2004-08, Vol.385 (8), p.697-710

2004

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Structure Analysis of Bone Morphogenetic Protein-2 Type I Receptor Complexes Reveals a Mechanism of Receptor Inactivation in Juvenile Polyposis Syndrome

The Journal of biological chemistry, 2008-02, Vol.283 (9), p.5876-5887

2008

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Promiscuity and specificity in BMP receptor activation

Specification of BMP Signaling

Unraveling the Connection between Fibroblast Growth Factor and Bone Morphogenetic Protein Signaling

Release and bioactivity of bone morphogenetic protein-2 are affected by scaffold binding techniques in vitro and in vivo

Enhanced reconstruction of long bone architecture by a growth factor mutant combining positive features of GDF-5 and BMP-2

Receptor oligomerization and beyond: a case study in bone morphogenetic proteins

Site-Directed Immobilization of an Engineered Bone Morphogenetic Protein 2 (BMP2) Variant to Collagen-Based Microspheres Induces Bone Formation In Vivo

Growth on Metallo-Supramolecular Coordination Polyelectrolyte (MEPE) Stimulates Osteogenic Differentiation of Human Osteosarcoma Cells (MG63) and Human Bone Marrow Derived Mesenchymal Stem Cells

Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity

GDF-5 can act as a context-dependent BMP-2 antagonist

The anti-myeloma activity of bone morphogenetic protein 2 predominantly relies on the induction of growth arrest and is apoptosis-independent

Comparative in vitro treatment of mesenchymal stromal cells with GDF-5 and R57A induces chondrogenic differentiation while limiting chondrogenic hypertrophy

Anisotropic Cryostructured Collagen Scaffolds for Efficient Delivery of RhBMP–2 and Enhanced Bone Regeneration

Utilizing BMP-2 muteins for treatment of multiple myeloma

Functional Antibodies Targeting IsaA of Staphylococcus aureus Augment Host Immune Response and Open New Perspectives for Antibacterial Therapy

von Willebrand Factor Type C Domain-containing Proteins Regulate Bone Morphogenetic Protein Signaling through Different Recognition Mechanisms

Addition of heparin binding sites strongly increases the bone forming capabilities of BMP9 in vivo

Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand

Molecular recognition of BMP-2 and BMP receptor IA

Identification of a Novel TGF-β-Binding Site in the Zona Pellucida C-terminal (ZP-C) Domain of TGF-β-Receptor-3 (TGFR-3)

Effectiveness of BMP-2 and PDGF-BB Adsorption onto a Collagen/Collagen-Magnesium-Hydroxyapatite Scaffold in Weight-Bearing and Non-Weight-Bearing Osteochondral Defect Bone Repair: In Vitro, Ex Vivo and In Vivo Evaluation

A GDF5 point mutation strikes twice--causing BDA1 and SYNS2

Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN

Molecular recognition in bone morphogenetic protein (BMP)/receptor interaction

Structure Analysis of Bone Morphogenetic Protein-2 Type I Receptor Complexes Reveals a Mechanism of Receptor Inactivation in Juvenile Polyposis Syndrome

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