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Promiscuity and specificity in BMP receptor activation

FEBS letters, 2012-07, Vol.586 (14), p.1846-1859

2012

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Specification of BMP Signaling

Cells (Basel, Switzerland), 2019-12, Vol.8 (12), p.1579

2019

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Unraveling the Connection between Fibroblast Growth Factor and Bone Morphogenetic Protein Signaling

International journal of molecular sciences, 2018-10, Vol.19 (10), p.3220

2018

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Release and bioactivity of bone morphogenetic protein-2 are affected by scaffold binding techniques in vitro and in vivo

Journal of controlled release, 2015-01, Vol.197, p.148-157

2015

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Enhanced reconstruction of long bone architecture by a growth factor mutant combining positive features of GDF-5 and BMP-2

Biomaterials, 2013-08, Vol.34 (24), p.5926-5936

2013

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Receptor oligomerization and beyond: a case study in bone morphogenetic proteins

BMC biology, 2009-09, Vol.7 (1), p.59-59, Article 59

2009

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Site-Directed Immobilization of an Engineered Bone Morphogenetic Protein 2 (BMP2) Variant to Collagen-Based Microspheres Induces Bone Formation In Vivo

International journal of molecular sciences, 2022-04, Vol.23 (7), p.3928

2022

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Growth on Metallo-Supramolecular Coordination Polyelectrolyte (MEPE) Stimulates Osteogenic Differentiation of Human Osteosarcoma Cells (MG63) and Human Bone Marrow Derived Mesenchymal Stem Cells

Polymers, 2019-06, Vol.11 (7), p.1090

2019

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Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity

The EMBO journal, 2009-04, Vol.28 (7), p.937-947

2009

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GDF-5 can act as a context-dependent BMP-2 antagonist

BMC biology, 2015-09, Vol.13 (1), p.77-77, Article 77

2015

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The anti-myeloma activity of bone morphogenetic protein 2 predominantly relies on the induction of growth arrest and is apoptosis-independent

PloS one, 2017-10, Vol.12 (10), p.e0185720-e0185720

2017

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Comparative in vitro treatment of mesenchymal stromal cells with GDF-5 and R57A induces chondrogenic differentiation while limiting chondrogenic hypertrophy

Journal of experimental orthopaedics, 2023-03, Vol.10 (1), p.29-n/a

2023

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Anisotropic Cryostructured Collagen Scaffolds for Efficient Delivery of RhBMP–2 and Enhanced Bone Regeneration

Materials, 2019-09, Vol.12 (19), p.3105

2019

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Utilizing BMP-2 muteins for treatment of multiple myeloma

PloS one, 2017-05, Vol.12 (5), p.e0174884-e0174884

2017

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von Willebrand Factor Type C Domain-containing Proteins Regulate Bone Morphogenetic Protein Signaling through Different Recognition Mechanisms

The Journal of biological chemistry, 2007-07, Vol.282 (27), p.20002-20014

2007

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Addition of heparin binding sites strongly increases the bone forming capabilities of BMP9 in vivo

Bioactive materials, 2023-11, Vol.29, p.241-250

2023

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Functional Antibodies Targeting IsaA of Staphylococcus aureus Augment Host Immune Response and Open New Perspectives for Antibacterial Therapy

Antimicrobial Agents and Chemotherapy, 2011-01, Vol.55 (1), p.165-173

2011

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Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand

The FEBS journal, 2008-01, Vol.275 (1), p.172-183

2008

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Molecular recognition of BMP-2 and BMP receptor IA

Nature structural & molecular biology, 2004-05, Vol.11 (5), p.481-488

2004

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Identification of a Novel TGF-β-Binding Site in the Zona Pellucida C-terminal (ZP-C) Domain of TGF-β-Receptor-3 (TGFR-3)

PloS one, 2013-06, Vol.8 (6), p.e67214-e67214

2013

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Effectiveness of BMP-2 and PDGF-BB Adsorption onto a Collagen/Collagen-Magnesium-Hydroxyapatite Scaffold in Weight-Bearing and Non-Weight-Bearing Osteochondral Defect Bone Repair: In Vitro, Ex Vivo and In Vivo Evaluation

Journal of functional biomaterials, 2023-02, Vol.14 (2), p.111

2023

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A GDF5 point mutation strikes twice--causing BDA1 and SYNS2

PLoS genetics, 2013-10, Vol.9 (10), p.e1003846-e1003846

2013

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Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN

PLoS genetics, 2009-11, Vol.5 (11), p.e1000747-e1000747

2009

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Molecular recognition in bone morphogenetic protein (BMP)/receptor interaction

Biological chemistry, 2004-08, Vol.385 (8), p.697-710

2004

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Structure Analysis of Bone Morphogenetic Protein-2 Type I Receptor Complexes Reveals a Mechanism of Receptor Inactivation in Juvenile Polyposis Syndrome

The Journal of biological chemistry, 2008-02, Vol.283 (9), p.5876-5887

2008

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Promiscuity and specificity in BMP receptor activation

Specification of BMP Signaling

Unraveling the Connection between Fibroblast Growth Factor and Bone Morphogenetic Protein Signaling

Release and bioactivity of bone morphogenetic protein-2 are affected by scaffold binding techniques in vitro and in vivo

Enhanced reconstruction of long bone architecture by a growth factor mutant combining positive features of GDF-5 and BMP-2

Receptor oligomerization and beyond: a case study in bone morphogenetic proteins

Site-Directed Immobilization of an Engineered Bone Morphogenetic Protein 2 (BMP2) Variant to Collagen-Based Microspheres Induces Bone Formation In Vivo

Growth on Metallo-Supramolecular Coordination Polyelectrolyte (MEPE) Stimulates Osteogenic Differentiation of Human Osteosarcoma Cells (MG63) and Human Bone Marrow Derived Mesenchymal Stem Cells

Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity

GDF-5 can act as a context-dependent BMP-2 antagonist

The anti-myeloma activity of bone morphogenetic protein 2 predominantly relies on the induction of growth arrest and is apoptosis-independent

Comparative in vitro treatment of mesenchymal stromal cells with GDF-5 and R57A induces chondrogenic differentiation while limiting chondrogenic hypertrophy

Anisotropic Cryostructured Collagen Scaffolds for Efficient Delivery of RhBMP–2 and Enhanced Bone Regeneration

Utilizing BMP-2 muteins for treatment of multiple myeloma

von Willebrand Factor Type C Domain-containing Proteins Regulate Bone Morphogenetic Protein Signaling through Different Recognition Mechanisms

Addition of heparin binding sites strongly increases the bone forming capabilities of BMP9 in vivo

Functional Antibodies Targeting IsaA of Staphylococcus aureus Augment Host Immune Response and Open New Perspectives for Antibacterial Therapy

Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand

Molecular recognition of BMP-2 and BMP receptor IA

Identification of a Novel TGF-β-Binding Site in the Zona Pellucida C-terminal (ZP-C) Domain of TGF-β-Receptor-3 (TGFR-3)

Effectiveness of BMP-2 and PDGF-BB Adsorption onto a Collagen/Collagen-Magnesium-Hydroxyapatite Scaffold in Weight-Bearing and Non-Weight-Bearing Osteochondral Defect Bone Repair: In Vitro, Ex Vivo and In Vivo Evaluation

A GDF5 point mutation strikes twice--causing BDA1 and SYNS2

Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN

Molecular recognition in bone morphogenetic protein (BMP)/receptor interaction

Structure Analysis of Bone Morphogenetic Protein-2 Type I Receptor Complexes Reveals a Mechanism of Receptor Inactivation in Juvenile Polyposis Syndrome

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